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A central goal of unsupervised learning is to acquire representations from unlabeled data or experience that can be used for more effective learning of downstream tasks from modest amounts of labeled data. Many prior unsupervised learning…

Machine Learning · Computer Science 2019-03-25 Kyle Hsu , Sergey Levine , Chelsea Finn

Recently, the self-supervised pre-training paradigm has shown great potential in leveraging large-scale unlabeled data to improve downstream task performance. However, increasing the scale of unlabeled pre-training data in real-world…

Computer Vision and Pattern Recognition · Computer Science 2022-12-13 Yiqi Lin , Huabin Zheng , Huaping Zhong , Jinjing Zhu , Weijia Li , Conghui He , Lin Wang

For sequence transduction tasks like speech recognition, a strong structured prior model encodes rich information about the target space, implicitly ruling out invalid sequences by assigning them low probability. In this work, we propose…

Computation and Language · Computer Science 2020-02-25 Wei-Ning Hsu , Ann Lee , Gabriel Synnaeve , Awni Hannun

Pre-training models on vast quantities of unlabeled data has emerged as an effective approach to improving accuracy on many NLP tasks. On the other hand, traditional machine translation has a long history of leveraging unlabeled data…

Computation and Language · Computer Science 2020-11-17 Shruti Bhosale , Kyra Yee , Sergey Edunov , Michael Auli

Motivation: Drug discovery demands rapid quantification of compound-protein interaction (CPI). However, there is a lack of methods that can predict compound-protein affinity from sequences alone with high applicability, accuracy, and…

Biomolecules · Quantitative Biology 2020-12-17 Mostafa Karimi , Di Wu , Zhangyang Wang , Yang Shen

Language models (LMs) are pretrained to imitate internet text, including content that would violate human preferences if generated by an LM: falsehoods, offensive comments, personally identifiable information, low-quality or buggy code, and…

Computation and Language · Computer Science 2023-06-16 Tomasz Korbak , Kejian Shi , Angelica Chen , Rasika Bhalerao , Christopher L. Buckley , Jason Phang , Samuel R. Bowman , Ethan Perez

Current protein language models (PLMs) learn protein representations mainly based on their sequences, thereby well capturing co-evolutionary information, but they are unable to explicitly acquire protein functions, which is the end goal of…

Biomolecules · Quantitative Biology 2023-07-06 Minghao Xu , Xinyu Yuan , Santiago Miret , Jian Tang

Curriculum learning-organizing training data from easy to hard-has improved efficiency across machine learning domains, yet remains underexplored for language model pretraining. We present the first systematic investigation of curriculum…

Computation and Language · Computer Science 2026-01-29 Yang Zhang , Amr Mohamed , Hadi Abdine , Guokan Shang , Michalis Vazirgiannis

The significant achievements of pre-trained models leveraging large volumes of data in the field of NLP and 2D vision inspire us to explore the potential of extensive data pre-training for 3D perception in autonomous driving. Toward this…

Computer Vision and Pattern Recognition · Computer Science 2025-04-18 Shumin Wang , Zhuoran Yang , Lidian Wang , Zhipeng Tang , Heng Li , Lehan Pan , Sha Zhang , Jie Peng , Jianmin Ji , Yanyong Zhang

Transductive learning is a supervised machine learning task in which, unlike in traditional inductive learning, the unlabelled data that require labelling are a finite set and are available at training time. Similarly to inductive learning…

Machine Learning · Computer Science 2025-07-31 Lorenzo Volpi , Alejandro Moreo , Fabrizio Sebastiani

Few-shot learning benchmarks are critical for evaluating modern NLP techniques. It is possible, however, that benchmarks favor methods which easily make use of unlabeled text, because researchers can use unlabeled text from the test set to…

Computation and Language · Computer Science 2024-10-03 Kush Dubey

In this paper we present a novel Neural Network algorithm for conducting semi-supervised learning for sequence labeling tasks arranged in a linguistically motivated hierarchy. This relationship is exploited to regularise the representations…

Computation and Language · Computer Science 2016-12-30 Jonathan Godwin , Pontus Stenetorp , Sebastian Riedel

Training models on low-resource named entity recognition tasks has been shown to be a challenge, especially in industrial applications where deploying updated models is a continuous effort and crucial for business operations. In such cases…

Computation and Language · Computer Science 2019-10-18 Peter Izsak , Shira Guskin , Moshe Wasserblat

Instruction tuning enhances large language models (LLMs) to follow human instructions across diverse tasks, relying on high-quality datasets to guide behavior. However, these datasets, whether manually curated or synthetically generated,…

Protein-DNA interaction is critical for life activities such as replication, transcription, and splicing. Identifying protein-DNA binding residues is essential for modeling their interaction and downstream studies. However, developing…

Biomolecules · Quantitative Biology 2023-06-29 Yufan Liu , Boxue Tian

Foundation models in healthcare have largely adopted self supervised pretraining objectives inherited from natural language processing and computer vision, emphasizing reconstruction and large scale representation learning prior to…

Machine Learning · Computer Science 2026-03-24 Yang Zhang , Li Fan , Samuel Lawrence , Shi Li

This paper surveys and organizes research works in a new paradigm in natural language processing, which we dub "prompt-based learning". Unlike traditional supervised learning, which trains a model to take in an input x and predict an output…

Computation and Language · Computer Science 2021-07-30 Pengfei Liu , Weizhe Yuan , Jinlan Fu , Zhengbao Jiang , Hiroaki Hayashi , Graham Neubig

Natural language processing (NLP) tasks tend to suffer from a paucity of suitably annotated training data, hence the recent success of transfer learning across a wide variety of them. The typical recipe involves: (i) training a deep,…

Computation and Language · Computer Science 2019-09-11 Lyan Verwimp , Jerome R. Bellegarda

Pretrained language models (PLMs) display impressive performances and have captured the attention of the NLP community. Establishing best practices in pretraining has, therefore, become a major focus of NLP research, especially since…

Computation and Language · Computer Science 2024-10-08 Zihao Li , Shaoxiong Ji , Timothee Mickus , Vincent Segonne , Jörg Tiedemann

Protein language models (pLMs) have recently gained significant attention for their ability to uncover relationships between sequence, structure, and function from evolutionary statistics, thereby accelerating therapeutic drug discovery.…

Machine Learning · Computer Science 2026-03-04 Darshan Patil , Pranshu Malviya , Mathieu Reymond , Quentin Fournier , Sarath Chandar