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Computational histopathology image diagnosis becomes increasingly popular and important, where images are segmented or classified for disease diagnosis by computers. While pathologists do not struggle with color variations in slides,…

Image and Video Processing · Electrical Eng. & Systems 2020-07-27 Hanwen Liang , Konstantinos N. Plataniotis , Xingyu Li

Recently, generative adversarial networks exhibited excellent performances in semi-supervised image analysis scenarios. In this paper, we go even further by proposing a fully unsupervised approach for segmentation applications with prior…

Computer Vision and Pattern Recognition · Computer Science 2018-08-02 Michael Gadermayr , Laxmi Gupta , Barbara M. Klinkhammer , Peter Boor , Dorit Merhof

Automatic and accurate Gleason grading of histopathology tissue slides is crucial for prostate cancer diagnosis, treatment, and prognosis. Usually, histopathology tissue slides from different institutions show heterogeneous appearances…

Computer Vision and Pattern Recognition · Computer Science 2018-06-08 Jian Ren , Ilker Hacihaliloglu , Eric A. Singer , David J. Foran , Xin Qi

Models capable of leveraging unlabelled data are crucial in overcoming large distribution gaps between the acquired datasets across different imaging devices and configurations. In this regard, self-training techniques based on…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Negin Ghamsarian , Javier Gamazo Tejero , Pablo Márquez Neila , Sebastian Wolf , Martin Zinkernagel , Klaus Schoeffmann , Raphael Sznitman

Recent works showed that Generative Adversarial Networks (GANs) can be successfully applied in unsupervised domain adaptation, where, given a labeled source dataset and an unlabeled target dataset, the goal is to train powerful classifiers…

Computer Vision and Pattern Recognition · Computer Science 2018-05-07 Riccardo Volpi , Pietro Morerio , Silvio Savarese , Vittorio Murino

Suboptimal generalization of machine learning models on unseen data is a key challenge which hampers the clinical applicability of such models to medical imaging. Although various methods such as domain adaptation and domain generalization…

Image and Video Processing · Electrical Eng. & Systems 2021-08-04 Rikiya Yamashita , Jin Long , Snikitha Banda , Jeanne Shen , Daniel L. Rubin

While deep neural networks have achieved remarkable success in various computer vision tasks, they often fail to generalize to new domains and subtle variations of input images. Several defenses have been proposed to improve the robustness…

Computer Vision and Pattern Recognition · Computer Science 2021-09-08 Omid Poursaeed , Tianxing Jiang , Harry Yang , Serge Belongie , SerNam Lim

Despite notable advancements, the integration of deep learning (DL) techniques into impactful clinical applications, particularly in the realm of digital histopathology, has been hindered by challenges associated with achieving robust…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Sebastian Doerrich , Francesco Di Salvo , Christian Ledig

Performance of deep learning algorithms decreases drastically if the data distributions of the training and testing sets are different. Due to variations in staining protocols, reagent brands, and habits of technicians, color variation in…

Computer Vision and Pattern Recognition · Computer Science 2020-12-01 Abhijeet Patil , Mohd. Talha , Aniket Bhatia , Nikhil Cherian Kurian , Sammed Mangale , Sunil Patel , Amit Sethi

Whole Slide Images (WSIs) in digital pathology are used to diagnose cancer subtypes. The difference in procedures to acquire WSIs at various trial sites gives rise to variability in the histopathology images, thus making consistent…

Image and Video Processing · Electrical Eng. & Systems 2022-04-07 Milad Sikaroudi , Shahryar Rahnamayan , H. R. Tizhoosh

It's useful to automatically transform an image from its original form to some synthetic form (style, partial contents, etc.), while keeping the original structure or semantics. We define this requirement as the "image-to-image translation"…

Computer Vision and Pattern Recognition · Computer Science 2017-01-11 Hao Dong , Paarth Neekhara , Chao Wu , Yike Guo

Virtual staining leverages computer-aided techniques to transfer the style of histochemically stained tissue samples to other staining types. In virtual staining of pathological images, maintaining strict structural consistency is crucial,…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Bing Xiong , Yue Peng , RanRan Zhang , Fuqiang Chen , JiaYe He , Wenjian Qin

Unsupervised domain adaption aims to learn a powerful classifier for the target domain given a labeled source data set and an unlabeled target data set. To alleviate the effect of `domain shift', the major challenge in domain adaptation,…

Computer Vision and Pattern Recognition · Computer Science 2018-12-03 Yexun Zhang , Ya Zhang , Yanfeng Wang , Qi Tian

We propose a two-step domain shift-invariant mitosis cell detection method based on Faster RCNN and a convolutional neural network (CNN). We generate various domain-shifted versions of existing histopathology images using a stain…

Computer Vision and Pattern Recognition · Computer Science 2021-09-29 Ramin Nateghi , Fattaneh Pourakpour

Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…

Image and Video Processing · Electrical Eng. & Systems 2023-08-09 Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

Color inconsistency is an inevitable challenge in computational pathology, which generally happens because of stain intensity variations or sections scanned by different scanners. It harms the pathological image analysis methods, especially…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Bingchao Zhao , Jiatai Lin , Changhong Liang , Zongjian Yi , Xin Chen , Bingbing Li , Weihao Qiu , Danyi Li , Li Liang , Chu Han , Zaiyi Liu

Stain variations often decrease the generalization ability of deep learning based approaches in digital histopathology analysis. Two separate proposals, namely stain normalization (SN) and stain augmentation (SA), have been spotlighted to…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Yiqing Shen , Yulin Luo , Dinggang Shen , Jing Ke

Stain variation is a phenomenon observed when distinct pathology laboratories stain tissue slides that exhibit similar but not identical color appearance. Due to this color shift between laboratories, convolutional neural networks (CNNs)…

Computer Vision and Pattern Recognition · Computer Science 2020-04-16 David Tellez , Geert Litjens , Peter Bandi , Wouter Bulten , John-Melle Bokhorst , Francesco Ciompi , Jeroen van der Laak

Deep learning techniques, especially Generative Adversarial Networks (GANs) have significantly improved image inpainting and image-to-image translation tasks over the past few years. To the best of our knowledge, the problem of combining…

Image and Video Processing · Electrical Eng. & Systems 2022-06-23 Aref Abedjooy , Mehran Ebrahimi

Acquisition of data in task-specific applications of machine learning like plant disease recognition is a costly endeavor owing to the requirements of professional human diligence and time constraints. In this paper, we present a simple…

Computer Vision and Pattern Recognition · Computer Science 2019-09-27 Haseeb Nazki , Sook Yoon , Alvaro Fuentes , Dong Sun Park