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Relation extraction (RE) plays an important role in extracting knowledge from unstructured text but requires a large amount of labeled corpus. To reduce the expensive annotation efforts, semisupervised learning aims to leverage both labeled…

Computation and Language · Computer Science 2021-03-16 Yusen Lin

Unlike traditional fact-based retrieval, rationale-based retrieval typically necessitates cross-encoding of query-document pairs using large language models, incurring substantial computational costs. To address this limitation, we propose…

Information Retrieval · Computer Science 2026-05-14 Teng Chen , Sheng Xu , Feixiang Guo , Xiaoyu Wang , Qingqing Gu , Hongyan Li , Luo Ji

Self-supervised learning has been a powerful approach for learning meaningful representations from unlabeled data across various domains, reducing the reliance on large labeled datasets. Inspired by BERT's success in capturing deep…

Machine Learning · Computer Science 2025-02-05 Hoang M. Nguyen , Satya N. Shukla , Qiang Zhang , Hanchao Yu , Sreya D. Roy , Taipeng Tian , Lingjiong Zhu , Yuchen Liu

Analysis of single-cell transcriptomics often relies on clustering cells and then performing differential gene expression (DGE) to identify genes that vary between these clusters. These discrete analyses successfully determine cell types…

Quantitative Methods · Quantitative Biology 2022-10-07 Renee S. Hoekzema , Lewis Marsh , Otto Sumray , Thomas M. Carroll , Xin Lu , Helen M. Byrne , Heather A. Harrington

Genome annotation is an important issue in biology which has long been addressed with gene prediction methods and manual experiments requiring biological expertise. The expanding Next Generation Sequencing technologies and their enhanced…

Computation · Statistics 2013-07-02 Alice Cleynen , Michel Koskas , Emilie Lebarbier , Guillem Rigaill , Stephane Robin

Reinforcement learning (RL) has garnered increasing recognition for its potential to optimise dynamic treatment regimes (DTRs) in personalised medicine, particularly for drug dosage prescriptions and medication recommendations. However, a…

Machine Learning · Computer Science 2024-05-30 Zhiyao Luo , Mingcheng Zhu , Fenglin Liu , Jiali Li , Yangchen Pan , Jiandong Zhou , Tingting Zhu

Background: With the rapid growth of massively parallel sequencing technologies, still more laboratories are utilizing sequenced DNA fragments for genomic analyses. Interpretation of sequencing data is, however, strongly dependent on…

Retrieval-Augmented Generation (RAG) delivers substantial value in knowledge-intensive applications. However, its generated responses often lack transparent reasoning paths that trace back to source evidence from retrieved documents. This…

Computation and Language · Computer Science 2026-01-30 Jingyi Ren , Yekun Xu , Xiaolong Wang , Weitao Li , Ante Wang , Weizhi Ma , Yang Liu

The standard methods for detecting differential gene expression are mostly designed for analyzing a single gene expression experiment. When data from multiple related gene expression studies are available, separately analyzing each study is…

Methodology · Statistics 2013-11-07 Yingying Wei , Hongkai Ji

Bootstrapping is a popular and computationally demanding resampling method used for measuring the accuracy of sample estimates and assisting with statistical inference. R is a freely available language and environment for statistical…

Computation · Statistics 2014-01-27 T. M. Sloan , M. Piotrowski , T. Forster , P. Ghazal

In the domain of semi-supervised learning (SSL), the conventional approach involves training a learner with a limited amount of labeled data alongside a substantial volume of unlabeled data, both drawn from the same underlying distribution.…

Machine Learning · Computer Science 2023-08-29 Guy Hacohen , Daphna Weinshall

Text Classification is one of the fundamental tasks in natural language processing, which requires an agent to determine the most appropriate category for input sentences. Recently, deep neural networks have achieved impressive performance…

Computation and Language · Computer Science 2023-06-16 Kun Zhang , Le Wu , Guangyi Lv , Enhong Chen , Shulan Ruan , Jing Liu , Zhiqiang Zhang , Jun Zhou , Meng Wang

Retrieval-augmented Generation (RAG) has demonstrated potential in enhancing medical question-answering systems through the integration of large language models (LLMs) with external medical literature. LLMs can retrieve relevant medical…

Computation and Language · Computer Science 2025-10-29 Mengzhou Sun , Sendong Zhao , Jianyu Chen , Haochun Wang , Bin Qin

Diffusion large language models (dLLMs) are emerging as a compelling alternative to dominant autoregressive models, replacing strictly sequential token generation with iterative denoising and parallel generation dynamics. However, their…

Computation and Language · Computer Science 2026-04-07 Jingyi Yang , Yuxian Jiang , Xuhao Hu , Shuang Cheng , Biqing Qi , Jing Shao

Automated deidentification of clinical text data is crucial due to the high cost of manual deidentification, which has been a barrier to sharing clinical text and the advancement of clinical natural language processing. However, creating…

Computation and Language · Computer Science 2023-11-07 Callandra Moore , Jonathan Ranisau , Walter Nelson , Jeremy Petch , Alistair Johnson

In this paper, we present a new approach to improving the relevance and reliability of medical IR, which builds upon the concept of Level of Evidence (LoE). LoE framework categorizes medical publications into 7 distinct levels based on the…

Information Retrieval · Computer Science 2025-05-20 Sameh Frihat , Norbert Fuhr

Large reasoning models (LRMs) have shown significant progress in test-time scaling through chain-of-thought prompting. Current approaches like search-o1 integrate retrieval augmented generation (RAG) into multi-step reasoning processes but…

Computation and Language · Computer Science 2026-01-21 Kaiwen Wei , Rui Shan , Dongsheng Zou , Jianzhong Yang , Bi Zhao , Junnan Zhu , Jiang Zhong

Evaluating the quality and variability of text generated by Large Language Models (LLMs) poses a significant, yet unresolved research challenge. Traditional evaluation methods, such as ROUGE and BERTScore, which measure token similarity,…

Computation and Language · Computer Science 2024-01-05 Wendi Cui , Jiaxin Zhang , Zhuohang Li , Lopez Damien , Kamalika Das , Bradley Malin , Sricharan Kumar

Document-level relation extraction has attracted much attention in recent years. It is usually formulated as a classification problem that predicts relations for all entity pairs in the document. However, previous works indiscriminately…

Computation and Language · Computer Science 2021-06-04 Shuang Zeng , Yuting Wu , Baobao Chang

Relevance judgments are crucial for evaluating information retrieval systems, but traditional human-annotated labels are time-consuming and expensive. As a result, many researchers turn to automatic alternatives to accelerate method…

Information Retrieval · Computer Science 2025-07-15 Naghmeh Farzi , Laura Dietz