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In clinical practice, imaging modalities with functional characteristics, such as positron emission tomography (PET) and fractional anisotropy (FA), are often aligned with a structural reference (e.g., MRI, CT) for accurate interpretation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Kyobin Choo , Hyunkyung Han , Jinyeong Kim , Chanyong Yoon , Seong Jae Hwang

Motivation: High resolution 2D whole slide imaging provides rich information about the tissue structure. This information can be a lot richer if these 2D images can be stacked into a 3D tissue volume. A 3D analysis, however, requires…

The ability of machine learning (ML) algorithms to generalize well to unseen data has been studied through the lens of information theory, by bounding the generalization error with the input-output mutual information (MI), i.e., the MI…

Machine Learning · Statistics 2024-06-07 Kimia Nadjahi , Kristjan Greenewald , Rickard Brüel Gabrielsson , Justin Solomon

We propose a registration algorithm for 2D CT/MRI medical images with a new unsupervised end-to-end strategy using convolutional neural networks. The contributions of our algorithm are threefold: (1) We transplant traditional image…

Computer Vision and Pattern Recognition · Computer Science 2018-01-23 Siyuan Shan , Wen Yan , Xiaoqing Guo , Eric I-Chao Chang , Yubo Fan , Yan Xu

Generalized mutual information (GMI) is used to compute achievable rates for fading channels with various types of channel state information at the transmitter (CSIT) and receiver (CSIR). The GMI is based on variations of auxiliary channel…

Information Theory · Computer Science 2023-05-23 Gerhard Kramer

Semantic segmentation is a fundamental problem in computer vision. It is considered as a pixel-wise classification problem in practice, and most segmentation models use a pixel-wise loss as their optimization riterion. However, the…

Computer Vision and Pattern Recognition · Computer Science 2019-10-29 Shuai Zhao , Yang Wang , Zheng Yang , Deng Cai

Medical image registration is a critical component of clinical imaging workflows, enabling accurate longitudinal assessment, multi-modal data fusion, and image-guided interventions. Intensity-based approaches often struggle with…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Eytan Kats , Mattias P. Heinrich

This paper establishes an information theoretic framework for deep metric based image registration techniques. We show an exact equivalence between maximum profile likelihood and minimization of joint entropy, an important early information…

Computer Vision and Pattern Recognition · Computer Science 2019-01-03 Alireza Sedghi , Jie Luo , Alireza Mehrtash , Steve Pieper , Clare M. Tempany , Tina Kapur , Parvin Mousavi , William M. Wells

Surgical navigation based on multimodal image registration has played a significant role in providing intraoperative guidance to surgeons by showing the relative position of the target area to critical anatomical structures during surgery.…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Jiazheng Wang , Zeyu Liu , Min Liu , Xiang Chen , Xinyao Yu , Yaonan Wang , Hang Zhang

Radiotherapists require accurate registration of MR/CT images to effectively use information from both modalities. In a typical registration pipeline, rigid or affine transformations are applied to roughly align the fixed and moving images…

Computer Vision and Pattern Recognition · Computer Science 2023-07-10 Xiaoyu Bai , Fan Bai , Xiaofei Huo , Jia Ge , Tony C. W. Mok , Zi Li , Minfeng Xu , Jingren Zhou , Le Lu , Dakai Jin , Xianghua Ye , Jingjing Lu , Ke Yan

While medical imaging typically provides massive amounts of data, the extraction of relevant information for predictive diagnosis remains a difficult challenge. Functional MRI (fMRI) data, that provide an indirect measure of task-related or…

Computer Vision and Pattern Recognition · Computer Science 2011-02-22 Vincent Michel , Alexandre Gramfort , Gaël Varoquaux , Evelyn Eger , Bertrand Thirion

Accurate motion estimation at high acceleration factors enables rapid motion-compensated reconstruction in Magnetic Resonance Imaging (MRI) without compromising the diagnostic image quality. In this work, we introduce an attention-aware…

Image and Video Processing · Electrical Eng. & Systems 2024-04-30 Aya Ghoul , Jiazhen Pan , Andreas Lingg , Jens Kübler , Patrick Krumm , Kerstin Hammernik , Daniel Rueckert , Sergios Gatidis , Thomas Küstner

One of the fundamental elements of both traditional and certain deep learning medical image registration algorithms is measuring the similarity/dissimilarity between two images. In this work, we propose an analytical solution for measuring…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Mohammadreza Eskandari , Houssem-Eddine Gueziri , D. Louis Collins

Estimating mutual information (MI) between two continuous random variables $X$ and $Y$ allows to capture non-linear dependencies between them, non-parametrically. As such, MI estimation lies at the core of many data science applications.…

Information Theory · Computer Science 2022-01-19 Alexander Marx , Jonas Fischer

In this paper, we propose a novel method for image fusion with a high-resolution panchromatic image and a low-resolution multispectral image at the same geographical location. The fusion is formulated as a convex optimization problem which…

Computer Vision and Pattern Recognition · Computer Science 2015-10-28 Chen Chen , Yeqing Li , Wei Liu , Junzhou Huang

Deep learning-based deformable registration methods have been widely investigated in diverse medical applications. Learning-based deformable registration relies on weighted objective functions trading off registration accuracy and…

Image and Video Processing · Electrical Eng. & Systems 2023-07-21 Haoran Dou , Ning Bi , Luyi Han , Yuhao Huang , Ritse Mann , Xin Yang , Dong Ni , Nishant Ravikumar , Alejandro F. Frangi , Yunzhi Huang

This study introduces a novel On-the-Fly Guidance (OFG) training framework for enhancing existing learning-based image registration models, addressing the limitations of weakly-supervised and unsupervised methods. Weakly-supervised methods…

Computer Vision and Pattern Recognition · Computer Science 2024-07-15 Yuelin Xin , Yicheng Chen , Shengxiang Ji , Kun Han , Xiaohui Xie

In image-guided neurosurgery, current commercial systems usually provide only rigid registration, partly because it is harder to predict, validate and understand non-rigid registration error. For instance, when surgeons see a discrepancy in…

Computer Vision and Pattern Recognition · Computer Science 2020-03-24 Jie Luo , Sarah Frisken , Duo Wang , Alexandra Golby , Masashi Sugiyama , William M. Wells

Nonrigid registration is vital to medical image analysis but remains challenging for diffusion MRI (dMRI) due to its high-dimensional, orientation-dependent nature. While classical methods are accurate, they are computationally demanding,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-13 Gianfranco Cortes , Xiaoda Qu , Baba C. Vemuri

We describe a diffeomorphic registration algorithm that allows groups of images to be accurately aligned to a common space, which we intend to incorporate into the SPM software. The idea is to perform inference in a probabilistic graphical…

Computer Vision and Pattern Recognition · Computer Science 2021-05-10 Mikael Brudfors , Yaël Balbastre , Guillaume Flandin , Parashkev Nachev , John Ashburner
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