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Large language models (LLMs) excel at a range of tasks through in-context learning (ICL), where only a few task examples guide their predictions. However, prior research highlights that LLMs often overlook input-label mapping information in…

Computation and Language · Computer Science 2025-06-10 Keqin Peng , Liang Ding , Yuanxin Ouyang , Meng Fang , Yancheng Yuan , Dacheng Tao

Objective: Electronic health records (EHR) data are prone to missingness and errors. Previously, we devised an "enriched" chart review protocol where a "roadmap" of auxiliary diagnoses (anchors) was used to recover missing values in EHR…

Machine Learning · Computer Science 2025-10-07 Sarah C. Lotspeich , Abbey Collins , Brian J. Wells , Ashish K. Khanna , Joseph Rigdon , Lucy D'Agostino McGowan

Within the intensive care unit (ICU), a wealth of patient data, including clinical measurements and clinical notes, is readily available. This data is a valuable resource for comprehending patient health and informing medical decisions, but…

Machine Learning · Computer Science 2023-12-13 Ryan King , Tianbao Yang , Bobak Mortazavi

When dealing with clinical text classification on a small dataset recent studies have confirmed that a well-tuned multilayer perceptron outperforms other generative classifiers, including deep learning ones. To increase the performance of…

Machine Learning · Computer Science 2022-09-27 Thanh-Dung Le , Rita Noumeir , Jerome Rambaud , Guillaume Sans , Philippe Jouvet

Linking clinical narratives to standardized vocabularies and coding systems is a key component of unlocking the information in medical text for analysis. However, many domains of medical concepts lack well-developed terminologies that can…

Computation and Language · Computer Science 2021-03-11 Denis Newman-Griffis , Eric Fosler-Lussier

Objective:Develop and validate an algorithm for analyzing the layout of PDF clinical documents to improve the performance of downstream natural language processing tasks. Materials and Methods: We designed an algorithm to process clinical…

Computation and Language · Computer Science 2023-05-24 Christel Gérardin , Perceval Wajsbürt , Basile Dura , Alice Calliger , Alexandre Moucher , Xavier Tannier , Romain Bey

Drug repurposing is an effective strategy to identify new uses for existing drugs, providing the quickest possible transition from bench to bedside. Existing methods for drug repurposing that mainly focus on pre-clinical information may…

Applications · Statistics 2021-04-14 Ruoqi Liu , Lai Wei , Ping Zhang

Most clinical AI systems operate as prediction engines -- producing labels or risk scores -- yet real clinical reasoning is a time-bounded, sequential control problem under uncertainty. Clinicians interleave information gathering with…

Artificial Intelligence · Computer Science 2026-01-21 Dipayan Sengupta , Saumya Panda

This paper presents a novel positive and negative set selection strategy for contrastive learning of medical images based on labels that can be extracted from clinical data. In the medical field, there exists a variety of labels for data…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Kiran Kokilepersaud , Stephanie Trejo Corona , Mohit Prabhushankar , Ghassan AlRegib , Charles Wykoff

Clinical diagnosis is a highly specialized discipline requiring both domain expertise and strict adherence to rigorous guidelines. While current AI-driven medical research predominantly focuses on knowledge graphs or natural text…

Machine Learning · Computer Science 2025-12-12 Haolin Li , Tianjie Dai , Zhe Chen , Siyuan Du , Jiangchao Yao , Ya Zhang , Yanfeng Wang

This paper achieves state of the art results for the ICD code prediction task using the MIMIC-III dataset. This was achieved through the use of Clinical BERT (Alsentzer et al., 2019). embeddings and text augmentation and label balancing to…

Computation and Language · Computer Science 2020-08-25 Brent Biseda , Gaurav Desai , Haifeng Lin , Anish Philip

Clinical trials are critical for drug development. Constructing the appropriate eligibility criteria (i.e., the inclusion/exclusion criteria for patient recruitment) is essential for the trial's success. Proper design of clinical trial…

Computation and Language · Computer Science 2023-10-10 Zifeng Wang , Cao Xiao , Jimeng Sun

Machine learning models that utilize patient data across time (rather than just the most recent measurements) have increased performance for many risk stratification tasks in the intensive care unit. However, many of these models and their…

Machine Learning · Computer Science 2021-09-24 Nari Johnson , Sonali Parbhoo , Andrew Slavin Ross , Finale Doshi-Velez

We present a system that uses a learned autocompletion mechanism to facilitate rapid creation of semi-structured clinical documentation. We dynamically suggest relevant clinical concepts as a doctor drafts a note by leveraging features from…

Machine Learning · Computer Science 2020-07-31 Divya Gopinath , Monica Agrawal , Luke Murray , Steven Horng , David Karger , David Sontag

We propose a method to teach multiple large language models (LLM) to collaborate by interleaving their generations at the token level. We model the decision of which LLM generates the next token as a latent variable. By optimizing the…

Computation and Language · Computer Science 2024-08-28 Shannon Zejiang Shen , Hunter Lang , Bailin Wang , Yoon Kim , David Sontag

Machine learning-aided clinical decision support has the potential to significantly improve patient care. However, existing efforts in this domain for principled quantification of uncertainty have largely been limited to applications of…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 L. Julian Lechuga Lopez , Tim G. J. Rudner , Farah E. Shamout

Class-incremental learning (CIL) in medical image-guided diagnosis requires retaining prior diagnostic knowledge while adapting to newly emerging disease categories, which is critical for scalable clinical deployment. This problem is…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Xinyao Wu , Zhe Xu , Cheng Chen , Jiawei Ma , Yefeng Zheng , Raymond Kai-yu Tong

Using machine learning in clinical practice poses hard requirements on explainability, reliability, replicability and robustness of these systems. Therefore, developing reliable software for monitoring critically ill patients requires close…

Software Engineering · Computer Science 2021-03-16 Miroslaw Staron , Helena Odenstedt Hergés , Silvana Naredi , Linda Block , Ali El-Merhi , Richard Vithal , Mikael Elam

Machine learning in medical imaging during clinical routine is impaired by changes in scanner protocols, hardware, or policies resulting in a heterogeneous set of acquisition settings. When training a deep learning model on an initial…

Computer Vision and Pattern Recognition · Computer Science 2022-03-16 Matthias Perkonigg , Johannes Hofmanninger , Christian Herold , Helmut Prosch , Georg Langs

Predicting whether a treatment leads to meaningful improvement is a central challenge in personalized medicine, particularly when disease progression manifests as subtle visual changes over time. While data-driven deep learning (DL) offers…

Image and Video Processing · Electrical Eng. & Systems 2025-11-21 Jana Armouti , Nikhil Madaan , Rohan Panda , Tom Fox , Laura Hutchins , Amita Krishnan , Ricardo Rodriguez , Bennett DeBoisblanc , Deva Ramanan , John Galeotti , Gautam Gare
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