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Mapping clinical documents to standardised clinical vocabularies is an important task, as it provides structured data for information retrieval and analysis, which is essential to clinical research, hospital administration and improving…

Computation and Language · Computer Science 2025-09-15 Mingyang Li , Viktor Schlegel , Tingting Mu , Warren Del-Pinto , Goran Nenadic

Objectives: Administrative data is commonly used to inform chronic disease prevalence and support health informatics research. This study assessed the validity of coding comorbidity in the International Classification of Diseases, 10th…

Quantitative Methods · Quantitative Biology 2025-04-02 Jie Pan , Seungwon Lee , Cheligeer Cheligeer , Bing Li , Guosong Wu , Catherine A Eastwood , Yuan Xu , Hude Quan

Although the International Classification of Diseases (ICD) has been adopted worldwide, manually assigning ICD codes to clinical text is time-consuming, error-prone, and expensive, motivating the development of automated approaches. This…

Computation and Language · Computer Science 2024-02-06 Gonçalo Gomes , Isabel Coutinho , Bruno Martins

Healthcare clinics regularly encounter dynamic data that changes due to variations in patient populations, treatment policies, medical devices, and emerging disease patterns. Deep learning models can suffer from catastrophic forgetting when…

Machine Learning · Computer Science 2023-11-09 Amritpal Singh , Mustafa Burak Gurbuz , Shiva Souhith Gantha , Prahlad Jasti

With increasing and extensive use of electronic health records, clinicians are often under time pressure when they need to retrieve important information efficiently among large amounts of patients' health records in clinics. While a search…

Information Retrieval · Computer Science 2020-08-05 Zhiyun Ren , Bo Peng , Titus K. Schleyer , Xia Ning

International Classification of Diseases (ICD) is a set of classification codes for medical records. Automated ICD coding, which assigns unique International Classification of Diseases codes with each medical record, is widely used recently…

Artificial Intelligence · Computer Science 2022-12-12 Shi Wang , Daniel Tang , Luchen Zhang , Huilin Li , Ding Han

Clinical reasoning agents based on large language models (LLMs) aim to automate tasks such as intensive care unit (ICU) monitoring and patient state tracking from electronic health records (EHRs). Existing systems typically rely on manually…

Artificial Intelligence · Computer Science 2026-05-12 Timothy Ossowski , Xinchi Liu , Danyal Maqbool , Vaibhav Dhanuka , Sheng Zhang , Hoifung Poon , Majid Afshar , Tyler Bradshaw , Junjie Hu

Availability of diagnostic codes in Electronic Health Records (EHRs) is crucial for patient care as well as reimbursement purposes. However, entering them in the EHR is tedious, and some clinical codes may be overlooked. Given an…

Machine Learning · Computer Science 2023-05-10 Tsvetan R. Yordanov , Ameen Abu-Hanna , Anita CJ Ravelli , Iacopo Vagliano

Coding morbidity data using international standard diagnostic classifications is increasingly important and still challenging. Clinical coders and physicians assign codes to patient episodes based on their interpretation of case notes or…

Other Computer Science · Computer Science 2025-03-10 Elena Cardillo , Lucilla Frattura

Information extraction from textual documents such as hospital records and healthrelated user discussions has become a topic of intense interest. The task of medical concept coding is to map a variable length text to medical concepts and…

Computation and Language · Computer Science 2018-05-03 Elena Tutubalina , Zulfat Miftahutdinov

Automatic International Classification of Diseases (ICD) coding aims to assign multiple ICD codes to a medical note with an average of 3,000+ tokens. This task is challenging due to the high-dimensional space of multi-label assignment…

Computation and Language · Computer Science 2022-11-30 Zhichao Yang , Sunjae Kwon , Zonghai Yao , Hong Yu

Clinical trials constitute a critical yet exceptionally challenging and costly stage of drug development (\$2.6B per drug), where protocols are encoded as complex natural language documents, motivating the use of AI systems beyond manual…

Artificial Intelligence · Computer Science 2026-04-06 Sixue Xing , Kerui Wu , Xuanye Xia , Meng Jiang , Jintai Chen , Tianfan Fu

While the ICD code assignment problem has been widely studied, most works have focused on post-discharge document classification. Models for early forecasting of this information could be used for identifying health risks, suggesting…

Machine Learning · Computer Science 2025-08-18 Cindy Shih-Ting Huang , Clarence Boon Liang Ng , Marek Rei

ICD(International Classification of Diseases) coding involves assigning ICD codes to patients visit based on their medical notes. ICD coding is a challenging multilabel text classification problem due to noisy medical document inputs.…

Computation and Language · Computer Science 2024-09-04 Bin Zhang , Junli Wang

In order to submit a claim to insurance companies, a doctor needs to code a patient encounter with both the diagnosis (ICDs) and procedures performed (CPTs) in an Electronic Health Record (EHR). Identifying and applying relevant procedures…

Machine Learning · Statistics 2021-12-30 Hasham Ul Haq , Rameel Ahmad , Sibt Ul Hussain

Medical coding is a complex task, requiring assignment of a subset of over 72,000 ICD codes to a patient's notes. Modern natural language processing approaches to these tasks have been challenged by the length of the input and size of the…

Machine Learning · Computer Science 2022-08-17 Jay DeYoung , Han-Chin Shing , Luyang Kong , Christopher Winestock , Chaitanya Shivade

In medical coding, experts map unstructured clinical notes to alphanumeric codes for diagnoses and procedures. We introduce Code Like Humans: a new agentic framework for medical coding with large language models. It implements official…

Artificial Intelligence · Computer Science 2025-10-09 Andreas Motzfeldt , Joakim Edin , Casper L. Christensen , Christian Hardmeier , Lars Maaløe , Anna Rogers

Deep learning has the potential to automate many clinically useful tasks in medical imaging. However translation of deep learning into clinical practice has been hindered by issues such as lack of the transparency and interpretability in…

Image and Video Processing · Electrical Eng. & Systems 2022-05-04 Charles Lu , Andreanne Lemay , Ken Chang , Katharina Hoebel , Jayashree Kalpathy-Cramer

Accurately labeling biomedical data presents a challenge. Traditional semi-supervised learning methods often under-utilize available unlabeled data. To address this, we propose a novel reliability-based training data cleaning method…

Machine Learning · Computer Science 2023-09-15 Xianghao Zhan , Qinmei Xu , Yuanning Zheng , Guangming Lu , Olivier Gevaert

This research paper outlines the development and implementation of a novel Clinical Decision Support System (CDSS) that integrates AI predictive modeling with medical knowledge bases. It utilizes the quantifiable information elements in lab…

Artificial Intelligence · Computer Science 2026-03-17 Muhammad Hammad Maqsood , Mubashir Sajid , Khubaib Ahmed , Muhammad Usamah Shahid , Muddassar Farooq