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To understand the chirality selection in the biological organic system, a simple lattice model of chemical reaction with molecular diffusion is proposed and studied by Monte Carlo simulations. In addition to a simple stochastic process of…

Chemical Physics · Physics 2007-07-20 Yukio Saito , Hiroyuki Hyuga

The differences between uni-directional and bi-directional polymerization are considered. The uni-directional case is discussed in the framework of the RNA world. Similar to earlier models of this type, where polymerization was assumed to…

Biomolecules · Quantitative Biology 2007-05-23 M. Nilsson , A. Brandenburg , A. C. Andersen , S. Hoefner

Chirality, or handedness, is a geometrical property denoting a lack of mirror symmetry. Chirality is ubiquitous in nature and is associated with the non-reciprocal interactions observed in complex systems ranging from biomolecules to…

Quantum Physics · Physics 2024-08-08 Jonah S. Peter , Stefan Ostermann , Susanne F. Yelin

Pasteur has demonstrated that the chiral components in a racemic mixture can separate in homochiral crystals. But with a strong chiral discrimination the chiral components in a concentrated mixture can also phase separate into homochiral…

Biological Physics · Physics 2014-02-06 Soeren Toxvaerd

The complex physicochemical structures and chemical reactions in living organism have some common features: (1) The life processes take place in the cytosol in the cells, which, from a physicochemical point of view is an emulsion of…

Other Quantitative Biology · Quantitative Biology 2019-05-23 Søren Toxvaerd

An origin of Earth life on Mars would resolve significant inconsistencies between the inferred history of life and Earth's geologic history. Life as we know it utilizes amino acids, nucleic acids, and lipids for the metabolic,…

Earth and Planetary Astrophysics · Physics 2022-07-20 Christopher E. Carr

The emergence and spreading of chirality on the early Earth is considered by studying a set of reaction-diffusion equations based on a polymerization model. It is found that effective mixing of the early oceans is necessary to reach the…

Biomolecules · Quantitative Biology 2015-06-26 Tuomas Multamaki , Axel Brandenburg

In the laboratory, the photo-and thermochemical evolution of ices, made of simple molecules of astrophysical relevance, always leads to the formation of semi-refractory water-soluble organic residues. Targeted searches for specific…

Earth and Planetary Astrophysics · Physics 2019-02-14 Louis D'hendecourt , Paola Modica , Cornelia Meinert , Laurent Nahon , Uwe Meierhenrich

The question of the onset of the homochirality on prebiotic Earth still remains a fundamental question in the quest for the origin of life. Recent works in this field introduce the concept of recycling, rather than the traditional open-flow…

Molecular Networks · Quantitative Biology 2011-05-23 Raphael Plasson

Several aspects of mathematical astrobiology are discussed. It is argued that around the time of the origin of life the handedness of biomolecules must have established itself through an instability. Possible pathways of producing a certain…

Biomolecules · Quantitative Biology 2011-07-05 Axel Brandenburg

A mechanism for creating an enantioenrichment in the amino acids, the building blocks of the proteins, that involves global selection of one handedness by interactions between the amino acids and neutrinos from core-collapse supernovae is…

Biological Physics · Physics 2015-05-28 R. N. Boyd , T. Kajino , T. Onaka

Would another origin of life resemble Earth's biochemical use of amino acids? Here we review current knowledge at three levels: 1) Could other classes of chemical structure serve as building blocks for biopolymer structure and catalysis?…

Biomolecules · Quantitative Biology 2024-06-04 Sean M. Brown , Christopher Mayer-Bacon , Stephen Freeland

One of the longest standing open problems in science is how life arises from non-living matter. If it is possible to measure this transition in the lab, then it might be possible to understand the physical mechanisms by which the emergence…

Biomolecules · Quantitative Biology 2026-02-23 Sara Imari Walker

Amino acids occurring in proteins are, with rare exceptions, exclusively of the L-configuration. Among the many scenarios put forward to explain the origin of this chiral homogeneity (i.e., homochirality), one involves the asymmetric…

Astrophysics · Physics 2007-05-23 C. Cerf , A. Jorissen

The origin of chirality, closely related to the evolution of life on the earth, has long been debated. In 1991, Abdus Salam suggested a novel approach to achieve biomolecular homochirality by a phase transition. In his subsequent…

Biological Physics · Physics 2007-05-23 Fan Bai , Wenqing Wang

Most animal body plans have some degree of left-right asymmetry. This chirality at the tissue and organ level is often assumed to originate from the intrinsic handedness of biological molecules. How this handedness might be transferred from…

Tissues and Organs · Quantitative Biology 2017-08-30 Jeremy Hadidjojo , David K. Lubensky

A phase transition can drive the spontaneous emergence of chiral orders in crystals below a critical temperature. However, selecting either a right- or a left-handed phase with the aid of electromagnetic fields is challenging, particularly…

Materials Science · Physics 2025-03-11 Mauro Fava , Aldo H. Romero , Eric Bousquet

Chirality is at the origin of life and is ubiquitous in nature. An object is deemed chiral if it is non-superimposable with its own mirror image. This relates to how circularly polarized light interacts with such object, a circular…

Any search for present or past life beyond Earth should consider the initial processes and related environmental controls that might have led to its start. As on Earth, such an understanding lies well beyond how simple organic molecules…

Instrumentation and Methods for Astrophysics · Physics 2020-08-12 Timothy W. Lyons , Karyn Rogers , Ramanarayanan Krishnamurthy , Loren Williams , Simone Marchi , Edward Schwieterman , Noah Planavsky , Christopher Reinhard

As an attempt to understand the homochirality of organic molecules in life, a chemical reaction model is proposed where the production of chiral monomers from achiral substrate is catalyzed by the polymers of the same enatiomeric type. This…

Biological Physics · Physics 2007-07-20 Yukio Saito , Hiroyuki Hyuga