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Despite fluorescent cell-labelling being widely employed in biomedical studies, some of its drawbacks are inevitable, with unsuitable fluorescent probes or probes inducing a functional change being the main limitations. Consequently, the…

Quantitative Methods · Quantitative Biology 2020-03-03 Yan Ge , Philipp Rosendahl , Claudio Durán , Nicole Töpfner , Sara Ciucci , Jochen Guck , Carlo Vittorio Cannistraci

Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Aniket Joshi , Gaurav Mishra , Jayanthi Sivaswamy

In many real-world pattern recognition scenarios, such as in medical applications, the corresponding classification tasks can be of an imbalanced nature. In the current study, we focus on binary, imbalanced classification tasks, i.e.~binary…

Machine Learning · Computer Science 2020-12-01 Peter Bellmann , Heinke Hihn , Daniel A. Braun , Friedhelm Schwenker

Class imbalance problem is commonly faced while developing machine learning models for real-life issues. Due to this problem, the fitted model tends to be biased towards the majority class data, which leads to lower precision, recall, AUC,…

Machine Learning · Computer Science 2019-08-20 Md. Adnan Arefeen , Sumaiya Tabassum Nimi , M Sohel Rahman

Prior work has shown that Visual Recognition datasets frequently underrepresent bias groups $B$ (\eg Female) within class labels $Y$ (\eg Programmers). This dataset bias can lead to models that learn spurious correlations between class…

Computer Vision and Pattern Recognition · Computer Science 2023-04-28 Maan Qraitem , Kate Saenko , Bryan A. Plummer

An automated segmentation and classification of nuclei is an essential task in digital pathology. The current deep learning-based approaches require a vast amount of annotated datasets by pathologists. However, the existing datasets are…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Tan Nhu Nhat Doan , Kyungeun Kim , Boram Song , Jin Tae Kwak

Small, imbalanced datasets and poor input image quality can lead to high false predictions rates with deep learning models. This paper introduces Class-Based Image Composition, an approach that allows us to reformulate training inputs…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Hlali Azzeddine , Majid Ben Yakhlef , Soulaiman El Hazzat

Automated detection and classification of cervical cells in conventional Pap smear images can strengthen cervical cancer screening at scale by reducing manual workload, improving triage, and increasing consistency across readers. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Lautaro Kogan , María Victoria Ríos

Class imbalance is a problem of significant importance in applied deep learning where trained models are exploited for decision support and automated decisions in critical areas such as health and medicine, transportation, and finance. The…

Machine Learning · Computer Science 2020-12-07 Colin Bellinger , Roberto Corizzo , Nathalie Japkowicz

Automatic blood vessel segmentation from retinal images plays an important role in the diagnosis of many systemic and eye diseases, including retinopathy of prematurity. Current state-of-the-art research in blood vessel segmentation from…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Gorana Gojić , Veljko Petrović , Radovan Turović , Dinu Dragan , Ana Oros , Dušan Gajić , Nebojša Horvat

Data imbalance is a well-known issue in the field of machine learning, attributable to the cost of data collection, the difficulty of labeling, and the geographical distribution of the data. In computer vision, bias in data distribution…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Shubham Shrivastava , Xianling Zhang , Sushruth Nagesh , Armin Parchami

The task of medical image segmentation presents unique challenges, necessitating both localized and holistic semantic understanding to accurately delineate areas of interest, such as critical tissues or aberrant features. This complexity is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Pranav Singh , Luoyao Chen , Mei Chen , Jinqian Pan , Raviteja Chukkapalli , Shravan Chaudhari , Jacopo Cirrone

Medical image data are usually imbalanced across different classes. One-class classification has attracted increasing attention to address the data imbalance problem by distinguishing the samples of the minority class from the majority…

Image and Video Processing · Electrical Eng. & Systems 2022-04-15 Long Gao , Chang Liu , Dooman Arefan , Ashok Panigrahy , Shandong Wu

Despite extensive research spanning several decades, class imbalance is still considered a profound difficulty for both machine learning and deep learning models. While data oversampling is the foremost technique to address this issue,…

Machine Learning · Computer Science 2025-02-12 Sukumar Kishanthan , Asela Hevapathige

Biomedical data are widely accepted in developing prediction models for identifying a specific tumor, drug discovery and classification of human cancers. However, previous studies usually focused on different classifiers, and overlook the…

Quantitative Methods · Quantitative Biology 2019-11-05 Shigang Liu , Jun Zhang , Yang Xiang , Wanlei Zhou , Dongxi Xiang

Breast Cancer is the most common cancer among women, which is also visible in men, and accounts for more than 1 in 10 new cancer diagnoses each year. It is also the second most common cause of women who die from cancer. Hence, it…

Image and Video Processing · Electrical Eng. & Systems 2023-10-17 Kanan Mahammadli , Abdullah Burkan Bereketoglu , Ayse Gul Kabakci

Medical imaging datasets are often characterized by extreme class imbalances, where rare pathologies are significantly underrepresented compared to common conditions. This imbalance poses a dual challenge for Open-Set Recognition (OSR):…

Computer Vision and Pattern Recognition · Computer Science 2026-05-04 Vishal , Arnav Aditya , Nitin Kumar , Saurabh J. Shigwan

Deep learning approaches are successful in a wide range of AI problems and in particular for visual recognition tasks. However, there are still open problems among which is the capacity to handle streams of visual information and the…

Machine Learning · Computer Science 2022-02-02 Umang Aggarwal , Adrian Popescu , Eden Belouadah , Céline Hudelot

The accurate classification of white blood cells and related blood components is crucial for medical diagnoses. While traditional manual examinations and automated hematology analyzers have been widely used, they are often slow and prone to…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Alexander Kim , Ryan Kim

Modeling of the red blood cell (RBC) shape is an integral part of the experimental and computer simulation investigations of light scattering by these cells for fundamental studies as well as diagnostic applications in techniques like…

Biological Physics · Physics 2024-06-18 Gaurav D. Bhabhor , Chetna Patel , Nishant Chhillar , Arun Anand , Kirit N. Lad
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