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Large amounts of unlabelled data are commonplace for many applications in computational pathology, whereas labelled data is often expensive, both in time and cost, to acquire. We investigate the performance of unsupervised and supervised…

Computer Vision and Pattern Recognition · Computer Science 2019-07-27 Koen Dercksen , Wouter Bulten , Geert Litjens

Data is the engine of modern computer vision, which necessitates collecting large-scale datasets. This is expensive, and guaranteeing the quality of the labels is a major challenge. In this paper, we investigate efficient annotation…

Computer Vision and Pattern Recognition · Computer Science 2021-04-27 Yuan-Hong Liao , Amlan Kar , Sanja Fidler

Convolutional Neural Network (CNN)-based accurate prediction typically requires large-scale annotated training data. In Medical Imaging, however, both obtaining medical data and annotating them by expert physicians are challenging; to…

Computer Vision and Pattern Recognition · Computer Science 2019-05-30 Changhee Han , Kohei Murao , Shin'ichi Satoh , Hideki Nakayama

Definitive cancer diagnosis and management depend upon the extraction of information from microscopy images by pathologists. These images contain complex information requiring time-consuming expert human interpretation that is prone to…

In computational pathology, deep learning (DL) models for tasks such as segmentation or tissue classification are known to suffer from domain shifts due to different staining techniques. Stain adaptation aims to reduce the generalization…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Daniel Reisenbüchler , Lucas Luttner , Nadine S. Schaadt , Friedrich Feuerhake , Dorit Merhof

Large amounts of annotated data have become more important than ever, especially since the rise of deep learning techniques. However, manual annotations are costly. We propose a tool that enables researchers to create large, high-quality,…

Digital Libraries · Computer Science 2021-12-23 Franziska Weeber , Felix Hamborg , Karsten Donnay , Bela Gipp

Computational pathology, integrating computational methods and digital imaging, has shown to be effective in advancing disease diagnosis and prognosis. In recent years, the development of machine learning and deep learning has greatly…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Jiamu Wang , Chang-Su Kim , Jin Tae Kwak

It is increasingly common clinically for cancer specimens to be examined using techniques that identify somatic mutations. In principle these mutational profiles can be used to diagnose the tissue of origin, a critical task for the 3-5% of…

Methodology · Statistics 2020-07-14 Saptarshi Chakraborty , Colin B. Begg , Ronglai Shen

Although machine learning has become a powerful tool to augment doctors in clinical analysis, the immense amount of labeled data that is necessary to train supervised learning approaches burdens each development task as time and resource…

Often in medical imaging, it is prohibitively challenging to produce enough boundary annotations to train deep neural networks for accurate tumor segmentation. We propose the use of weak labels about whether an image presents tumor or…

Computer Vision and Pattern Recognition · Computer Science 2021-06-15 Eugene Vorontsov , Pavlo Molchanov , Christopher Beckham , Jan Kautz , Samuel Kadoury

Accurate Computer-Assisted Diagnosis, associated with proper data wrangling, can alleviate the risk of overlooking the diagnosis in a clinical environment. Towards this, as a Data Augmentation (DA) technique, Generative Adversarial Networks…

Computer Vision and Pattern Recognition · Computer Science 2019-08-23 Changhee Han , Kohei Murao , Tomoyuki Noguchi , Yusuke Kawata , Fumiya Uchiyama , Leonardo Rundo , Hideki Nakayama , Shin'ichi Satoh

Understanding the progression of cancer is crucial for defining treatments for patients. The objective of this study is to automate the detection of metastatic liver disease from free-style computed tomography (CT) radiology reports. Our…

Machine Learning · Computer Science 2023-10-31 Maede Ashofteh Barabadi , Xiaodan Zhu , Wai Yip Chan , Amber L. Simpson , Richard K. G. Do

Scalable and accurate identification of specific clinical outcomes has been enabled by machine-learning applied to electronic medical record (EMR) systems. The development of classification models requires the collection of a complete…

Methodology · Statistics 2020-11-09 W. Katherine Tan , Patrick J. Heagerty

Unstructured notes within the electronic health record (EHR) contain rich clinical information vital for cancer treatment decision making and research, yet reliably extracting structured oncology data remains challenging due to extensive…

Accurate gross tumor volume segmentation on multi-modal medical data is critical for radiotherapy planning in nasopharyngeal carcinoma and glioblastoma. Recent advances in deep neural networks have brought promising results in medical image…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Jingyun Yang , Guoqing Zhang , Jingge Wang , Yang Li

Objective: This review aims to analyze the application of natural language processing (NLP) techniques in cancer research using electronic health records (EHRs) and clinical notes. This review addresses gaps in the existing literature by…

Computation and Language · Computer Science 2025-02-05 Muhammad Bilal , Ameer Hamza , Nadia Malik

Recent rapid increase in the generation of clinical data and rapid development of computational science make us able to extract new insights from massive datasets in healthcare industry. Oncological clinical notes are creating rich…

Artificial Intelligence · Computer Science 2018-09-24 Marjan Najafabadipour , Juan Manuel Tuñas , Alejandro Rodríguez-González , Ernestina Menasalvas

Classification models that provide human-interpretable explanations enhance clinicians' trust and usability in medical image diagnosis. One research focus is the integration and prediction of pathology-related visual attributes used by…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Luisa Gallée , Catharina Silvia Lisson , Christoph Gerhard Lisson , Daniela Drees , Felix Weig , Daniel Vogele , Meinrad Beer , Michael Götz

Purpose: An investigation of the challenge of annotating discrete segmentations of brain tumours in ultrasound, with a focus on the issue of aleatoric uncertainty along the tumour margin, particularly for diffuse tumours. A segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Alistair Weld , Luke Dixon , Alfie Roddan , Giulio Anichini , Sophie Camp , Stamatia Giannarou

To efficiently establish training databases for machine learning methods, collaborative and crowdsourcing platforms have been investigated to collectively tackle the annotation effort. However, when this concept is ported to the medical…

Computer Vision and Pattern Recognition · Computer Science 2017-08-22 Martin Rajchl , Lisa M. Koch , Christian Ledig , Jonathan Passerat-Palmbach , Kazunari Misawa , Kensaku Mori , Daniel Rueckert