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Natural structural materials, such as bone and wood, can autonomously adapt their mechanical properties in response to loading to prevent failure. They smartly control the addition of material in locations of high stress by utilizing…

Many genetic mutations adversely affect the structure and function of load-bearing soft tissues, with clinical sequelae often responsible for disability or death. Parallel advances in genetics and histomechanical characterization provide…

Tissues and Organs · Quantitative Biology 2023-01-11 Enrui Zhang , Bart Spronck , Jay D. Humphrey , George Em Karniadakis

Biological systems evolve with minimum metabolic costs and use common components, and they represent guideposts toward a paradigm of manufacturing that is centered on minimum energy, local resources, and ecological integration. Here, a new…

Soft Condensed Matter · Physics 2024-07-26 Shiwei Ng , Benjamin Ng Guan Zhi , Robert E. Simpson , Javier G. Fernandez

We study the frequency dependence of the effective electromagnetic parameters of left-handed and related meta-materials of the split ring resonator and wire type. We show that the reduced translational symmetry (periodic structure) inherent…

Materials Science · Physics 2009-11-10 Th. Koschny , P. Markos , E. N. Economou , D. R. Smith , D. C. Vier , C. M. Soukoulis

Mechanical metamaterials are engineered materials that gain their remarkable mechanical properties, such as negative Poisson's ratios, negative compressibility, phononic bandgaps, and topological phonon modes, from their structure rather…

Soft Condensed Matter · Physics 2017-03-07 D. Zeb Rocklin , Shangnan Zhou , Kai Sun , Xiaoming Mao

A new strategy with bone tissue engineering by mesenchymal stem cell transplantation on titanium implant has been dawn attention. The surface scaffold properties of titanium surface play an important role in bone regenerative potential of…

Cell Behavior · Quantitative Biology 2010-05-03 Yukimichi Tamaki , Yu Kataoka , Takashi Miyazaki

In this letter, we investigate the geometrically tailorable elasticity in the twisting behavior of biomimetic scale-covered slender soft substrate. Motivated by our qualitative experiments showing a significant torsional rigidity increase,…

Soft Condensed Matter · Physics 2019-09-04 Hossein Ebrahimi , Hessein Ali , Ryan Alexander Horton , Jonathan Galvez , Ali Gordon , Ranajay Ghosh

Chirality, the property of asymmetry, is of great importance in biological and physical phenomena. This prospective offers an overview of the emerging field of chiral bioinspired plasmonics and metamaterials, aiming to uncover nature's…

Flexible mechanical structures can undergo large deformations under small loads, enabling large, complex, and nonlinear wave responses under finite-frequency driving. Here, we study a dynamically driven canonical flexible mechanical…

Soft Condensed Matter · Physics 2026-04-21 Neel Singh , Audrey A. Watkins , Giovanni Bordiga , Vincent Tournat , Katia Bertoldi , Zeb Rocklin

Active gels play an important role in biology and in inspiring biomimetic active materials, due to their ability to change shape, size and create their own morphology; the relevant mechanics behind these changes is driven by…

Soft Condensed Matter · Physics 2023-09-22 Anne Bernheim-Groswasser , Gefen Livne , Paola Nardinocchi , Filippo Recrosi , Luciano Teresi

Biological systems offer a great many examples of how sophisticated, highly adapted behavior can emerge from training. Here we discuss how training might be used to impart similarly adaptive properties in physical matter. As a special form…

Soft Condensed Matter · Physics 2024-03-12 Heinrich M. Jaeger , Arvind Murugan , Sidney R. Nagel

Protein-ligand binding is a fundamental biological process that is paramount to many other biological processes, such as signal transduction, metabolic pathways, enzyme construction, cell secretion, gene expression, etc. Accurate prediction…

Quantitative Methods · Quantitative Biology 2017-04-03 Zixuan Cang , Guo-Wei Wei

Biofilms are complex, self-organized consortia of microorganisms that produce a functional, protective matrix of biomolecules. Physically, the structure of a biofilm can be described as an entangled polymer network which grows and changes…

Biological Physics · Physics 2016-11-08 Marco G. Mazza

Architectural transformations play a key role in the evolution of complex systems, from design algorithms for metamaterials to flow and plasticity of disordered media. Here, we develop a general framework for the evolution of the linear…

Soft Condensed Matter · Physics 2020-02-20 Anne S. Meeussen , Erdal C. Oguz , Martin van Hecke , Yair Shokef

High strength and high toughness are usually mutually exclusive in engineering materials. Improving the toughness of strong but brittle materials like ceramics thus relies on the introduction of a metallic or polymeric ductile phase to…

A quantitative understanding of how cells interact with their extracellular matrix via molecular bonds is fundamental for many important processes in cell biology and engineering. In these interactions, the deformability of cells and matrix…

Biological Physics · Physics 2022-07-13 Qiangzeng Huang , Jizeng Wang

A 3D biomechanical dynamical model of human tongue is presented, which is elaborated to test in the future hypotheses about speech motor control. Tissue elastic properties are accounted for in Finite Element Modelling (FEM). The FEM mesh…

Medical Physics · Physics 2007-05-23 Jean-Michel Gerard , Pascal Perrier , Yohan Payan

Here we develop an approach to bio-structural robustness integrated with structure-function relationship in a unified conceptual and methodological framework, and envision its study using adequate computational and experimental methods. To…

Other Quantitative Biology · Quantitative Biology 2008-06-04 Nicanor I. Moldovan

Several biological tissues undergo changes in their geometry and in their bulk material properties by modelling and remodelling processes. Modelling synthesises tissue in some regions and removes tissue in others. Remodelling overwrites old…

Tissues and Organs · Quantitative Biology 2016-05-13 Pascal R. Buenzli

Mechanical metamaterials present a promising platform for seemingly impossible mechanics. They often require incompatibility of their elementary building blocks, yet a comprehensive understanding of its role remains elusive. Relying on an…

Soft Condensed Matter · Physics 2021-06-16 Ben Pisanty , Erdal C. Oguz , Cristiano Nisoli , Yair Shokef