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Evaluation of artificial intelligence (AI) models for low-dose CT lung cancer screening is limited by heterogeneous datasets, annotation standards, and evaluation protocols, making performance difficult to compare and translate across…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Fakrul Islam Tushar , Avivah Wang , Lavsen Dahal , Ehsan Samei , Michael R. Harowicz , Jayashree Kalpathy-Cramer , Kyle J. Lafata , Tina D. Tailor , Cynthia Rudin , Joseph Y. Lo

Accurate delineation of anatomical structures in volumetric CT scans is crucial for diagnosis and treatment planning. While AI has advanced automated segmentation, current approaches typically target individual structures, creating a…

Medical imaging is an essential tool in many areas of medical applications, used for both diagnosis and treatment. However, reading medical images and making diagnosis or treatment recommendations require specially trained medical…

Computer Vision and Pattern Recognition · Computer Science 2019-03-13 Wentao Zhu

Lung segmentation in computerized tomography (CT) images is an important procedure in various lung disease diagnosis. Most of the current lung segmentation approaches are performed through a series of procedures with manually empirical…

Computer Vision and Pattern Recognition · Computer Science 2019-01-14 Jiaxing Tan , Longlong Jing , Yumei Huo , Yingli Tian , Oguz Akin

BACKGROUND AND OBJECTIVES: The multiple chest x-ray datasets released in the last years have ground-truth labels intended for different computer vision tasks, suggesting that performance in automated chest-xray interpretation might improve…

Weakly supervised disease classification of CT imaging suffers from poor localization owing to case-level annotations, where even a positive scan can hold hundreds to thousands of negative slices along multiple planes. Furthermore, although…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Anindo Saha , Fakrul I. Tushar , Khrystyna Faryna , Vincent M. D'Anniballe , Rui Hou , Maciej A. Mazurowski , Geoffrey D. Rubin , Joseph Y. Lo

Purpose: To develop a radiomics filtering technique for characterizing spatial-encoded regional pulmonary ventilation information on lung CT. Methods: The lung volume was segmented on 46 CT images, and a 3D sliding window kernel was…

Medical Physics · Physics 2023-01-11 Zhenyu Yang , Kyle J Lafata , Xinru Chen , James Bowsher , Yushi Chang , Chunhao Wang , Fang-Fang Yin

Morphological analysis and identification of pathologies in the aorta are important for cardiovascular diagnosis and risk assessment in patients. Manual annotation is time-consuming and cumbersome in CT scans acquired without contrast…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Julia M. H. Noothout , Bob D. de Vos , Jelmer M. Wolterink , Ivana Isgum

Lung cancer has been one of the major threats to human life for decades. Computer-aided diagnosis can help with early lung nodul detection and facilitate subsequent nodule characterization. Large Visual Language models (VLMs) have been…

Image and Video Processing · Electrical Eng. & Systems 2024-07-04 Furqan Shaukat , Syed Muhammad Anwar , Abhijeet Parida , Van Khanh Lam , Marius George Linguraru , Mubarak Shah

Breast cancer screening is one of the most common radiological tasks with over 39 million exams performed each year. While breast cancer screening has been one of the most studied medical imaging applications of artificial intelligence, the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-22 Mateusz Buda , Ashirbani Saha , Ruth Walsh , Sujata Ghate , Nianyi Li , Albert Święcicki , Joseph Y. Lo , Maciej A. Mazurowski

The cells and their spatial patterns in the tumor microenvironment (TME) play a key role in tumor evolution, and yet the latter remains an understudied topic in computational pathology. This study, to the best of our knowledge, is among the…

Quantitative Methods · Quantitative Biology 2021-09-21 Pingjun Chen , Muhammad Aminu , Siba El Hussein , Joseph D. Khoury , Jia Wu

Purpose To develop and demonstrate a novel tumor shell feature for predicting distant failure in non-small cell lung cancer (NSCLC) and cervical cancer (CC) patients. Patients and Methods The shell predictive model was constructed using…

We suggest that deep learning can be used for pre-screening cancer by analyzing demographic and anthropometric information of patients, as well as biological markers obtained from routine blood samples and relative risks obtained from…

Machine Learning · Statistics 2023-02-07 Rolando Gonzales Martinez , Daan-Max van Dongen

We introduce the largest abdominal CT dataset (termed AbdomenAtlas) of 20,460 three-dimensional CT volumes sourced from 112 hospitals across diverse populations, geographies, and facilities. AbdomenAtlas provides 673K high-quality masks of…

Gastric cancer is the third leading cause of cancer-related mortality worldwide, but no guideline-recommended screening test exists. Existing methods can be invasive, expensive, and lack sensitivity to identify early-stage gastric cancer.…

Image and Video Processing · Electrical Eng. & Systems 2023-07-18 Mingze Yuan , Yingda Xia , Xin Chen , Jiawen Yao , Junli Wang , Mingyan Qiu , Hexin Dong , Jingren Zhou , Bin Dong , Le Lu , Li Zhang , Zaiyi Liu , Ling Zhang

Low-dose chest computed tomography (LDCT) captures pulmonary and cardiac structures in a single scan, enabling joint assessment of lung and cardiovascular health. Existing approaches typically model these domains independently and do not…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Yifei Zhang , Jiashuo Zhang , Mojtaba Safari , Xiaofeng Yang , Liang Zhao

Chest radiographs are primarily employed for the screening of pulmonary and cardio-/thoracic conditions. Being undertaken at primary healthcare centers, they require the presence of an on-premise reporting Radiologist, which is a challenge…

Computer Vision and Pattern Recognition · Computer Science 2020-04-27 Arka Mitra , Arunava Chakravarty , Nirmalya Ghosh , Tandra Sarkar , Ramanathan Sethuraman , Debdoot Sheet

Machine learning models for radiology benefit from large-scale data sets with high quality labels for abnormalities. We curated and analyzed a chest computed tomography (CT) data set of 36,316 volumes from 19,993 unique patients. This is…

Image and Video Processing · Electrical Eng. & Systems 2020-10-14 Rachel Lea Draelos , David Dov , Maciej A. Mazurowski , Joseph Y. Lo , Ricardo Henao , Geoffrey D. Rubin , Lawrence Carin

Lung cancer continues to be the predominant cause of cancer-related mortality globally. This review analyzes various approaches, including advanced image processing methods, focusing on their efficacy in interpreting CT scans, chest…

Reconstruction kernels in computed tomography (CT) affect spatial resolution and noise characteristics, introducing systematic variability in quantitative imaging measurements such as emphysema quantification. Choosing an appropriate kernel…

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