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Interacting systems are prevalent in nature, from dynamical systems in physics to complex societal dynamics. The interplay of components can give rise to complex behavior, which can often be explained using a simple model of the system's…

Machine Learning · Statistics 2018-06-07 Thomas Kipf , Ethan Fetaya , Kuan-Chieh Wang , Max Welling , Richard Zemel

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

Machine Learning · Computer Science 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

Unsupervised learning with functional data is an emerging paradigm of machine learning research with applications to computer vision, climate modeling and physical systems. A natural way of modeling functional data is by learning operators…

Machine Learning · Computer Science 2023-02-22 Jacob H. Seidman , Georgios Kissas , George J. Pappas , Paris Perdikaris

We introduce a new method for learning Bayesian neural networks, treating them as a stack of multivariate Bayesian linear regression models. The main idea is to infer the layerwise posterior exactly if we know the target outputs of each…

Machine Learning · Computer Science 2024-11-20 Richard Kurle , Alexej Klushyn , Ralf Herbrich

We present Submatrix-wise Vector Embedding Learner (Swivel), a method for generating low-dimensional feature embeddings from a feature co-occurrence matrix. Swivel performs approximate factorization of the point-wise mutual information…

Computation and Language · Computer Science 2016-02-09 Noam Shazeer , Ryan Doherty , Colin Evans , Chris Waterson

A novel and efficient end-to-end learning model for automatic modulation classification is proposed for wireless spectrum monitoring applications, which automatically learns from the time domain in-phase and quadrature data without…

Signal Processing · Electrical Eng. & Systems 2021-01-21 Kaisheng Liao , Yaodong Zhao , Jie Gu , Yaping Zhang , Yi Zhong

Network inference, the task of reconstructing interactions in a complex system from experimental observables, is a central yet extremely challenging problem in systems biology. While much progress has been made in the last two decades,…

Quantitative Methods · Quantitative Biology 2024-09-12 Stephen Y Zhang

Background: Single-cell RNA sequencing (scRNA-seq) yields valuable insights about gene expression and gives critical information about complex tissue cellular composition. In the analysis of single-cell RNA sequencing, the annotations of…

Genomics · Quantitative Biology 2023-03-29 Xiaowen Cao , Li Xing , Elham Majd , Hua He , Junhua Gu , Xuekui Zhang

Recent advances in neural variational inference have spawned a renaissance in deep latent variable models. In this paper we introduce a generic variational inference framework for generative and conditional models of text. While traditional…

Computation and Language · Computer Science 2016-06-07 Yishu Miao , Lei Yu , Phil Blunsom

Causal disentanglement has great potential for capturing complex situations. However, there is a lack of practical and efficient approaches. It is already known that most unsupervised disentangling methods are unable to produce identifiable…

Machine Learning · Computer Science 2023-11-14 Heejeong Nam

Existing subset selection methods for efficient learning predominantly employ discrete combinatorial and model-specific approaches which lack generalizability. For an unseen architecture, one cannot use the subset chosen for a different…

Machine Learning · Computer Science 2024-09-20 Eeshaan Jain , Tushar Nandy , Gaurav Aggarwal , Ashish Tendulkar , Rishabh Iyer , Abir De

Single neuron models have a long tradition in computational neuroscience. Detailed biophysical models such as the Hodgkin-Huxley model as well as simplified neuron models such as the class of integrate-and-fire models relate the input…

Neurons and Cognition · Quantitative Biology 2016-11-02 Simone Carlo Surace , Jean-Pascal Pfister

Graphical models can represent a multivariate distribution in a convenient and accessible form as a graph. Causal models can be viewed as a special class of graphical models that not only represent the distribution of the observed system…

Methodology · Statistics 2017-06-29 Christina Heinze-Deml , Marloes H. Maathuis , Nicolai Meinshausen

We present a method for feature interpretation that makes use of recent advances in autoregressive density estimation models to invert model representations. We train generative inversion models to express a distribution over input features…

Machine Learning · Statistics 2019-01-03 Charlie Nash , Nate Kushman , Christopher K. I. Williams

Deep learning methods achieve great success recently on many computer vision problems, with image classification and object detection as the prominent examples. In spite of these practical successes, optimization of deep networks remains an…

Computer Vision and Pattern Recognition · Computer Science 2017-03-21 Kui Jia

Single-cell gene expression measurements encode variability spanning molecular noise, cell-to-cell heterogeneity, and technical artifacts. Mechanistic stochastic models provide powerful approaches to disentangle these sources, yet inferring…

Quantitative Methods · Quantitative Biology 2025-09-19 Christopher E. Miles

We propose a framework for the statistical evaluation of variational auto-encoders (VAEs) and test two instances of this framework in the context of modelling images of handwritten digits and a corpus of English text. Our take on evaluation…

Machine Learning · Computer Science 2022-04-08 Claartje Barkhof , Wilker Aziz

Background: Several sources of noise obfuscate the identification of single nucleotide variation (SNV) in next generation sequencing data. For instance, errors may be introduced during library construction and sequencing steps. In addition,…

Genomics · Quantitative Biology 2015-03-05 Steve Hoffmann , Peter F. Stadler , Korbinian Strimmer

Neural simulation-based inference (SBI) is a popular set of methods for Bayesian inference when models are only available in the form of a simulator. These methods are widely used in the sciences and engineering, where writing down a…

Machine Learning · Statistics 2026-01-15 Yuga Hikida , Ayush Bharti , Niall Jeffrey , François-Xavier Briol

We study the dynamics of stochastic gradient descent (SGD) for a class of sequence models termed Sequence Single-Index (SSI) models, where the target depends on a single direction in input space applied to a sequence of tokens. This setting…

Machine Learning · Statistics 2025-11-13 Luca Arnaboldi , Bruno Loureiro , Ludovic Stephan , Florent Krzakala , Lenka Zdeborova
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