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Deformable registration is crucial in medical imaging. Several existing applications include lesion tracking, probabilistic atlas generation, and treatment response evaluation. However, current methods often lack robustness and…

Image and Video Processing · Electrical Eng. & Systems 2026-03-04 Yunzheng Zhu , Aichi Chien , Kimaya kulkarni , Luoting Zhuang , Stephen Park , Ricky Savjani , Daniel Low , William Hsu

In this work, we consider the task of pairwise cross-modality image registration, which may benefit from exploiting additional images available only at training time from an additional modality that is different to those being registered.…

Computer Vision and Pattern Recognition · Computer Science 2022-07-27 Qianye Yang , David Atkinson , Yunguan Fu , Tom Syer , Wen Yan , Shonit Punwani , Matthew J. Clarkson , Dean C. Barratt , Tom Vercauteren , Yipeng Hu

We present deformable unsupervised medical image registration using a randomly-initialized deep convolutional neural network (CNN) as regularization prior. Conventional registration methods predict a transformation by minimizing…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier

Image registration is essential for medical image applications where alignment of voxels across multiple images is needed for qualitative or quantitative analysis. With recent advancements in deep neural networks and parallel computing,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-23 Yi Zhang , Yidong Zhao , Hui Xue , Peter Kellman , Stefan Klein , Qian Tao

Patient specific brain mesh generation from MRI can be a time consuming task and require manual corrections, e.g., for meshing the ventricular system or defining subdomains. To address this issue, we consider an image registration approach.…

Numerical Analysis · Mathematics 2024-04-10 Bastian Zapf , Johannes Haubner , Lukas Baumgärtner , Stephan Schmidt

In the field of medical image analysis, image registration is a crucial technique. Despite the numerous registration models that have been proposed, existing methods still fall short in terms of accuracy and interpretability. In this paper,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-25 Jiaofen Nan , Gaodeng Fan , Kaifan Zhang , Chen Zhao , Fubao Zhu , Weihua Zhou

This paper presents a generic probabilistic framework for estimating the statistical dependency and finding the anatomical correspondences among an arbitrary number of medical images. The method builds on a novel formulation of the…

Computer Vision and Pattern Recognition · Computer Science 2022-12-13 Xinzhe Luo , Xiahai Zhuang

Deformable registration has been one of the pillars of biomedical image computing. Conventional approaches refer to the definition of a similarity criterion that, once endowed with a deformation model and a smoothness constraint, determines…

Computer Vision and Pattern Recognition · Computer Science 2018-09-25 Enzo Ferrante , Puneet K. Dokania , Rafael Marini Silva , Nikos Paragios

Functional magnetic resonance imaging (fMRI) has provided invaluable insight into our understanding of human behavior. However, large inter-individual differences in both brain anatomy and functional localization after anatomical alignment…

Applications · Statistics 2021-11-03 Guoqing Wang , Abhirup Datta , Martin A. Lindquist

We present a mutual information-based framework for unsupervised image-to-image translation. Our MCMI approach treats single-cycle image translation models as modules that can be used recurrently in a multi-cycle translation setting where…

Computer Vision and Pattern Recognition · Computer Science 2020-07-07 Xiang Xu , Megha Nawhal , Greg Mori , Manolis Savva

In clinical practice, well-aligned multi-modal images, such as Magnetic Resonance (MR) and Computed Tomography (CT), together can provide complementary information for image-guided therapies. Multi-modal image registration is essential for…

Computer Vision and Pattern Recognition · Computer Science 2022-04-29 Zekang Chen , Jia Wei , Rui Li

Parametric spatial transformation models have been successfully applied to image registration tasks. In such models, the transformation of interest is parameterized by a fixed set of basis functions as for example B-splines. Each basis…

Computer Vision and Pattern Recognition · Computer Science 2019-06-25 Robin Sandkühler , Simon Andermatt , Grzegorz Bauman , Sylvia Nyilas , Christoph Jud , Philippe C. Cattin

The deformable registration of images of different modalities, essential in many medical imaging applications, remains challenging. The main challenge is developing a robust measure for image overlap despite the compared images capturing…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Joel Honkamaa , Pekka Marttinen

We tackle here the problem of multimodal image non-rigid registration, which is of prime importance in remote sensing and medical imaging. The difficulties encountered by classical registration approaches include feature design and slow…

Computer Vision and Pattern Recognition · Computer Science 2018-02-28 Armand Zampieri , Guillaume Charpiat , Yuliya Tarabalka

Analyzing and predicting brain aging is essential for early prognosis and accurate diagnosis of cognitive diseases. The technique of neuroimaging, such as Magnetic Resonance Imaging (MRI), provides a noninvasive means of observing the aging…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Jingru Fu , Antonios Tzortzakakis , José Barroso , Eric Westman , Daniel Ferreira , Rodrigo Moreno

Reliably and physically accurately transferring information between images through deformable image registration with large anatomical differences is an open challenge in medical image analysis. Most existing methods have two key…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Georgios Andreadis , Peter A. N. Bosman , Tanja Alderliesten

Image registration has traditionally been done using two distinct approaches: learning based methods, relying on robust deep neural networks, and optimization-based methods, applying complex mathematical transformations to warp images…

Computer Vision and Pattern Recognition · Computer Science 2024-01-22 Gabriel De Araujo , Shanlin Sun , Xiaohui Xie

Affine registration is indispensable in a comprehensive medical image registration pipeline. However, only a few studies focus on fast and robust affine registration algorithms. Most of these studies utilize convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2022-03-31 Tony C. W. Mok , Albert C. S. Chung

Diffusion models for Text-to-Image (T2I) conditional generation have recently achieved tremendous success. Yet, aligning these models with user's intentions still involves a laborious trial-and-error process, and this challenging alignment…

Machine Learning · Computer Science 2025-02-12 Chao Wang , Giulio Franzese , Alessandro Finamore , Massimo Gallo , Pietro Michiardi

We develop the use of mutual information (MI), a well-established metric in information theory, to interpret the inner workings of deep learning models. To accurately estimate MI from a finite number of samples, we present GMM-MI…

Data Analysis, Statistics and Probability · Physics 2023-04-12 Davide Piras , Hiranya V. Peiris , Andrew Pontzen , Luisa Lucie-Smith , Ningyuan Guo , Brian Nord
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