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The annual occurrence of many infectious diseases remains a constant burden to public health systems. The seasonal patterns in respiratory disease incidence observed in temperate regions have been attributed to the impact of environmental…

Populations and Evolution · Quantitative Biology 2013-11-13 Marguerite Robinson , Yannis Drossinos , Nikolaos I. Stilianakis

Risk-driven behavior provides a feedback mechanism through which individuals both shape and are collectively affected by an epidemic. We introduce a general and flexible compartmental model to study the effect of heterogeneity in the…

Host mobility plays a fundamental role in the spatial spread of infectious diseases. Previous theoretical works based on the integration of network theory into the metapopulation framework have shown that the heterogeneities that…

Physics and Society · Physics 2013-09-26 Chiara Poletto , Michele Tizzoni , Vittoria Colizza

Daily variation in human mobility modulates the speed and severity of emerging outbreaks, yet most epidemiological studies assume static contact patterns. With a highly mobile population exceeding 24 million people, Shanghai, China is a…

Social and Information Networks · Computer Science 2018-09-17 Zhanwei Du , Spencer J Fox , Petter Holme , Jiming Liu , Alison P. Galvani , Lauren Ancel Meyers

The spreading of epidemics is very much determined by the structure of the contact network, which may be impacted by the mobility dynamics of the individuals themselves. In confined scenarios where a small, closed population spends most of…

Physics and Society · Physics 2018-05-09 Clara Granell , Peter J. Mucha

We study the effect of the connectivity pattern of complex networks on the propagation dynamics of epidemics. The growth time scale of outbreaks is inversely proportional to the network degree fluctuations, signaling that epidemics spread…

Disordered Systems and Neural Networks · Physics 2009-11-10 Marc Barthelemy , Alain Barrat , Romualdo Pastor-Satorras , Alessandro Vespignani

Human pathogens transmitted through environmental pathways are subject to stress and pressures outside of the host. These pressures may cause pathogen pathovars to diverge in their environmental persistence and their infectivity on an…

Populations and Evolution · Quantitative Biology 2018-02-16 Andrew F. Brouwer , Marisa C. Eisenberg , Nancy G. Love , Joseph N. S. Eisenberg

Most previous studies of epidemic dynamics on complex networks suppose that the disease will eventually stabilize at either a disease-free state or an endemic one. In reality, however, some epidemics always exhibit sporadic and recurrent…

Physics and Society · Physics 2013-11-19 Xiao-Long Peng , Michael Small , Xin-Jian Xu , Xinchu Fu

Mitigation measures are essential for controlling the spread of infectious diseases during pandemics and epidemics, but they impose considerable societal, individual, and economic costs. We developed a general optimization framework to…

Populations and Evolution · Quantitative Biology 2025-12-15 Laura Müller , Fabio Sartori , Jonas Dehning , Maximilian F. Eggl , Viola Priesemann

The shape of an epidemic wave in simple epidemic models applies to a homogeneous distribution of infected people in the population. In large inhomogeneous systems, at country-scale for instance, the wave shape is similar except for the…

Chemical Physics · Physics 2022-11-21 L. Vanel

We combine a pedestrian dynamics model with a contact tracing method to simulate the initial spreading of a highly infectious airborne disease in a confined environment. We focus on a medium size population (up to 1000 people) with a small…

Physics and Society · Physics 2020-04-22 Krithika Rathinakumar , Annalisa Quaini

Increasing the infection risk early in an epidemic is individually and socially optimal under some parameter values. The reason is that the early patients recover or die before the peak of the epidemic, which flattens the peak. This…

Populations and Evolution · Quantitative Biology 2020-04-28 Sander Heinsalu

In contrast to previous common wisdom that epidemic activity in heterogeneous networks is dominated by the hubs with the largest number of connections, recent research has pointed out the role that the innermost, dense core of the network…

Physics and Society · Physics 2012-05-04 Claudio Castellano , Romualdo Pastor-Satorras

The spread of an infection on a real-world social network is determined by the interplay of two processes: the dynamics of the network, whose structure changes over time according to the encounters between individuals, and the dynamics on…

Physics and Society · Physics 2015-10-28 Lorenzo Coviello , Massimo Franceschetti , Manuel Garcia-Herranz , Iyad Rahwan

The impact that information diffusion has on epidemic spreading has recently attracted much attention. As a disease begins to spread in the population, information about the disease is transmitted to others, which in turn has an effect on…

Physics and Society · Physics 2015-06-15 Xiu-Xiu Zhan , Chuang Liu , Ge Zhou , Zi-Ke Zhang , Gui-Quan Sun , Jonathan J. H. Zhu

There is a rich history of models for the interaction of a biological contagion like influenza with the spread of related information such as an influenza vaccination campaign. Recent work on the spread of interacting contagions on networks…

Physics and Society · Physics 2020-09-02 Laurent Hébert-Dufresne , Dina Mistry , Benjamin M. Althouse

The effect of spatial correlations on the spread of infectious diseases was investigated using a stochastic SIR (Susceptible-Infective-Recovered) model on complex networks. It was found that in addition to the reduction of the effective…

Populations and Evolution · Quantitative Biology 2007-05-23 J. Verdasca , M. M. Telo da Gama , A. Nunes , N. R. Bernardino , J. M. Pacheco , M. C. Gomes

Rapidly mutating pathogens may be able to persist in the population and reach an endemic equilibrium by escaping hosts' acquired immunity. For such diseases, multiple biological, environmental and population-level mechanisms determine the…

Physics and Society · Physics 2019-02-07 Alberto Aleta , Andreia N. S. Hisi , Sandro Meloni , Chiara Poletto , Vittoria Colizza , Yamir Moreno

The compact city, as a sustainable concept, is intended to augment the efficiency of urban function. However, previous studies have concentrated more on morphology than on structure. The present study focuses on urban structural elements,…

General Economics · Economics 2019-08-16 Weipan Xu , Haohui'Caron' Chen , Enrique Frias-Martinez , Manuel Cebrian , Xun Li

The symptoms of many infectious diseases influence their host to withdraw from social activity limiting their own potential to spread. Successful transmission therefore requires the onset of infectiousness to coincide with a time when its…

Populations and Evolution · Quantitative Biology 2017-07-27 Ewan Colman , Kristen Spies , Shweta Bansal