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Pretraining DNA language models (DNALMs) on the full human genome is resource-intensive, yet often considered necessary for strong downstream performance. Inspired by recent findings in NLP and long-context modeling, we explore an…

Genomics · Quantitative Biology 2025-06-24 Sohan Mupparapu , Parameswari Krishnamurthy , Ratish Puduppully

Recent advancements in immune sequencing and experimental techniques are generating extensive T cell receptor (TCR) repertoire data, enabling the development of models to predict TCR binding specificity. Despite the computational challenges…

Quantitative Methods · Quantitative Biology 2024-07-24 Anna Weber , Aurélien Pélissier , María Rodríguez Martínez

Language model based pre-trained models such as BERT have provided significant gains across different NLP tasks. In this paper, we study different types of transformer based pre-trained models such as auto-regressive models (GPT-2),…

Computation and Language · Computer Science 2021-02-02 Varun Kumar , Ashutosh Choudhary , Eunah Cho

Pre-trained vision-language models learn massive data to model unified representations of images and natural languages, which can be widely applied to downstream machine learning tasks. In addition to zero-shot inference, in order to better…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Qian-Wei Wang , Yuqiu Xie , Letian Zhang , Zimo Liu , Shu-Tao Xia

Modern large-scale Pre-trained Language Models (PLMs) have achieved tremendous success on a wide range of downstream tasks. However, most of the LM pre-training objectives only focus on text reconstruction, but have not sought to learn…

Computation and Language · Computer Science 2022-10-28 Liliang Ren , Zixuan Zhang , Han Wang , Clare R. Voss , Chengxiang Zhai , Heng Ji

Training models on low-resource named entity recognition tasks has been shown to be a challenge, especially in industrial applications where deploying updated models is a continuous effort and crucial for business operations. In such cases…

Computation and Language · Computer Science 2019-10-18 Peter Izsak , Shira Guskin , Moshe Wasserblat

The 21st century is presenting humankind with unprecedented environmental and medical challenges. The ability to design novel proteins tailored for specific purposes could transform our ability to respond timely to these issues. Recent…

Biomolecules · Quantitative Biology 2022-08-24 Noelia Ferruz , Birte Höcker

Pre-trained language models (PLMs) aim to learn universal language representations by conducting self-supervised training tasks on large-scale corpora. Since PLMs capture word semantics in different contexts, the quality of word…

Computation and Language · Computer Science 2022-03-22 Wenhao Yu , Chenguang Zhu , Yuwei Fang , Donghan Yu , Shuohang Wang , Yichong Xu , Michael Zeng , Meng Jiang

Protein language models (pLMs) pre-trained on vast protein sequence databases excel at various downstream tasks but often lack the structural knowledge essential for some biological applications. To address this, we introduce a method to…

In this work, we are dedicated to leveraging the BERT pre-training success and modeling the domain-specific statistics to fertilize the sign language recognition~(SLR) model. Considering the dominance of hand and body in sign language…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Weichao Zhao , Hezhen Hu , Wengang Zhou , Jiaxin Shi , Houqiang Li

Fine-tuning Large Language Models (LLMs) is now a common approach for text classification in a wide range of applications. When labeled documents are scarce, active learning helps save annotation efforts but requires retraining of massive…

Machine Learning · Computer Science 2024-02-27 Artem Vysogorets , Achintya Gopal

Deep learning methods have advanced quickly in brain imaging analysis over the past few years, but they are usually restricted by the limited labeled data. Pre-trained model on unlabeled data has presented promising improvement in feature…

Neurons and Cognition · Quantitative Biology 2024-08-22 Jinlong Hu , Yangmin Huang , Nan Wang , Shoubin Dong

The massive scale and growth of textual biomedical data have made its indexing and classification increasingly important. However, existing research on this topic mainly utilized convolutional and recurrent neural networks, which generally…

Computation and Language · Computer Science 2022-03-08 Bruce Nguyen , Shaoxiong Ji

Sequence labeling is an important technique employed for many Natural Language Processing (NLP) tasks, such as Named Entity Recognition (NER), slot tagging for dialog systems and semantic parsing. Large-scale pre-trained language models…

Computation and Language · Computer Science 2020-12-14 Yaqing Wang , Subhabrata Mukherjee , Haoda Chu , Yuancheng Tu , Ming Wu , Jing Gao , Ahmed Hassan Awadallah

Recent developments in Natural Language Processing (NLP) demonstrate that large-scale, self-supervised pre-training can be extremely beneficial for downstream tasks. These ideas have been adapted to other domains, including the analysis of…

Computation and Language · Computer Science 2021-02-02 Matthew B. A. McDermott , Brendan Yap , Harry Hsu , Di Jin , Peter Szolovits

Pre-trained Language Model (PLM) has become a representative foundation model in the natural language processing field. Most PLMs are trained with linguistic-agnostic pre-training tasks on the surface form of the text, such as the masked…

Computation and Language · Computer Science 2022-11-11 Yiming Cui , Wanxiang Che , Shijin Wang , Ting Liu

The practice of fine-tuning Pre-trained Language Models (PLMs) from general or domain-specific data to a specific task with limited resources, has gained popularity within the field of natural language processing (NLP). In this work, we…

Computation and Language · Computer Science 2023-10-31 Samuel Belkadi , Lifeng Han , Yuping Wu , Goran Nenadic

This paper addresses the classification of Arabic text data in the field of Natural Language Processing (NLP), with a particular focus on Natural Language Inference (NLI) and Contradiction Detection (CD). Arabic is considered a…

Computation and Language · Computer Science 2023-07-28 Mohammad Majd Saad Al Deen , Maren Pielka , Jörn Hees , Bouthaina Soulef Abdou , Rafet Sifa

Pre-trained Language Models (PLMs) have been widely used in various natural language processing (NLP) tasks, owing to their powerful text representations trained on large-scale corpora. In this paper, we propose a new PLM called PERT for…

Computation and Language · Computer Science 2022-03-15 Yiming Cui , Ziqing Yang , Ting Liu

We introduce an extensive dataset for multilingual probing of morphological information in language models (247 tasks across 42 languages from 10 families), each consisting of a sentence with a target word and a morphological tag as the…

Computation and Language · Computer Science 2024-11-20 Judit Acs , Endre Hamerlik , Roy Schwartz , Noah A. Smith , Andras Kornai