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Volumetric imaging by fluorescence microscopy is often limited by anisotropic spatial resolution from inferior axial resolution compared to the lateral resolution. To address this problem, here we present a deep-learning-enabled…
Alzheimer's disease is a progressive neurodegenerative disorder that gradually deprives the patient of cognitive function and can end in death. With the advancement of technology today, it is possible to detect Alzheimer's disease through…
In recent years, deep learning has become a breakthrough technique in assisting medical image diagnosis. Supervised learning using convolutional neural networks (CNN) provides state-of-the-art performance and has served as a benchmark for…
Learning similarity is a key aspect in medical image analysis, particularly in recommendation systems or in uncovering the interpretation of anatomical data in images. Most existing methods learn such similarities in the embedding space…
Amyotrophic Lateral Sclerosis (ALS) and Myopathy are debilitating neuromuscular disorders that demand accurate and efficient diagnostic approaches. In this study, we harness the power of deep learning techniques to detect ALS and Myopathy.…
Traditional deep learning models rely on methods such as softmax cross-entropy and ArcFace loss for tasks like classification and face recognition. These methods mainly explore angular features in a hyperspherical space, often resulting in…
Alzheimers Disease (AD) is a progressive neurodegenerative disorder that poses significant challenges in its early diagnosis, often leading to delayed treatment and poorer outcomes for patients. Traditional diagnostic methods, typically…
Colloidoscope is a deep learning pipeline employing a 3D residual Unet architecture, designed to enhance the tracking of dense colloidal suspensions through confocal microscopy. This methodology uses a simulated training dataset that…
Early and accurate diagnosis of Alzheimer's disease (AD) and its prodromal period mild cognitive impairment (MCI) is essential for the delayed disease progression and the improved quality of patients'life. The emerging computer-aided…
Background: An early diagnosis together with an accurate disease progression monitoring of multiple sclerosis is an important component of successful disease management. Prior studies have established that multiple sclerosis is correlated…
Ventricular volume and its progression are known to be linked to several brain diseases such as dementia and schizophrenia. Therefore accurate measurement of ventricle volume is vital for longitudinal studies on these disorders, making…
Deep learning methods based on Convolutional Neural Networks (CNNs) have shown great potential to improve early and accurate diagnosis of Alzheimer's disease (AD) dementia based on imaging data. However, these methods have yet to be widely…
Automatic pulmonary nodules classification is significant for early diagnosis of lung cancers. Recently, deep learning techniques have enabled remarkable progress in this field. However, these deep models are typically of high computational…
Statistical analysis of magnetic resonance imaging (MRI) can help radiologists to detect pathologies that are otherwise likely to be missed. Deep learning (DL) has shown promise in modeling complex spatial data for brain anomaly detection.…
With the development of deep learning, medical image classification has been significantly improved. However, deep learning requires massive data with labels. While labeling the samples by human experts is expensive and time-consuming,…
Amyotrophic lateral sclerosis (ALS) is incurable neurological disorder with rapidly progressive course. Common early symptoms of ALS are difficulty in swallowing and speech. However, early acoustic manifestation of speech and voice symptoms…
Deep learning techniques are increasingly being adopted in diagnostic medical imaging. However, the limited availability of high-quality, large-scale medical datasets presents a significant challenge, often necessitating the use of transfer…
Alzheimer's disease (AD) is a neurodegenerative disorder affecting millions worldwide, necessitating early and accurate diagnosis for optimal patient management. In recent years, advancements in deep learning have shown remarkable potential…
Histopathological characterization of colorectal polyps is an important principle for determining the risk of colorectal cancer and future rates of surveillance for patients. This characterization is time-intensive, requires years of…
This paper demonstrates a self-supervised framework for learning voxel-wise coarse-to-fine representations tailored for dense downstream tasks. Our approach stems from the observation that existing methods for hierarchical representation…