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In this study, we propose a time-dependent Susceptible-Exposed-Infected-Recovered (SEIR) model for the analysis of the SARS-CoV-2 epidemic outbreak in three different countries, the United States of America, Italy and Iceland using public…

Populations and Evolution · Quantitative Biology 2021-11-08 P. Girardi , C. Gaetan

Traditionally, the identification of parameters in the formulation and solution of inverse problems considers that models, variables and mathematical parameters are free of uncertainties. This aspect simplifies the estimation process, but…

Populations and Evolution · Quantitative Biology 2020-06-02 Gustavo Barbosa Libotte , Fran Sérgio Lobato , Gustavo Mendes Platt

Mathematical models of infectious diseases exhibit robust dynamics such as stable endemic or a disease-free equilibrium, or convergence of the solutions to periodic epidemic waves. The present work shows that the accuracy of such dynamics…

Applications · Statistics 2022-05-04 Hadeel AlQadi , Majid Bani-Yaghoub

With the outbreak of COVID-19, how to mitigate and suppress its spread is a big issue to the government. Department of public health need powerful models to model and predict the trend and scale of such pandemic. And models that could…

Computational Engineering, Finance, and Science · Computer Science 2020-12-08 Wang Pan , Qipu Deng , Jiadong Li , Zhi Wang , Wenwu Zhu

In this paper, we conduct mathematical and numerical analyses to address the following crucial questions for COVID-19: (Q1) Is it possible to contain COVID-19? (Q2) When will be the peak and the end of the epidemic? (Q3) How do the…

Populations and Evolution · Quantitative Biology 2020-09-22 Yi-Cheng Chen , Ping-En Lu , Cheng-Shang Chang , Tzu-Hsuan Liu

In this research paper we modify a classical SIR model to better adapt to the dynamics of COVID-19, that is we propose the heterogeneous SQAIRD model where COVID-19 spreads over a population of economic agents, namely: the elderly, adults…

Optimization and Control · Mathematics 2021-05-19 Elena Gubar , Laura Policardo , Edgar J. Sanchez Carrera , Vladislav Taynitskiy

In this work we present a mathematical model that integrates the epidemiological dynamics of a vector-borne disease (SIR-SI) with Lotka Volterra predator prey ecological interactions. The study analyzes how the presence of natural predators…

Optimization and Control · Mathematics 2026-02-09 Rocio Balderrama , Ignacio Ceresa Dussel , Constanza Sanchez de la Vega

In this paper, we present a Distributionally Robust Markov Decision Process (DRMDP) approach for addressing the dynamic epidemic control problem. The Susceptible-Exposed-Infectious-Recovered (SEIR) model is widely used to represent the…

Optimization and Control · Mathematics 2023-06-27 Jun Song , William Yang , Chaoyue Zhao

Throughout human history, epidemics have been a constant presence. Understanding their dynamics is essential to predict scenarios and make substantiated decisions. Mathematical models are powerful tools to describe an epidemic behavior.…

Systems and Control · Electrical Eng. & Systems 2024-07-26 Walter HMendes aselein , Diego Eckhard

Understanding how to effectively control an epidemic spreading on a network is a problem of paramount importance for the scientific community. The ongoing COVID-19 pandemic has highlighted the need for policies that mitigate the spread,…

Populations and Evolution · Quantitative Biology 2021-09-14 Carlo Cenedese , Lorenzo Zino , Michele Cucuzzella , Ming Cao

In this paper, we derive a version of the Pontryagin maximum principle for general finite-dimensional nonlinear optimal sampled-data control problems. Our framework is actually much more general, and we treat optimal control problems for…

Optimization and Control · Mathematics 2015-12-09 Loïc Bourdin , Emmanuel Trélat

The coronavirus pandemic has rapidly evolved into an unprecedented crisis. The susceptible-infectious-removed (SIR) model and its variants have been used for modeling the pandemic. However, time-independent parameters in the classical…

Populations and Evolution · Quantitative Biology 2020-09-09 Hyokyoung G. Hong , Yi Li

The fast transmission rate of COVID-19 worldwide has made this virus the most important challenge of year 2020. Many mitigation policies have been imposed by the governments at different regional levels (country, state, county, and city) to…

Applications · Statistics 2022-05-04 Yue Bai , Abolfazl Safikhani , George Michailidis

We investigate the time-optimal control problem in SIR (Susceptible-Infected-Recovered) epidemic models, focusing on different control policies: vaccination, isolation, culling, and reduction of transmission. Applying the Pontryagin's…

Optimization and Control · Mathematics 2017-06-15 Luca Bolzoni , Elena Bonacini , Cinzia Soresina , Maria Groppi

We investigate, through a fractional mathematical model, the effects of physical distance on the SARS-CoV-2 virus transmission. Two controls are considered in our model for eradication of the spread of COVID-19: media education, through…

Optimization and Control · Mathematics 2021-03-02 Samia Bushnaq , Tareq Saeed , Delfim F. M. Torres , Anwar Zeb

The infections and fatalities due to SARS-CoV-2 virus for cases specific to India have been studied using a deterministic susceptible-exposed-infected-recovered-dead (SEIRD) compartmental model. One of the most significant epidemiological…

Populations and Evolution · Quantitative Biology 2020-06-09 Vishwajeet Jha

In this work, we develop a spatial SEIAR-type epidemic model considering a quarantined population (denoted as Q), which we call the SQEIAR model. The dynamics of the SQEIAR model are described by six Partial Differential Equations (PDEs)…

Dynamical Systems · Mathematics 2025-01-27 Elghandouri Mohammed , Ezzinbi Khalil , Youness Mezzan

We study the dynamic evolution of COVID-19 cased by the Omicron variant via a fractional susceptible-exposedinfected-removed (SEIR) model. Preliminary data suggest that the symptoms of Omicron infection are not prominent and the…

Numerical Analysis · Mathematics 2022-07-21 Min Cai , George Em Karniadakis , Changpin Li

Recent Covid-19 pandemic has demonstrated the need of efficient epidemic outbreak management. We study the optimal control problem of minimizing the fraction of infected population by applying vaccination and treatment control strategies,…

Social and Information Networks · Computer Science 2021-12-07 Jagtap Kalyani Devendra , Kundan Kandhway

This paper proposes a feedback design that effectively copes with uncertainties for reliable epidemic monitoring and control. There are several optimization-based methods to estimate the parameters of an epidemic model by utilizing past…

Optimization and Control · Mathematics 2023-04-06 Muhammad Umar B. Niazi , Philip E. Paré , Karl H. Johansson
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