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Related papers: Simulation of Intravoxel Incoherent Perfusion Sign…

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Variability of IVIM parameters throughout the literature is a long-standing issue, and perfusion-related parameters are difficult to interpret. We demonstrate for improving the analysis of intravoxel incoherent motion imaging (IVIM)…

Medical Physics · Physics 2024-01-05 Caleb Sample , Jonn Wu , Haley Clark

We develop a general analytical and numerical framework for estimating intra- and extra-neurite water fractions and diffusion coefficients, as well as neurite orientational dispersion, in each imaging voxel. By employing a set of rotational…

Biological Physics · Physics 2018-04-10 Dmitry S. Novikov , Jelle Veraart , Ileana O. Jelescu , Els Fieremans

High-resolution blood flow simulations have potential for developing better understanding biophysical phenomena at the microscale, such as vasodilation, vasoconstriction and overall vascular resistance. To this end, we present a scalable…

Computational Engineering, Finance, and Science · Computer Science 2019-09-26 Libin Lu , Matthew J. Morse , Abtin Rahimian , Georg Stadler , Denis Zorin

Large neck vessels (carotid artery and internal jugular vein, IJV) offer a unique opportunity to monitor hemodynamics non-invasively by optical means. The primary shortcoming of past work has been the focus on healthy volunteers in normal…

Currently, free flaps and pedicled flaps are assessed for reperfusion in post-operative care using colour, capillary refill, temperature, texture and Doppler signal (if available). While these techniques are effective, they are prone to…

Medical Physics · Physics 2022-04-18 Mark Main , Richard JJ Pilkington , Graham M Gibson , Akhil Kallepalli

We used volume-of-fluid (VOF) method to perform three-dimensional numerical simulations of droplet formation of Newtonian fluids in microfluidic T-junction devices. To evaluate the performance of the VOF method we examined the regimes of…

Fluid Dynamics · Physics 2017-04-26 Mehdi Nekouei , Siva A. Vanapalli

The stability of most surface-tension-driven interfacial flow simulations is governed by the capillary time-step constraint. This concerns particularly small-scale flows and, more generally, highly-resolved liquid-gas simulations with…

Fluid Dynamics · Physics 2024-10-24 Romain Janodet , Berend van Wachem , Fabian Denner

Scientists have long sought to understand how vascular networks supply blood and oxygen to cells throughout the body. Recent work focuses on principles that constrain how vessel size changes through branching generations from the aorta to…

Tissues and Organs · Quantitative Biology 2015-09-10 Mitchell G Newberry , Daniel B Ennis , Van M Savage

We study compressible fluid flow in narrow two-dimensional channels using a novel molecular dynamics simulation method. In the simulation area, an upstream source is maintained at constant density and temperature while a downstream…

Condensed Matter · Physics 2009-10-22 M. Sun , C. Ebner

The flow of cerebrospinal fluid through the perivascular spaces of the brain is believed to play a crucial role in eliminating toxic waste proteins. While the driving forces of this flow have been enigmatic, experiments have shown that…

Analysis of PDEs · Mathematics 2024-01-02 Ingeborg G. Gjerde , Miroslav Kuchta , Marie E. Rognes , Barbara Wohlmuth

Infrared light scattering methods have been developed and employed to non-invasively monitor human cerebral blood flow (CBF). However, the number of reflected photons that interact with the brain is low when detecting blood flow in deep…

Medical Physics · Physics 2020-09-02 J. Xu , A. K. Jahromi , J. Brake , J. E. Robinson , C. Yang

Estimation of blood oxygenation with spectroscopic photoacoustic imaging is a promising tool for several biomedical applications. For this method to be quantitative, it relies on an accurate method of the light fluence in the tissue. This…

Image and Video Processing · Electrical Eng. & Systems 2019-11-06 Geoffrey P. Luke , Kevin Hoffer-Hawlik , Austin C. Van Namen , Ruibo Shang

In this paper, a novel deep learning framework is proposed for temporal super-resolution simulation of blood vessel flows, in which a high-temporal-resolution time-varying blood vessel flow simulation is generated from a…

Image and Video Processing · Electrical Eng. & Systems 2021-11-23 Zhizheng Jiang , Fei Gao , Renshu Gu , Jinlan Xu , Gang Xu , Timon Rabczuk

We present a photoacoustic computed tomography investigation on a healthy human finger, to image blood vessels with a focus on vascularity across the interphalangeal joints. The cross-sectional images were acquired using an imager…

Methods of Computational Fluid Dynamics are applied to simulate pulsatile blood flow in human vessels and in the aortic arch. The non-Newtonian behaviour of the human blood is investigated in simple vessels of actual size. A detailed…

Computational Physics · Physics 2008-02-19 Renat A. Sultanov , Dennis Guster , Brent Engelbrekt , Richard Blankenbecler

The present research proposes a new memory-efficient method using diffusion models to inject turbulent inflow conditions into Large Eddy Simulation (LES) and Direct Numerical Simulation (DNS) for various flow problems. A guided diffusion…

Understanding the physics of blood is challenging due to its nature as a suspension of soft particles and the fact that typical problems involve different scales. This is valid also for numerical investigations. In fact, many computational…

Soft Condensed Matter · Physics 2011-09-16 Florian Janoschek , Federico Toschi , Jens Harting

Color Doppler by transthoracic echocardiography creates 2-D fan-shaped maps of blood velocities in the cardiac cavities. It is a one-component velocimetric technique since it only returns the velocity components parallel to the ultrasound…

A numerical model is developed for the motion of superparamagnetic nanoparticles in a non-Newtonian blood flow under the influence of a magnetic field. The rheological properties of blood are modeled by the Carreau flow and viscosity, and…

Biological Physics · Physics 2022-07-14 M. Lee , A. Shelke , S. Singh , J. Fan , P. Zaleski , S. Afkhami

Intravascular ultrasound (IVUS) imaging allows direct visualization of the coronary vessel wall and is suitable for the assessment of atherosclerosis and the degree of stenosis. Accurate segmentation and measurements of lumen and…

Computer Vision and Pattern Recognition · Computer Science 2021-02-23 Fubao Zhu , Zhengyuan Gao , Chen Zhao , Hanlei Zhu , Yong Dong , Jingfeng Jiang , Neng Dai , Weihua Zhou