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Biomolecules that constitute life on Earth are chiral, but the precise mechanism by which homochirality emerged remains a mystery. In this work it is demonstrated that reactions of radical pairs, where one of the radical electron spins is…

Chemical Physics · Physics 2025-08-08 Thomas P Fay

Chirality occupies a central role in fields ranging from biological self-assembly to the design of optical metamaterials. The definition of chirality, as given by Lord Kelvin, associates chirality with the lack of mirror symmetry: the…

Soft Condensed Matter · Physics 2014-01-21 Efi Efrati , William T. M. Irvine

Results of recent experiment reinstate feasibility to the hypothesis that biomolecular homochirality originates from beta decay. Coupled with hints that this process occurred extraterrestrially suggests aluminum-26 as the most likely…

Cosmology and Nongalactic Astrophysics · Physics 2017-11-29 McCullen Sandora

It has been proposed that spin-polarized cosmic radiation can induce asymmetric changes in helical biopolymers that may account for the emergence of biological homochirality. The parity violation in the weak interaction has direct…

Earth and Planetary Astrophysics · Physics 2021-04-07 Noemie Globus , Anatoli Fedynitch , Roger D. Blandford

We describe circular polarization as a remote sensing diagnostic of chiral signatures which may be applied to Mars. The remarkable phenomenon of homochirality provides a unique biosignature which can be amenable to remote sensing through…

Earth and Planetary Astrophysics · Physics 2015-06-11 William Sparks , James H. Hough , Thomas A. Germer , Frank Robb , Ludmilla Kolokolova

The article seeks to formulate a synergetic law that is posited to be of common physicochemical and biological nature: an evolving system, possessing free energy and elements with chiral asymmetry may change the type of symmetry inside one…

Adaptation and Self-Organizing Systems · Physics 2012-12-10 Vsevolod A. Tverdislov

The probability that life spontaneously emerges in a suitable environment (abiogenesis) is one of the major unknowns in astrobiology. Assessing its value is impeded by the lack of an accepted theory for the origin of life, and is further…

Earth and Planetary Astrophysics · Physics 2023-05-10 Amedeo Balbi , Manasvi Lingam

The chiral puzzle of biological molecules is thought to be closely related to the origin of life and is still a mystery so far. Previously, we proposed a new model on the origin of life, Nebula-Relay hypothesis, which assumed that the life…

Popular Physics · Physics 2022-03-01 Lei Feng

I consider the microscopic mechanisms by which a particular left-right (L/R) asymmetry is generated at the organism level from the microscopic handedness of cytoskeletal molecules. In light of a fundamental symmetry principle, the typical…

Subcellular Processes · Quantitative Biology 2015-06-03 Christopher L. Henley

RNA in extant biological systems is homochiral; it consists exclusively of D-ribonucleotides rather than L-ribonucleotides. How the homochirality of RNA emerged is not known. Here, we use stochastic simulations to quantitatively explore the…

Biological Physics · Physics 2024-04-19 Gabin Laurent , Tobias Göppel , David Lacoste , Ulrich Gerland

We investigate the possibility that prebiotic homochirality can be achieved exclusively through chiral-selective reaction rate parameters without any other explicit mechanism for chiral bias. Specifically, we examine an open network of…

Biomolecules · Quantitative Biology 2015-06-03 Marcelo Gleiser , Bradley J. Nelson , Sara Imari Walker

The peptides in biosystems are homochiral polymers of L-amino acids, but razemisate slowly by an active isomerization kinetics. The chemical reactions in biosystems are, however, reversible and what racemisates the peptides at the water…

Soft Condensed Matter · Physics 2017-02-07 Søren Toxvaerd

NASA should design missions to Mars for the purpose of generating "Aha!" discoveries to jolt scientists contemplating the molecular origins of life. These missions should be designed with an understanding of the privileged chemistry that…

Instrumentation and Methods for Astrophysics · Physics 2020-09-03 Steven A. Benner , Elisa Biondi , Hyo-Joong Kim , Jan Špaček

Intimately connected to the rule of life, chirality remains a long-time fascination in biology, chemistry, physics and materials science. Chiral structures, e.g., nucleic acid and cholesteric phase developed from chiral molecules are common…

The emergence of biomolecular homochirality requires both an initial symmetry-breaking event and a mechanism to amplify and preserve a chiral imbalance. Magnetic minerals have been shown to function as chiral agents through the…

The colonization of Mars presents extraordinary challenges, including radiation exposure, low atmospheric pressure, and toxic regolith. Recent advancements in synthetic biology and genetic engineering offer unprecedented opportunities to…

Earth and Planetary Astrophysics · Physics 2025-04-01 Randall R. Correll , Simon P. Worden

Ocean worlds are considered as targets for life detection missions because they meet several key requirements for habitability. However, identifying potential life on other worlds requires observing clear and unambiguous biosignature…

Earth and Planetary Astrophysics · Physics 2026-05-18 Peter M. Higgins , Weibin Chen , Oliver Warr , Lucas M. Fifer , Wanying Kang , Charles S. Cockell , Barbara Sherwood Lollar

The study of origins of life on Earth and the search for life on other planets are closely linked. Prebiotic chemical scenarios can help prioritize planets as targets for the search for life as we know it and can provide informative priors…

Earth and Planetary Astrophysics · Physics 2021-08-20 Paul B Rimmer , Sukrit Ranjan , Sarah Rugheimer

Chirality, or handedness, is a topic that is common in biology and chemistry, yet is rarely discussed in physics courses. We provide a way of introducing the topic in classical physics, and demonstrate the merits of its inclusion - such as…

Popular Physics · Physics 2020-06-17 Chris L. Lin

We propose a new mechanism for the achievment of homochirality in life without any autocatalytic production process. Our model consists of a spontaneous production together with a recycling cross inhibition in a closed system. It is shown…

Chemical Physics · Physics 2009-11-13 Takeshi Sugimori , Hiroyuki Hyuga , Yukio Saito