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Identifying the seizure onset zone (SOZ) in patients with focal epilepsy is essential for surgical treatment and remains challenging due to its dependence on visual judgment by clinical experts. The development of machine learning can…
Parkinson's disease (PD) belongs to the class of neurodegenerative disorders that affect the central nervous system. It is usually defined as the gradual loss of dopaminergic neurons in the substantia nigra pars compacta, which causes both…
An epileptic seizure is a transient event of abnormal excessive neuronal discharge in the brain. This unwanted event can be obstructed by detection of electrical changes in the brain that happen before the seizure takes place. The automatic…
Detailed analysis of seizure semiology, the symptoms and signs which occur during a seizure, is critical for management of epilepsy patients. Inter-rater reliability using qualitative visual analysis is often poor for semiological features.…
We develop a Bayesian bivariate spatial model for multivariate regression analysis applicable to studies examining the influence of genetic variation on brain structure. Our model is motivated by an imaging genetics study of the Alzheimer's…
Brain connectomics is still largely dominated by pairwise-based models, such as graphs, which cannot represent circulatory or higher-order functional interactions. In this paper, we propose a multimodal framework based on Topological Signal…
Epilepsy is a common neurological disorder characterized by abrupt seizures. Although seizures may appear random, they are often preceded by early warning signs in neural signals, notably, critical slowing down, a phenomenon in which the…
Epilepsy is a dynamic and complex neurological disease affecting about 1% of the worldwide population, among which 30% of the patients are drug-resistant. Epilepsy is characterized by recurrent episodes of paroxysmal neural discharges (the…
Normative mapping is a framework used to map population-level features of health-related variables. It is widely used in neuroscience research, but the literature lacks established protocols in modalities that do not support healthy control…
A seizure's electrographic dynamics are characterised by its spatiotemporal evolution, also termed dynamical "pathway" and the time it takes to complete that pathway, which results in the seizure's duration. Both seizure pathways and…
Epileptic seizures are considered as abnormally hypersynchronous neuronal activities of the brain. Do hypersynchronous neuronal activities in a brain region lead to seizure or the hypersynchronous activities take place due to the…
Alterations to structural and functional brain networks have been reported across many neurological conditions. However, the relationship between structure and function -- their coupling -- is relatively unexplored, particularly in the…
Epilepsy is a neurological condition such that it affects the brain and the nervous system. It is characterized by recurrent seizures, which are physical reactions to sudden, usually brief, excessive electrical discharges in a group of…
Riemannian geometry has been applied to Brain Computer Interface (BCI) for brain signals classification yielding promising results. Studying electroencephalographic (EEG) signals from their associated covariance matrices allows a mitigation…
Seizure activity is a ubiquitous and pernicious pathophysiology that, in principle, should yield to mathematical treatments of (neuronal) ensemble dynamics - and therefore interventions on stochastic chaos. A seizure can be characterised as…
Identifying seizure activities in non-stationary electroencephalography (EEG) is a challenging task, since it is time-consuming, burdensome, and dependent on expensive human resources and subject to error and bias. A computerized seizure…
Seizure and synchronization are related to each other in complex manner. Altered synchrony has been implicated in loss of consciousness during partial seizures. However, the mechanism of altered consciousness following termination of…
Many coordination phenomena in Nature are grounded on a synchronisation regime. In the case of brain dynamics, such self-organised process allows the neurons of particular brain regions to behave as a whole and thus directly controlling the…
Schizophrenia (SZ) is a mental disorder whereby due to the secretion of specific chemicals in the brain, the function of some brain regions is out of balance, leading to the lack of coordination between thoughts, actions, and emotions. This…
A major challenge in cognitive neuroscience is to evaluate the ability of the human brain to categorize or group visual stimuli based on common features. This categorization process is very fast and occurs in few hundreds of millisecond…