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Interacting systems are prevalent in nature, from dynamical systems in physics to complex societal dynamics. The interplay of components can give rise to complex behavior, which can often be explained using a simple model of the system's…
While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…
Unsupervised learning with functional data is an emerging paradigm of machine learning research with applications to computer vision, climate modeling and physical systems. A natural way of modeling functional data is by learning operators…
We introduce a new method for learning Bayesian neural networks, treating them as a stack of multivariate Bayesian linear regression models. The main idea is to infer the layerwise posterior exactly if we know the target outputs of each…
We present Submatrix-wise Vector Embedding Learner (Swivel), a method for generating low-dimensional feature embeddings from a feature co-occurrence matrix. Swivel performs approximate factorization of the point-wise mutual information…
A novel and efficient end-to-end learning model for automatic modulation classification is proposed for wireless spectrum monitoring applications, which automatically learns from the time domain in-phase and quadrature data without…
Network inference, the task of reconstructing interactions in a complex system from experimental observables, is a central yet extremely challenging problem in systems biology. While much progress has been made in the last two decades,…
Background: Single-cell RNA sequencing (scRNA-seq) yields valuable insights about gene expression and gives critical information about complex tissue cellular composition. In the analysis of single-cell RNA sequencing, the annotations of…
Recent advances in neural variational inference have spawned a renaissance in deep latent variable models. In this paper we introduce a generic variational inference framework for generative and conditional models of text. While traditional…
Causal disentanglement has great potential for capturing complex situations. However, there is a lack of practical and efficient approaches. It is already known that most unsupervised disentangling methods are unable to produce identifiable…
Existing subset selection methods for efficient learning predominantly employ discrete combinatorial and model-specific approaches which lack generalizability. For an unseen architecture, one cannot use the subset chosen for a different…
Single neuron models have a long tradition in computational neuroscience. Detailed biophysical models such as the Hodgkin-Huxley model as well as simplified neuron models such as the class of integrate-and-fire models relate the input…
Graphical models can represent a multivariate distribution in a convenient and accessible form as a graph. Causal models can be viewed as a special class of graphical models that not only represent the distribution of the observed system…
We present a method for feature interpretation that makes use of recent advances in autoregressive density estimation models to invert model representations. We train generative inversion models to express a distribution over input features…
Deep learning methods achieve great success recently on many computer vision problems, with image classification and object detection as the prominent examples. In spite of these practical successes, optimization of deep networks remains an…
Single-cell gene expression measurements encode variability spanning molecular noise, cell-to-cell heterogeneity, and technical artifacts. Mechanistic stochastic models provide powerful approaches to disentangle these sources, yet inferring…
We propose a framework for the statistical evaluation of variational auto-encoders (VAEs) and test two instances of this framework in the context of modelling images of handwritten digits and a corpus of English text. Our take on evaluation…
Background: Several sources of noise obfuscate the identification of single nucleotide variation (SNV) in next generation sequencing data. For instance, errors may be introduced during library construction and sequencing steps. In addition,…
Neural simulation-based inference (SBI) is a popular set of methods for Bayesian inference when models are only available in the form of a simulator. These methods are widely used in the sciences and engineering, where writing down a…
We study the dynamics of stochastic gradient descent (SGD) for a class of sequence models termed Sequence Single-Index (SSI) models, where the target depends on a single direction in input space applied to a sequence of tokens. This setting…