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The rapid spread of the Coronavirus SARS-2 is a major challenge that led almost all governments worldwide to take drastic measures to respond to the tragedy. Chief among those measures is the massive lockdown of entire countries and cities,…

Computers and Society · Computer Science 2020-06-15 Salah Ghamizi , Renaud Rwemalika , Lisa Veiber , Maxime Cordy , Tegawende F. Bissyande , Mike Papadakis , Jacques Klein , Yves Le Traon

Compartmental models like the Susceptible-Infected-Recovered (SIR)\cite{Kermack1927} and its extensions such as the Susceptible-Exposed-Infected-Recovered (SEIRS)\cite{Ottar2020,Ignazio2021,Grimm2021,Paoluzzi2021} are commonly used to model…

Populations and Evolution · Quantitative Biology 2025-07-14 Kasturi Banerjee , Subhankar Ray , Jayalakshmi Shamanna

This paper develops an individual-based stochastic network SIR model for the empirical analysis of the Covid-19 pandemic. It derives moment conditions for the number of infected and active cases for single as well as multigroup epidemic…

Econometrics · Economics 2022-01-05 M. Hashem Pesaran , Cynthia Fan Yang

We study the SIR epidemiological model, with a variable contagion rate, applied to the evolution of COVID19 in Cuba. It is highlighted that an increase in the predictive character depends on understanding the dynamics for the temporal…

Populations and Evolution · Quantitative Biology 2020-04-24 Nana Cabo Bizet , Alejandro Cabo Montes de Oca

Analysing and understanding the transmission and evolution of the COVID-19 pandemic is mandatory to be able to design the best social and medical policies, foresee their outcomes and deal with all the subsequent socio-economic effects. We…

Populations and Evolution · Quantitative Biology 2025-07-28 Radu D. Stochiţoiu , Marian Petrica , Traian Rebedea , Ionel Popescu , Marius Leordeanu

In this paper, we consider an adaptive optimal control problem for an SIR/V epidemic model with human behavioral effects.We develop a model where effective management of infectious diseases are monitored by the means of non pharmaceutical…

Physics and Society · Physics 2025-12-09 Nuruzzaman Rahat , Abid Hossain , Muntasir Alam

We propose and study a compartmental model for epidemiology with human behavioral effects. Specifically, our model incorporates governmental prevention measures aimed at lowering the disease infection rate, but we split the population into…

Systems and Control · Electrical Eng. & Systems 2026-02-16 Chloe Ngo , Christian Parkinson , Weinan Wang

In this paper, an SIR epidemic model with variable size of population is considered. We study optimal control problem for an SIR model with "vaccination" and "treatment" as controls. It is shown that an optimal control exists. We have…

Optimization and Control · Mathematics 2016-12-28 Olga Klimenkova

In this paper, we introduce a new control-theoretic paradigm for mitigating the spread of a virus. To this end, our discrete-time controller, aims to reduce the number of new daily deaths, and consequently, the cumulative number of deaths.…

Populations and Evolution · Quantitative Biology 2020-08-17 Kevin Burke , B. Ross Barmish

We present a new mathematical model to explicitly capture the effects that the three restriction measures: the lockdown date and duration, social distancing and masks, and, schools and border closing, have in controlling the spread of…

Populations and Evolution · Quantitative Biology 2020-08-25 Liam Dowling Jones , Malik Magdon-Ismail , Laura Mersini-Houghton , Steven Meshnick

We examine the age-structured SIR model, a variant of the classical Susceptible-Infected-Recovered (SIR) model of epidemic propagation, in the context of COVID-19. In doing so, we provide a theoretical basis for the model, perform an…

Optimization and Control · Mathematics 2022-03-11 Rohit Parasnis , Ryosuke Kato , Amol Sakhale , Massimo Franceschetti , Behrouz Touri

This paper presents a vaccination-based control strategy for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total population amounts as a refrain for…

Dynamical Systems · Mathematics 2011-03-28 M. De la Sen , A. Ibeas , S. Alonso-Quesada

In this paper, we investigate the distributed link removal strategy for networked meta-population epidemics. In particular, a deterministic networked susceptible-infected-recovered (SIR) model is considered to describe the epidemic evolving…

Physics and Society · Physics 2020-06-30 Fangzhou Liu , Yuhong Chen , Tong Liu , Zibo Zhou , Dong Xue , Martin Buss

This study aims to determine an optimal control strategy for vaccine scheduling in COVID-19 pandemic treatment by converting widely acknowledged infectious disease model named SEIR into an optimal control problem. The problem is augmented…

Populations and Evolution · Quantitative Biology 2020-08-26 Syed Irfan Ali Meerza , Seyed M. Karimi , Bert B. Little , Jacek M. Zurada , Tamer Inanc

We study the datafor the cumulative as well as daily number of cases in the Covid-19 outbreak in China. The cumulative data can be fit to an empirical form obtained from a Susceptible-Infected-Removed (SIR) model studied on an Euclidean…

Physics and Society · Physics 2020-03-17 Kathakali Biswas , Abdul Khaleque , Parongama Sen

This work focuses on optimal controls of a class of stochastic SIS epidemic models under regime switching. By assuming that a decision maker can either influence the infectivity period or isolate infected individuals, our aim is to minimize…

Optimization and Control · Mathematics 2021-01-12 Ky Tran , George Yin

The growing literature on the propagation of COVID-19 relies on various dynamic SIR-type models (Susceptible-Infected-Recovered) which yield model-dependent results. For transparency and ease of comparing the results, we introduce a common…

Populations and Evolution · Quantitative Biology 2020-06-19 Christian Gourieroux , Joann Jasiak

Based on the classical SIR model, we derive a simple modification for the dynamics of epidemics with a known incubation period of infection. The model is described by a system of integro-differential equations. Parameters of our model…

Populations and Evolution · Quantitative Biology 2021-09-01 David B. Saakian

We study Susceptible-Exposed-Asymptomatic-Infectious-Recovered (SEAIR) epidemic spreading model of COVID-19. It captures two important characteristics of the infectiousness of COVID-19: delayed start and its appearance before onset of…

Physics and Society · Physics 2021-02-03 Lasko Basnarkov

We propose a simple SIR model in order to investigate the impact of various confinement strategies on a most virulent epidemic. Our approach is motivated by the current COVID-19 pandemic. The main hypothesis is the existence of two…

Populations and Evolution · Quantitative Biology 2020-12-30 G. Nakamura , B. Grammaticos , M. Badoual