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The cardiovascular system is composed of the heart, blood and blood vessels. Regarding the heart, cardiac conditions are determined by the electrocardiogram, that is a noninvasive medical procedure. In this work, we propose autoregressive…

This work is concerned with modeling and simulation of the mitral valve, one of the four valves in the human heart. The valve is composed of leaflets, the free edges of which are supported by a system of chordae, which themselves are…

Tissues and Organs · Quantitative Biology 2020-11-19 Alexander D. Kaiser , David M. McQueen , Charles S. Peskin

An electrocardiogram (EKG) is a common, non-invasive test that measures the electrical activity of a patient's heart. EKGs contain useful diagnostic information about patient health that may be absent from other electronic health record…

Machine Learning · Statistics 2018-12-04 Andrew C. Miller , Ziad Obermeyer , David M. Blei , John P. Cunningham , Sendhil Mullainathan

Cardiovascular modeling has rapidly advanced over the past few decades due to the rising needs for health tracking and early detection of cardiovascular diseases. While 1-D arterial models offer an attractive compromise between…

Cardiovascular disease affects millions of people worldwide and its social and economic cost clearly motivates scientific research. Computer simulation can lead to a better understanding of cardiac physiology, and for pathology presents…

Biological Physics · Physics 2023-02-27 Toby Simpson

Sharing a common clock signal among the nodes is crucial for communication in synchronized networks. This work presents a heartbeat-based synchronization scheme for body-worn nodes. The principles of this coordination technique combined…

Networking and Internet Architecture · Computer Science 2020-05-13 Robin Benarrouch , Ali Moin , Flavien Solt , Antoine Frappé , Andreia Cathelin , Andreas Kaiser , Jan Rabaey

Previous models of the cerebrovascular smooth muscle cell have not addressed the interaction between the electrical, chemical and mechanical components of cell function during the development of active tension. These models are primarily…

Cell Behavior · Quantitative Biology 2013-03-27 Jin Yang , John W. Clark , Robert M. Bryan , Claudia S. Robertson

Accurate and efficient modeling of cardiac blood flow is crucial for advancing data-driven tools in cardiovascular research and clinical applications. Recently, the accuracy and availability of computational fluid dynamics (CFD)…

Fluid Dynamics · Physics 2025-07-30 Eneko Lazpita , Jesus Garicano-Mena , Soledad Le Clainche

Our evolving understanding of the heterocellular cardiac environment demands innovative tools for its study. While murine models are lauded for their versatility and accessibility, they are constrained by scale; tools designed for larger…

Biological Physics · Physics 2023-12-12 Gavin Tumlinson , Enaam Chleilat , Josef Madl , Peter Kohl , Viviane Timmermann

Accurate assessment of intraventricular blood flow is essential for evaluating hemodynamic conditions in patients supported by Left Ventricular Assist Devices (LVADs). However, clinical imaging is either incompatible with LVADs or yields…

We develop two mathematical lumped parameter models for blood pressure distribution in the Fontan blood flow circulation: an ODE based spatially homogeneous model and a PDE based spatially inhomogeneous model. We present numerical…

Analysis of PDEs · Mathematics 2018-06-08 J. P. Keener , M. Chugunova , R. M. Taranets , M. G. Doyle

The exploitation of large-scale population data has the potential to improve healthcare by discovering and understanding patterns and trends within this data. To enable high throughput analysis of cardiac imaging data automatically, a…

Image and Video Processing · Electrical Eng. & Systems 2019-01-14 Rahman Attar , Marco Pereanez , Ali Gooya , Xenia Alba , Le Zhang , Stefan K. Piechnik , Stefan Neubauer , Steffen E. Petersen , Alejandro F. Frangi

Volume conductor problems in cerebral electrophysiology and bioimpedance do not have analytical solutions for nontrivial geometries and require a 3D model of the head and its electrical properties for solving the associated PDEs…

Medical Physics · Physics 2021-11-02 Fernando S Moura , Roberto G Beraldo , Leonardo A Ferreira , Samuli Siltanen

The rapid developments in advanced sensing and imaging bring about a data-rich environment, facilitating the effective modeling, monitoring, and control of complex systems. For example, the body-sensor network captures multi-channel…

Machine Learning · Computer Science 2022-02-01 Jianxin Xie , Bing Yao

We report three-dimensional and time-dependent numerical simulations of the propagation of electrical action potentials in a model of rabbit ventricular tissue. The simulations are performed using a finite-element method for the solution of…

Quantitative Methods · Quantitative Biology 2021-05-20 Peter Mortensen , Muhamad H. N. Aziz , Hao Gao , Radostin D. Simitev

External matching networks are crucial and necessary for operating capacitively coupled plasmas in order to maximize the absorbed power. Experiments show that external circuits in general heavily interact with the plasma in a nonlinear way.…

Plasma Physics · Physics 2018-11-15 Frederik Schmidt , Thomas Mussenbrock , Jan Trieschmann

Computational fluid dynamics (CFD) is an important tool for the simulation of the cardiovascular function and dysfunction. Due to the complexity of the anatomy, the transitional regime of blood flow in the heart, and the strong mutual…

The human heart is a sophisticated system composed of four cardiac chambers with distinct shapes, which function in a coordinated manner. Existing shape models of the heart mainly focus on the ventricular chambers and they are derived from…

Image and Video Processing · Electrical Eng. & Systems 2026-03-31 Qiang Ma , Qingjie Meng , Yicheng Wu , Shuo Wang , Mengyun Qiao , Steven Niederer , Declan P. O'Regan , Paul M. Matthews , Wenjia Bai

Computational fluid dynamics (CFD) is increasingly used to study blood flows in patient-specific arteries for understanding certain cardiovascular diseases. The techniques work quite well for relatively simple problems, but need…

Computational Physics · Physics 2018-10-11 Fande Kong , Vitaly Kheyfets , Ender Finol , Xiao-Chuan Cai

Left ventricular (LV) function is an important factor in terms of patient management, outcome, and long-term survival of patients with heart disease. The most recently published clinical guidelines for heart failure recognise that over…