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Enlarged perivascular spaces (PVS) are increasingly recognized as biomarkers of cerebral small vessel disease, Alzheimer's disease, stroke, and aging-related neurodegeneration. However, manual segmentation of PVS is time-consuming and…

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease of the brain and the spinal cord, which leads to paralysis of motor functions. Patients retain their ability to blink, which can be used for communication. Here,…

Computer Vision and Pattern Recognition · Computer Science 2021-07-01 Albara Ah Ramli , Rex Liu , Rahul Krishnamoorthy , Vishal I B , Xiaoxiao Wang , Ilias Tagkopoulos , Xin Liu

Image segmentation is one of the most essential biomedical image processing problems for different imaging modalities, including microscopy and X-ray in the Internet-of-Medical-Things (IoMT) domain. However, annotating biomedical images is…

Computer Vision and Pattern Recognition · Computer Science 2021-01-25 Ziyuan Zhao , Zeng Zeng , Kaixin Xu , Cen Chen , Cuntai Guan

The hydrocephalus can be either an independent disease or a concomitant symptom of a number of pathologies, therefore representing an urgent issue in the present-day clinical practice. Deep Learning is an evolving technology and the part of…

Computer Vision and Pattern Recognition · Computer Science 2019-09-27 Alexey Demyanchuk , Ekaterina Pushkina , Nikolay Russkikh , Dmitry Shtokalo , Sergey Mishinov

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition whose rising prevalence places increasing demands on a lengthy diagnostic process. Machine learning (ML) has shown promise in automating ASD diagnosis, but most…

Artificial Intelligence · Computer Science 2025-12-09 Gondy Leroy , Prakash Bisht , Sai Madhuri Kandula , Nell Maltman , Sydney Rice

Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized by a rapid motor decline, leading to respiratory failure and subsequently to death. In this context, researchers have sought for models to automatically…

Machine Learning · Computer Science 2019-07-31 Telma Pereira , Sofia Pires , Marta Gromicho , Susana Pinto , Mamede de Carvalho , Sara C. Madeira

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

Convolutional Neural Network (CNN) has been successfully applied on classification of both natural images and medical images but not yet been applied to differentiating patients with schizophrenia from healthy controls. Given the subtle,…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Mengjiao Hu , Kang Sim , Juan Helen Zhou , Xudong Jiang , Cuntai Guan

Colon polyps are precursors to colorectal cancer, a leading cause of cancer-related mortality worldwide. Early detection is critical for improving patient outcomes. This study investigates the application of deep learning-based object…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Md Al Amin , Bikash Kumar Paul

We present a method combining affinity prediction with region agglomeration, which improves significantly upon the state of the art of neuron segmentation from electron microscopy (EM) in accuracy and scalability. Our method consists of a…

Computer Vision and Pattern Recognition · Computer Science 2020-07-29 Jan Funke , Fabian David Tschopp , William Grisaitis , Arlo Sheridan , Chandan Singh , Stephan Saalfeld , Srinivas C. Turaga

Purpose: Hard-to-interpret Black-box Machine Learning (ML) were often used for early Alzheimer's Disease (AD) detection. Methods: To interpret eXtreme Gradient Boosting (XGBoost), Random Forest (RF), and Support Vector Machine (SVM)…

Machine Learning · Computer Science 2022-11-08 Louise Bloch , Christoph M. Friedrich

The ability to dynamically extend a model to new data and classes is critical for multiple organ and tumor segmentation. However, due to privacy regulations, accessing previous data and annotations can be problematic in the medical domain.…

Image and Video Processing · Electrical Eng. & Systems 2023-07-24 Yixiao Zhang , Xinyi Li , Huimiao Chen , Alan Yuille , Yaoyao Liu , Zongwei Zhou

Early diagnosis is essential for the successful treatment of bowel cancers including colorectal cancer (CRC) and capsule endoscopic imaging with robotic actuation can be a valuable diagnostic tool when combined with automated image…

Magnetic Resonance Imaging (MRI) plays a pivotal role in the early diagnosis and monitoring of Alzheimer's disease (AD). However, the subtle structural variations in brain MRI scans often pose challenges for conventional deep learning…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Faisal Ahmed

Alzheimer's Disease (AD) is a neurodegenerative disease that is one of the significant causes of death in the elderly population. Many deep learning techniques have been proposed to diagnose AD using Magnetic Resonance Imaging (MRI) scans.…

Image and Video Processing · Electrical Eng. & Systems 2022-07-05 A. H. Rashid , A. Gupta , J. Gupta , M. Tanveer

Medical images, especially volumetric images, are of high resolution and often exceed the capacity of standard desktop GPUs. As a result, most deep learning-based medical image analysis tasks require the input images to be downsampled,…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Jianning Li , Antonio Pepe , Christina Gsaxner , Yuan Jin , Jan Egger

In this letter, we introduce deep active learning (AL) for multi-label classification (MLC) problems in remote sensing (RS). In particular, we investigate the effectiveness of several AL query functions for MLC of RS images. Unlike the…

Computer Vision and Pattern Recognition · Computer Science 2023-09-26 Lars Möllenbrok , Gencer Sumbul , Begüm Demir

Identification of vessel structures of different sizes in biomedical images is crucial in the diagnosis of many neurodegenerative diseases. However, the sparsity of good-quality annotations of such images makes the task of vessel…

Deep neural networks have led to state-of-the-art results in many medical imaging tasks including Alzheimer's disease (AD) detection based on structural magnetic resonance imaging (MRI) data. However, the network decisions are often…

Quantitative Methods · Quantitative Biology 2019-08-28 Moritz Böhle , Fabian Eitel , Martin Weygandt , Kerstin Ritter

Segmenting a structural magnetic resonance imaging (MRI) scan is an important pre-processing step for analytic procedures and subsequent inferences about longitudinal tissue changes. Manual segmentation defines the current gold standard in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Alex Fedorov , Jeremy Johnson , Eswar Damaraju , Alexei Ozerin , Vince Calhoun , Sergey Plis
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