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The outbreak of Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic affecting over 200 countries and regions. Inference about the transmission dynamics of COVID-19 can provide important insights into the speed of disease spread and…

Methodology · Statistics 2020-07-06 Tianjian Zhou , Yuan Ji

This work constructs, analyzes, and simulates a new compartmental SEIR-type model for the dynamics and potential control of the current COVID-19 pandemic. The novelty in this work is two-fold. First, the population is divided according to…

Populations and Evolution · Quantitative Biology 2021-05-14 Aycil Cesmelioglu , Kenneth L. Kuttler , Meir Shillor , Anna M. Spagnuolo

The present article studies the extension of two deterministic models for describing the novel coronavirus pandemic crisis, the SIR model and the SEIR model. The models were studied and compared to real data in order to support the validity…

Physics and Society · Physics 2020-06-05 P. H. P. Cintra , M. F. Citeli , F. N. Fontinele

We study the problem of optimal control of the stochastic SIR model. Models of this type are used in mathematical epidemiology to capture the time evolution of highly infectious diseases such as COVID-19. Our approach relies on…

Populations and Evolution · Quantitative Biology 2020-05-04 Andrew Lesniewski

The COVID-19 pandemic has highlighted the need for quantitative modeling and analysis to understand real-world disease dynamics. In particular, post hoc analyses using compartmental models offer valuable insights into the effectiveness of…

Machine Learning · Computer Science 2025-10-09 Phillip Rothenbeck , Sai Karthikeya Vemuri , Niklas Penzel , Joachim Denzler

We demonstrate the ability of statistical data assimilation to identify the measurements required for accurate state and parameter estimation in an epidemiological model for the novel coronavirus disease COVID-19. Our context is an effort…

Populations and Evolution · Quantitative Biology 2020-08-04 Eve Armstrong , Manuela Runge , Jaline Gerardin

The infection dynamics of a population under stationary isolation conditions is modeled. It is underlined that the stationary character of the isolation measures can be expected to imply that an effective SIR model with constant parameters…

Populations and Evolution · Quantitative Biology 2021-10-19 Alejandro Cabo Montes de Oca , Nana Geraldine Cabo Bizet

As global living standards improve and medical technology advances, many infectious diseases have been effectively controlled. However, certain diseases, such as the recent COVID-19 pandemic, continue to pose significant threats to public…

Numerical Analysis · Mathematics 2025-02-24 Ayesha Baig , Li Zhouxin

The mobility patterns of individuals in China during the early outbreak of the COVID-19 pandemic exhibit reversible changes -- in many regions, the mobility first decreased significantly and later restored. Based on this observation, here…

Physics and Society · Physics 2022-10-25 Xincheng Shu , Zhongyuan Ruan

Measures to reduce the impact of the COVID-19 pandemic require a mix of logistic, political and social capacity. Depending on the country, different approaches to increase hospitalization capacity or to properly apply lock-downs are…

Populations and Evolution · Quantitative Biology 2020-06-12 Tomas Veloz , Pedro Maldonado , Samuel Ropert , Cesar Ravello , Soraya Mora , Alejandra Barrios , Tomas Villaseca , Cesar Valdenegro , Tomas Perez-Acle

Epidemics like Covid-19 and Ebola have impacted people's lives significantly. The impact of mobility of people across the countries or states in the spread of epidemics has been significant. The spread of disease due to factors local to the…

Populations and Evolution · Quantitative Biology 2022-05-04 Nirmal Kumar Sivaraman , Manas Gaur , Shivansh Baijal , Sakthi Balan Muthiah , Amit Sheth

A study of changes in the transmission of a disease, in particular, a new disease like COVID-19, requires very flexible models which can capture, among others, the effects of non-pharmacological and pharmacological measures, changes in…

At the time of writing, the ongoing COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), had already resulted in more than thirty-two million cases infected and more than one million deaths worldwide.…

Optimization and Control · Mathematics 2023-03-22 Chung-Han Hsieh

The COVID-19 pandemic has emphasized the need for a robust understanding of epidemic models. Current models of epidemics are classified as either mechanistic or non-mechanistic: mechanistic models make explicit assumptions on the dynamics…

Machine Learning · Statistics 2022-01-14 Arnab Sarker , Ali Jadbabaie , Devavrat Shah

Susceptible-Invective-Recovered (SIR) mathematical models are in high demand due to the COVID-19 pandemic. They are used in their standard formulation, or through the many variants, trying to fit and hopefully predict the number of new…

Populations and Evolution · Quantitative Biology 2020-05-19 Ben-Hur Francisco Cardoso , Sebastián Gonçalves

In the new paradigm of health-centric governance, policy makers are in a constant need for appropriate metrics and estimates in order to determine the best policies in a non-arbitrary fashion. Thus, in this paper, a compartmentalized model…

Populations and Evolution · Quantitative Biology 2022-04-20 Suryadeepto Nag , Siddhartha P. Chakrabarty

The constrained outbreak of COVID-19 in Mainland China has recently been regarded as a successful example of fighting this highly contagious virus. Both the short period (in about three months) of transmission and the sub-exponential…

Physics and Society · Physics 2022-03-22 Jizhou Huang , Haifeng Wang , Miao Fan , An Zhuo , Yibo Sun , Ying Li

We present a new mathematical model to explicitly capture the effects that the three restriction measures: the lockdown date and duration, social distancing and masks, and, schools and border closing, have in controlling the spread of…

Populations and Evolution · Quantitative Biology 2020-08-25 Liam Dowling Jones , Malik Magdon-Ismail , Laura Mersini-Houghton , Steven Meshnick

Calibration of a SIR (Susceptibles-Infected-Recovered) model with official international data for the COVID-19 pandemics provides a good example of the difficulties inherent the solution of inverse problems. Inverse modeling is set up in a…

Populations and Evolution · Quantitative Biology 2020-06-09 Mauro Giudici , Alessandro Comunian , Romina Gaburro

We propose a general Bayesian approach to modeling epidemics such as COVID-19. The approach grew out of specific analyses conducted during the pandemic, in particular an analysis concerning the effects of non-pharmaceutical interventions…

Applications · Statistics 2021-01-01 Samir Bhatt , Neil Ferguson , Seth Flaxman , Axel Gandy , Swapnil Mishra , James A. Scott