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This paper presents a novel approach for unsupervised domain adaptation (UDA) targeting H&E stained histology images. Existing adversarial domain adaptation methods may not effectively align different domains of multimodal distributions…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Ravi Kant Gupta , Shounak Das , Amit Sethi

In medical image segmentation, supervised deep networks' success comes at the cost of requiring abundant labeled data. While asking domain experts to annotate only one or a few of the cohort's images is feasible, annotating all available…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Devavrat Tomar , Behzad Bozorgtabar , Manana Lortkipanidze , Guillaume Vray , Mohammad Saeed Rad , Jean-Philippe Thiran

Continuous appearance shifts such as changes in weather and lighting conditions can impact the performance of deployed machine learning models. While unsupervised domain adaptation aims to address this challenge, current approaches do not…

Machine Learning · Statistics 2018-02-27 Markus Wulfmeier , Alex Bewley , Ingmar Posner

Data augmentation has proved extremely useful by increasing training data variance to alleviate overfitting and improve deep neural networks' generalization performance. In medical image analysis, a well-designed augmentation policy usually…

Computer Vision and Pattern Recognition · Computer Science 2021-03-31 Yunhe Gao , Zhiqiang Tang , Mu Zhou , Dimitris Metaxas

Machine learning (ML) algorithms are optimized for the distribution represented by the training data. For outlier data, they often deliver predictions with equal confidence, even though these should not be trusted. In order to deploy…

Image and Video Processing · Electrical Eng. & Systems 2021-03-17 Milda Pocevičiūtė , Gabriel Eilertsen , Claes Lundström

Staining is essential in cell imaging and medical diagnostics but poses significant challenges, including high cost, time consumption, labor intensity, and irreversible tissue alterations. Recent advances in deep learning have enabled…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Ziwang Xu , Lanqing Guo , Satoshi Tsutsui , Shuyan Zhang , Alex C. Kot , Bihan Wen

Methods for unsupervised domain adaptation (UDA) help to improve the performance of deep neural networks on unseen domains without any labeled data. Especially in medical disciplines such as histopathology, this is crucial since large…

Computer Vision and Pattern Recognition · Computer Science 2023-02-03 Kevin Thandiackal , Luigi Piccinelli , Pushpak Pati , Orcun Goksel

In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 Hongwei Li , Timo Loehr , Anjany Sekuboyina , Jianguo Zhang , Benedikt Wiestler , Bjoern Menze

Supervised deep learning algorithms have enabled significant performance gains in medical image classification tasks. But these methods rely on large labeled datasets that require resource-intensive expert annotation. Semi-supervised…

Image alignment across domains has recently become one of the realistic and popular topics in the research community. In this problem, a deep learning-based image alignment method is usually trained on an available largescale database.…

Computer Vision and Pattern Recognition · Computer Science 2019-06-03 Thanh-Dat Truong , Khoa Luu , Chi Nhan Duong , Ngan Le , Minh-Triet Tran

The presence and density of specific types of immune cells are important to understand a patient's immune response to cancer. However, immunofluorescence staining required to identify T cell subtypes is expensive, time-consuming, and rarely…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Georg Wölflein , In Hwa Um , David J Harrison , Ognjen Arandjelović

Differences in staining and imaging procedures can cause significant color variations in histopathology images, leading to poor generalization when deploying deep-learning models trained from a different data source. Various color…

Chemical staining methods are dependable but require extensive time, expensive chemicals, and raise environmental concerns. These challenges highlight the need for alternative solutions like virtual staining, which accelerates the…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Mehdi Ounissi , Ilias Sarbout , Jean-Pierre Hugot , Christine Martinez-Vinson , Dominique Berrebi , Daniel Racoceanu

Visual Domain Adaptation is a problem of immense importance in computer vision. Previous approaches showcase the inability of even deep neural networks to learn informative representations across domain shift. This problem is more severe…

Computer Vision and Pattern Recognition · Computer Science 2018-04-03 Swami Sankaranarayanan , Yogesh Balaji , Arpit Jain , Ser Nam Lim , Rama Chellappa

The visual attributes of cells, such as the nuclear morphology and chromatin openness, are critical for histopathology image analysis. By learning cell-level visual representation, we can obtain a rich mix of features that are highly…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Bo Hu , Ye Tang , Eric I-Chao Chang , Yubo Fan , Maode Lai , Yan Xu

Domain adaptation is widely used in learning problems lacking labels. Recent studies show that deep adversarial domain adaptation models can make markable improvements in performance, which include symmetric and asymmetric architectures.…

Computer Vision and Pattern Recognition · Computer Science 2019-09-19 Guanyu Cai , Yuqin Wang , Mengchu Zhou , Lianghua He

In this paper, we make two contributions to unsupervised domain adaptation (UDA) using the convolutional neural network (CNN). First, our approach transfers knowledge in all the convolutional layers through attention alignment. Most…

Computer Vision and Pattern Recognition · Computer Science 2018-08-14 Guoliang Kang , Liang Zheng , Yan Yan , Yi Yang

Unsupervised learning methods based on contrastive learning have drawn increasing attention and achieved promising results. Most of them aim to learn representations invariant to instance-level variations, which are provided by different…

Computer Vision and Pattern Recognition · Computer Science 2020-11-04 Feng Wang , Huaping Liu , Di Guo , Fuchun Sun

Recent advances in generative adversarial networks (GANs) have shown remarkable progress in generating high-quality images. However, this gain in performance depends on the availability of a large amount of training data. In limited data…

Computer Vision and Pattern Recognition · Computer Science 2021-09-22 Puneet Mangla , Nupur Kumari , Mayank Singh , Balaji Krishnamurthy , Vineeth N Balasubramanian

Deep learning is widely applied in computer-aided pathological diagnosis, which alleviates the pathologist workload and provide timely clinical analysis. However, most models generally require large-scale annotated data for training, which…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Zeyu Liu , Tianyi Zhang , Yufang He , Yunlu Feng , Yu Zhao , Guanglei Zhang
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