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In this work and the supporting Parts II [2] and III [3], we provide a rather detailed analysis of the stability and performance of asynchronous strategies for solving distributed optimization and adaptation problems over networks. We…

Systems and Control · Computer Science 2014-12-17 Xiaochuan Zhao , Ali H. Sayed

In this paper, we provide a detailed theoretical analysis of the numerical scheme introduced in J. Comput. Phys. 436 (2021) 110253 for the reaction kinetics of a class of chemical reaction networks that satisfies detailed balance condition.…

Numerical Analysis · Mathematics 2024-02-07 Chun Liu , Cheng Wang , Yiwei Wang

We consider stochastically modeled chemical reaction systems with mass-action kinetics and prove that a product-form stationary distribution exists for each closed, irreducible subset of the state space if an analogous deterministically…

Probability · Mathematics 2010-01-31 David F. Anderson , Gheorghe Craciun , Thomas G. Kurtz

We show that discrete distributions on the $d$-dimensional non-negative integer lattice can be approximated arbitrarily well via the marginals of stationary distributions for various classes of stochastic chemical reaction networks. We…

Computational Complexity · Computer Science 2019-10-01 Daniele Cappelletti , Andrés Ortiz-Muñoz , David Anderson , Erik Winfree

The concept of limiting step gives the limit simplification: the whole network behaves as a single step. However, in its simplest form this idea is applicable only to the simplest linear cycles in steady states. For such the simplest cycles…

Chemical Physics · Physics 2008-06-23 A. N. Gorban , O. Radulescu

We prove that a system of $N$ fermions interacting with an additional particle via point interactions is stable if the ratio of the mass of the additional particle to the one of the fermions is larger than some critical $m^*$. The value of…

Mathematical Physics · Physics 2017-11-23 Thomas Moser , Robert Seiringer

We determine the $N$-particle stationary states of a staggered stochastic hopping model with reflective boundaries. It is shown that the stationary states are in fact so-called optimum ground states. Recursion relations in the particle…

Statistical Mechanics · Physics 2007-05-23 Kai Klauck , Andreas Schadschneider , Johannes Zittartz

We present a systematic procedure for testing whether reaction networks exhibit non-expansivity or monotonicity. This procedure identifies explicit norms under which a network is non-expansive or cones for which the system is monotone-or…

Dynamical Systems · Mathematics 2025-01-28 Alon Duvall

The stable operation of the electric power grid relies on a precisely synchronized state of all generators and machines. All machines rotate at exactly the same frequency with fixed phase differences, leading to steady power flows…

Adaptation and Self-Organizing Systems · Physics 2020-01-09 Chiara Balestra , Franz Kaiser , Debsankha Manik , Dirk Witthaut

Stochastic reaction networks, which are usually modeled as continuous-time Markov chains on $\mathbb Z^d_{\ge 0}$, and simulated via a version of the "Gillespie algorithm," have proven to be a useful tool for the understanding of processes,…

Probability · Mathematics 2025-07-15 David F. Anderson , Aidan S. Howells

We provide a Jacobian criterion that applies to arbitrary chemical reaction networks taken with mass-action kinetics to preclude the existence of multiple positive steady states within any stoichiometric class for any choice of rate…

Algebraic Geometry · Mathematics 2011-12-21 Elisenda Feliu , Carsten Wiuf

For infinitely large sparse networks of spiking neurons mean field theory shows that a balanced state of highly irregular activity arises under various conditions. Here we analytically investigate the microscopic irregular dynamics in…

Disordered Systems and Neural Networks · Physics 2009-11-13 Sven Jahnke , Raoul-Martin Memmesheimer , Marc Timme

We present a computational procedure to characterize the signs of sensitivities of steady states to parameter perturbations in chemical reaction networks.

Quantitative Methods · Quantitative Biology 2013-12-31 Eduardo D. Sontag

Reaction networks (RNs) comprise a set $X$ of species and a set $\mathscr{R}$ of reactions $Y\to Y'$, each converting a multiset of educts $Y\subseteq X$ into a multiset $Y'\subseteq X$ of products. RNs are equivalent to directed…

Molecular Networks · Quantitative Biology 2022-01-06 Stefan Müller , Christoph Flamm , Peter F. Stadler

Zero-one biochemical reaction networks are widely recognized for their importance in analyzing signal transduction and cellular decision-making processes. Degenerate networks reveal non-standard behaviors and mark the boundary where…

Molecular Networks · Quantitative Biology 2025-12-01 Xiaoxian Tang , Yihan Wang , Jiandong Zhang

We study the uniqueness of steady states of strong-KPP reaction--diffusion equations in general domains under various boundary conditions. We show that positive bounded steady states are unique provided the domain satisfies a certain…

Analysis of PDEs · Mathematics 2022-12-14 Henri Berestycki , Cole Graham

We study the response of chemical reaction networks driven far from equilibrium to logarithmic perturbations of reaction rates. The response of the mean number of a chemical species is observed to be quantitively limited by number…

Statistical Mechanics · Physics 2023-05-09 Hyun-Myung Chun , Jordan M. Horowitz

Robustness to mutations and noise has been shown to evolve through stabilizing selection for optimal phenotypes in model gene regulatory networks. The ability to evolve robust mutants is known to depend on the network architecture. How do…

Molecular Networks · Quantitative Biology 2008-07-07 Volkan Sevim , Per Arne Rikvold

According to the chemical reaction network theory, the topology of a certain class of chemical reaction networks, regardless of the kinetic details, sets a limit on the dynamical properties that a particular network can potentially admit;…

Molecular Networks · Quantitative Biology 2014-08-21 Jaewook Joo , Sanjeev Chauhan

We study the set of output stable configurations of chemical reaction deciders (CRDs). It turns out that CRDs with only bimolecular reactions (which are almost equivalent to population protocols) have a special structure that allows for an…

Computational Complexity · Computer Science 2015-06-16 Robert Brijder
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