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In the world, about 7 to 10 million elderly people are suffering from Parkinson's Disease (PD) disease. Parkinson's disease is a common neurological degenerative disease, and its clinical characteristics are Tremors, rigidity, bradykinesia,…
The ability to predict the future trajectory of a patient is a key step toward the development of therapeutics for complex diseases such as Alzheimer's disease (AD). However, most machine learning approaches developed for prediction of…
Vision-Language Pre-Trained models, notably CLIP, that utilize contrastive learning have proven highly adept at extracting generalizable visual features. To inherit the well-learned knowledge of VLP models for downstream tasks, several…
Alzheimer's disease is a progressive neurodegenerative disorder that remains challenging to predict due to its multifactorial etiology and the complexity of multimodal clinical data. Accurate forecasting of clinically relevant biomarkers,…
Pneumonia has been one of the fatal diseases and has the potential to result in severe consequences within a short period of time, due to the flow of fluid in lungs, which leads to drowning. If not acted upon by drugs at the right time,…
Diabetic retinopathy (DR) is the primary cause of vision loss among grownup people around the world. In four out of five cases having diabetes for a prolonged period leads to DR. If detected early, more than 90 percent of the new DR…
Medical image classification is one of the most important tasks for computer-aided diagnosis. Deep learning models, particularly convolutional neural networks, have been successfully used for disease classification from medical images,…
Recent studies on modelling the progression of Alzheimer's disease use a single modality for their predictions while ignoring the time dimension. However, the nature of patient data is heterogeneous and time dependent which requires models…
The development of statistical approaches for the joint modelling of the temporal changes of imaging, biochemical, and clinical biomarkers is of paramount importance for improving the understanding of neurodegenerative disorders, and for…
Early diagnosis of treatable diseases is essential for improving healthcare, and many diseases' onsets are predictable from annual lab tests and their temporal trends. We introduce a multi-resolution convolutional neural network for early…
Understanding the interactions between biomarkers among brain regions during neurodegenerative disease is essential for unravelling the mechanisms underlying disease progression. For example, pathophysiological models of Alzheimer's Disease…
Diabetic Retinopathy (DR) is a serious and common complication of diabetes, caused by prolonged high blood sugar levels that damage the small retinal blood vessels. If left untreated, DR can progress to retinal vein occlusion and stimulate…
Diabetic retinopathy (DR) is a growing health problem worldwide and is a leading cause of visual impairment and blindness, especially among working people aged 20-65. Its incidence is increasing along with the number of diabetes cases, and…
Idiopathic pulmonary fibrosis (IPF) is a progressive disease that irreversibly transforms lung tissue into rigid fibrotic structures, leading to debilitating symptoms such as shortness of breath and chronic fatigue. The heterogeneity and…
Background. Alzheimer's disease and related dementia (ADRD) are characterized by multiple and progressive anatomo clinical changes. Yet, modeling changes over disease course from cohort data is challenging as the usual timescales are…
Alzheimer's disease (AD) is a progressive and irreversible brain disorder that unfolds over the course of 30 years. Therefore, it is critical to capture the disease progression in an early stage such that intervention can be applied before…
Experts use retinal images and vessel trees to detect and diagnose various eye, blood circulation, and brain-related diseases. However, manual segmentation of retinal images is a time-consuming process that requires high expertise and is…
Here, we examine the latest advances in glaucoma detection through Deep Learning (DL) algorithms using Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). This study focuses on three aspects of DL-based glaucoma…
In this work, we introduce Brain Latent Progression (BrLP), a novel spatiotemporal disease progression model based on latent diffusion. BrLP is designed to predict the evolution of diseases at the individual level on 3D brain MRIs. Existing…
Modeling the time-series of high-dimensional, longitudinal data is important for predicting patient disease progression. However, existing neural network based approaches that learn representations of patient state, while very flexible, are…