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Modeling the behavior of coupled networks is challenging due to their intricate dynamics. For example in neuroscience, it is of critical importance to understand the relationship between the functional neural processes and anatomical…

Machine Learning · Computer Science 2021-04-20 Hongyuan You , Sikun Lin , Ambuj K. Singh

We present a new experimental-computational technology of inferring network models that predict the response of cells to perturbations and that may be useful in the design of combinatorial therapy against cancer. The experiments are…

Optimal block designs for additive models achieve their efficiency by dividing experimental units among relatively homogenous blocks and allocating treatments equally to blocks. Responses in many modern experiments, however, are drawn from…

Methodology · Statistics 2016-01-05 Stephen Bush , Katya Ruggiero

Complex networks are frequently employed to model physical or virtual complex systems. When certain entities exist across multiple systems simultaneously, unveiling their corresponding relationships across the networks becomes crucial. This…

Physics and Society · Physics 2025-04-16 Rui Tang , Ziyun Yong , Shuyu Jiang , Xingshu Chen , Yaofang Liu , Yi-Cheng Zhang , Gui-Quan Sun , Wei Wang

A networked dynamical system is composed of subsystems interconnected through prescribed interactions. In many engineering applications, however, one subsystem can also affect others through "unintended" interactions that can significantly…

Systems and Control · Electrical Eng. & Systems 2020-09-10 Yili Qian , Domitilla Del Vecchio

Modeling the interference effect is an important issue in the field of causal inference. Existing studies rely on explicit and often homogeneous assumptions regarding interference structures. In this paper, we introduce a low-rank and…

Methodology · Statistics 2024-10-31 Wei Zhang , Ying Yang , Fang Yao

Estimating causal effects has become an integral part of most applied fields. In this work we consider the violation of the classical no-interference assumption with units connected by a network. For tractability, we consider a known…

Machine Learning · Statistics 2025-03-05 Alexandre Belloni , Fei Fang , Alexander Volfovsky

Nowadays, in many scientific and industrial fields there is an increasing need for estimating treatment effects and answering causal questions. The key for addressing these problems is the wealth of observational data and the processes for…

Machine Learning · Statistics 2022-05-24 Niki Kiriakidou , Christos Diou

We propose a matching method that recovers direct treatment effects from randomized experiments where units are connected in an observed network, and units that share edges can potentially influence each others' outcomes. Traditional…

Combination therapy has shown to improve therapeutic efficacy while reducing side effects. Importantly, it has become an indispensable strategy to overcome resistance in antibiotics, anti-microbials, and anti-cancer drugs. Facing enormous…

Molecular Networks · Quantitative Biology 2020-04-24 Mostafa Karimi , Arman Hasanzadeh , Yang shen

Network data are observed in various applications where the individual entities of the system interact with or are connected to each other, and often these interactions are defined by their associated strength or importance. Clustering is a…

Methodology · Statistics 2025-06-02 Iuliia Promskaia , Adrian O'Hagan , Michael Fop

Randomized experiments are the gold standard for estimating treatment effects, yet network interference challenges the validity of traditional estimators by violating the stable unit treatment value assumption and introducing bias. While…

Methodology · Statistics 2024-09-02 Xin Lu , Hongzi Li , Hanzhong Liu

The structure of a bipartite interaction network can be described by providing a clustering for each of the two types of nodes. Such clusterings are outputted by fitting a Latent Block Model (LBM) on an observed network that comes from a…

Methodology · Statistics 2025-03-19 Emre Anakok , Pierre Barbillon , Colin Fontaine , Elisa Thebault

Network intervention problems often benefit from selecting a highly-connected node to perform interventions using these nodes, e.g. immunization. However, in many network contexts, the structure of network connections is unknown, leading to…

Social and Information Networks · Computer Science 2021-05-20 Vineet Kumar , David Krackhardt , Scott Feld

Randomized experiments are widely used to estimate causal effects across a variety of domains. However, classical causal inference approaches rely on critical independence assumptions that are violated by network interference, when the…

Methodology · Statistics 2022-10-18 Mayleen Cortez , Matthew Eichhorn , Christina Lee Yu

Computational methods in drug repositioning can help to conserve resources. In particular, methods based on biological networks are showing promise. Considering only the network topology and knowledge on drug target genes is not sufficient…

Molecular Networks · Quantitative Biology 2025-04-02 Atte Aalto , La Mi , Diego A. Blanco-Mora , Jorge Goncalves

We consider a setting where individuals interact in a network, each choosing actions which optimize utility as a function of neighbors' actions. A central authority aiming to maximize social welfare at equilibrium can intervene by paying…

Social and Information Networks · Computer Science 2020-07-14 William Brown , Utkarsh Patange

By leveraging information technologies, organizations now have the ability to design their communication networks and crowdsourcing platforms to pursue various performance goals, but existing research on network design does not account for…

Social and Information Networks · Computer Science 2013-08-15 Benjamin Lubin , Jesse Shore , Vatche Ishakian

A key topic in network science is the detection of intermediate or meso-scale structures. Community, core-periphery, disassortative and other partitions allow us to understand the organisation and function of large networks. In this work we…

Social and Information Networks · Computer Science 2024-07-16 Rudy Arthur

Treatment effect estimation can assist in effective decision-making in e-commerce, medicine, and education. One popular application of this estimation lies in the prediction of the impact of a treatment (e.g., a promotion) on an outcome…

Machine Learning · Computer Science 2023-09-26 Xiaofeng Lin , Guoxi Zhang , Xiaotian Lu , Han Bao , Koh Takeuchi , Hisashi Kashima
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