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Multispectral photoacoustic tomography (PAT) is an imaging modality that utilizes the photoacoustic effect to achieve non-invasive and high-contrast imaging of internal tissues. However, the hardware cost and computational demand of a…

Image and Video Processing · Electrical Eng. & Systems 2024-04-11 Yutian Zhong , Xiaoming Zhang , Zongxin Mo , Shuangyang Zhang , Wufan Chen , Li Qi

Fabry-P\'erot based photoacoustic tomography (FP-PAT) is a promising all-optical imaging modality for a wide range of preclinical and clinical applications. However, there exist several challenges in routinely applying FP-PAT in…

Optics · Physics 2025-12-01 Jakub Czuchnowski , Robert Prevedel

In optoacoustic (photoacoustic) tomography, several parameters related to tissue and detector features are needed for image formation, but they may not be known a priori. An autofocus (AF) algorithm is generally used to estimate these…

Medical Physics · Physics 2022-03-14 Ludwig Englert , Lucas Riobo , Christine Schonemann , Vasilis Ntziachristos , Juan Aguirre

Imaging technologies have been developed to assist physicians and dentist in the detection of various diseases. Photoacoustic imaging (PAI) is a new imaging technique that shows great promise to image soft tissues. The prototype of PAI…

Medical Physics · Physics 2017-12-11 Rini Widyaningrum , Rellyca Sola Gracea , Dewi Agustina , Munakhir Mudjosemedi , Mitrayana

Simulated annealing tomography (SAT) is a simple iterative image reconstruction technique which can yield a superior reconstruction compared with filtered back-projection (FBP). However, the very high computational cost of iteratively…

Computational Physics · Physics 2014-11-18 Nghia T. Vo , Mark B. H. Breese , Herbert O. Moser

Non-invasive imaging of deep blood vessels for mapping hemodynamics remains an open quest in biomedical optical imaging. Although pure optical imaging techniques offer rich optical contrast of blood and have been reported to measure blood…

Medical Physics · Physics 2022-09-20 Yang Zhang , Joshua Olick-Gibson , Anjul Khadria , Lihong V. Wang

Photoacoustic tomography leverages ultrasound's deep tissue penetration to retrieve optical absorption contrast well beyond the optical diffusion limit. Conventional photoacoustic systems rely on externally delivered light and are therefore…

Optics · Physics 2026-01-06 David C. Garrett , Lihong V. Wang

Iterative model-based image reconstruction in photoacoustic tomography (PAT) enables principled incorporation of detector physics, object-related priors, and complex acquisition strategies. However, for three-dimensional (3D) imaging…

Localization-based imaging has revolutionized fluorescence optical microscopy and has also enabled unprecedented ultrasound images of microvascular structures in deep tissues. Herein, we introduce a new concept of localization optoacoustic…

Optics · Physics 2017-07-10 Xose Luis Dean-Ben , Daniel Razansky

Binaural Audio Telepresence (BAT) aims to encode the acoustic scene at the far end into binaural signals for the user at the near end. BAT encompasses an immense range of applications that can vary between two extreme modes of Immersive BAT…

Audio and Speech Processing · Electrical Eng. & Systems 2024-05-15 Yicheng Hsu , Mingsian R. Bai

As a hybrid imaging technology, photoacoustic microscopy (PAM) imaging suffers from noise due to the maximum permissible exposure of laser intensity, attenuation of ultrasound in the tissue, and the inherent noise of the transducer.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Da He , Jiasheng Zhou , Xiaoyu Shang , Jiajia Luo , Sung-Liang Chen

Accurate image reconstruction is crucial for photoacoustic (PA) computed tomography (PACT). Recently, deep learning has been used to reconstruct the PA image with a supervised scheme, which requires high-quality images as ground truth…

Image and Video Processing · Electrical Eng. & Systems 2023-09-22 Hengrong Lan , Lijie Huang , Zhiqiang Li , Jing Lv , Jianwen Luo

Photoacoustic tomography seeks to reconstruct an acoustic initial pressure distribution from the measurement of the ultrasound waveforms. Conventional methods assume a-prior knowledge of the sound speed distribution, which practically is…

Image and Video Processing · Electrical Eng. & Systems 2019-09-16 Hongming Shan , Christopher Wiedeman , Ge Wang , Yang Yang

Delay alignment modulation (DAM) is a novel transmission technique for wireless systems with high spatial resolution by leveraging delay compensation and path-based beamforming, to mitigate the inter-symbol interference (ISI) without…

Signal Processing · Electrical Eng. & Systems 2024-07-31 Zhiwen Zhou , Zhiqiang Xiao , Yong Zeng

Accurate measurement of optical absorption coefficients from photoacoustic imaging (PAI) data would enable direct mapping of molecular concentrations, providing vital clinical insight. The ill-posed nature of the problem of absorption…

Image and Video Processing · Electrical Eng. & Systems 2023-06-13 Janek Gröhl , Thomas R. Else , Lina Hacker , Ellie V. Bunce , Paul W. Sweeney , Sarah E. Bohndiek

We developed an optical-resolution photoacoustic microscope (OR-PAM) capable of changing focal plane with high-speed by using a tunable acoustic gradient (TAG) lens. In our system, a TAG lens is designed to continuously changing the focal…

Optics · Physics 2020-09-09 Xianlin Song

Photoacoustic imaging is an emerging technology based on the photoacoustic effect that has developed rapidly in recent years. It combines the high contrast of optical imaging and the high penetration and high resolution of acoustic imaging.…

Spherical matrix arrays arguably represent an advantageous tomographic detection geometry for non-invasive deep tissue mapping of vascular networks and oxygenation with volumetric optoacoustic tomography (VOT). Hybridization of VOT with…

Medical Physics · Physics 2021-01-05 Justine Robin , Ali Ozbek , Michael Reiss , Xose-Luis Dean-Ben , Daniel Razansky

Deep learning (DL)-based image reconstruction methods for photoacoustic computed tomography (PACT) have developed rapidly in recent years. However, most existing methods have not employed standardized datasets, and their evaluations rely on…

Medical Physics · Physics 2026-01-27 Panpan Chen , Seonyeong Park , Gangwon Jeong , Refik Mert Cam , Umberto Villa , Mark A. Anastasio

Photoacoustic microscopy (PAM) is a promising imaging modality because it is able to reveal optical absorption contrast in high resolution on the order of a micrometer. It can be applied in an endoscopic approach by implementing PAM into a…

Medical Physics · Physics 2019-11-22 Zhendong Guo , Zhanhong Ye , Weihao Shao , Lili Jing , Sung-Liang Chen
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