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The brain is a high-dimensional directional network system consisting of many regions as network nodes that influence each other. The directional influence from one region to another is referred to as directional connectivity. Epilepsy is a…

Applications · Statistics 2022-08-18 Yaotian Wang , Guofen Yan , Seiji Tanabe , Chang-Chia Liu , Shayan Moosa , Mark S. Quigg , Tingting Zhang

Information transmission in the human brain is a fundamentally dynamic network process. In partial epilepsy, this process is perturbed and highly synchronous seizures originate in a local network, the so-called epileptogenic zone (EZ),…

Neurons and Cognition · Quantitative Biology 2019-06-19 Simona Olmi , Spase Petkoski , Maxime Guye , Fabrice Bartolomei , Viktor Jirsa

In this paper, we developed a model-based and a data-driven estimator for directed information (DI) to infer the causal connectivity graph between electrocorticographic (ECoG) signals recorded from brain and to identify the seizure onset…

Neurons and Cognition · Quantitative Biology 2016-11-03 Rakesh Malladi , Giridhar Kalamangalam , Nitin Tandon , Behnaam Aazhang

An ability to map seizure-generating brain tissue, i.e., the seizure onset zone (SOZ), without recording actual seizures could reduce the duration of invasive EEG monitoring for patients with drug-resistant epilepsy. A widely-adopted…

Epilepsy which is characterized by seizures is studied using EEG signals by recording the electrical activity of the brain. Different types of communication between different parts of the brain are characterized by many state of the art…

Machine Learning · Computer Science 2020-09-29 Mohammad Mansour , Fouad Khnaisser , Hmayag Partamian

Neural network oscillations are a fundamental mechanism for cognition, perception and consciousness. Consequently, perturbations of network activity play an important role in the pathophysiology of brain disorders. When structural…

Neurons and Cognition · Quantitative Biology 2016-04-29 Timothée Proix , Fabrice Bartolomei , Maxime Guye , Viktor K. Jirsa

We assess electrical brain dynamics before, during, and after one-hundred human epileptic seizures with different anatomical onset locations by statistical and spectral properties of functionally defined networks. We observe a concave-like…

Neurons and Cognition · Quantitative Biology 2013-11-25 Kaspar A. Schindler , Stephan Bialonski , Marie-Therese Horstmann , Christian E. Elger , Klaus Lehnertz

Epilepsy is one of the most common neurological disorders, often requiring surgical intervention when medication fails to control seizures. For effective surgical outcomes, precise localisation of the epileptogenic focus - often…

Machine Learning · Computer Science 2024-08-28 Jamie Norris , Aswin Chari , Dorien van Blooijs , Gerald Cooray , Karl Friston , Martin Tisdall , Richard Rosch

Epilepsy is one of the most occurring neurological disease globally emerged back in 4000 BC. It is affecting around 50 million people of all ages these days. The trait of this disease is recurrent seizures. In the past few decades, the…

Machine Learning · Computer Science 2021-11-08 Virender Ranga , Shivam Gupta , Jyoti Meena , Priyansh Agrawal

Epilepsy is the fourth most common neurological disorder, affecting about 1% of the population at all ages. As many as 60% of people with epilepsy experience focal seizures which originate in a certain brain area and are limited to part of…

Machine Learning · Computer Science 2019-03-20 Diyuan Lu , Jochen Triesch

The electrical stimulation to the seizure onset zone (SOZ) serves as an efficient approach to seizure suppression. Recently, seizure dynamics have gained widespread attendance in its network propagation mechanisms. Compared with the direct…

Neurons and Cognition · Quantitative Biology 2024-06-17 Zhichao Liang , Guanyi Zhao , Yinuo Zhang , Weiting Sun , Jingzhe Lin , Jialin Wang , Quanying Liu

Neural oscillations are considered to be brain-specific signatures of information processing and communication in the brain. They also reflect pathological brain activity in neurological disorders, thus offering a basis for diagnoses and…

Neurons and Cognition · Quantitative Biology 2023-10-23 Tena Dubcek , Debora Ledergerber , Jana Thomann , Giovanna Aiello , Marc Serra-Garcia , Lukas Imbach , Rafael Polania

Accurate localization of the seizure onset zone (SOZ) from intracranial EEG (iEEG) is essential for epilepsy surgery but is challenged by complex spatiotemporal seizure dynamics. We propose SpaTeoGL, a spatiotemporal graph learning…

Machine Learning · Computer Science 2026-02-13 Elham Rostami , Aref Einizade , Taous-Meriem Laleg-Kirati

In this study, we present a criterion based on the analysis of EEG signals through the mean of the conventional power spectral density (PSD) in the aim to localize and detect the epileptic area of the brain. Firstly, as the EEG signals are…

Applications · Statistics 2016-10-31 Mahamat Ali Issaka , Ali S. Dabye , Lamine Gueye

Identifying preictal states -- periods during which seizures are more likely to occur -- remains a central challenge in clinical computational neuroscience. In this study, we introduce a novel framework that embeds functional brain…

Neurons and Cognition · Quantitative Biology 2025-05-21 Steven Rico-Aparicio , Martin Guillemaud , Alice Longhena , Vincent Navarro , Louis Cousyn , Mario Chavez

Epilepsy is a neurological disorder identified by sudden and recurrent seizures, which are believed to be accompanied by distinct changes in brain dynamics. Exploring the dynamic changes of brain network states during seizures can pave the…

Signal Processing · Electrical Eng. & Systems 2023-10-06 Atefeh Khoshkhahtinat , Hoda Mohammadzade

Objective: The aim of this study is to develop an efficient and reliable epileptic seizure prediction system using intracranial EEG (iEEG) data, especially for people with drug-resistant epilepsy. The prediction procedure should yield…

Neural and Evolutionary Computing · Computer Science 2019-04-09 Ramy Hussein , Mohamed Osama Ahmed , Rabab Ward , Z. Jane Wang , Levin Kuhlmann , Yi Guo

Recent studies have shown that seizures can spread and terminate across brain areas via a rich diversity of spatiotemporal patterns. In particular, while the location of the seizure onset area is usually in-variant across seizures in a same…

Neurons and Cognition · Quantitative Biology 2018-05-09 Timothée Proix , Viktor K. Jirsa , Fabrice Bartolomei , Maxime Guye , Wilson Truccolo

Epilepsy is the second most common brain disorder after migraine. Automatic detection of epileptic seizures can considerably improve the patients' quality of life. Current Electroencephalogram (EEG)-based seizure detection systems encounter…

Signal Processing · Electrical Eng. & Systems 2018-03-28 Ramy Hussein , Hamid Palangi , Rabab Ward , Z. Jane Wang

Epilepsy is a disorder characterised by spontaneous, recurrent seizures. Both local and network abnormalities have been associated with epilepsy, and the exact processes generating seizures are thought to be heterogeneous and…

Neurons and Cognition · Quantitative Biology 2019-01-07 Yujiang Wang , Gabrielle Marie Schroeder , Nishant Sinha , Peter Neal Taylor
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