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Printing custom DNA sequences is essential to scientific and biomedical research, but the technology can be used to manufacture plagues as well as cures. Just as ink printers recognize and reject attempts to counterfeit money, DNA…

Backdoor attacks, representing an emerging threat to the integrity of deep neural networks, have garnered significant attention due to their ability to compromise deep learning systems clandestinely. While numerous backdoor attacks occur…

Cryptography and Security · Computer Science 2024-03-18 Sze Jue Yang , Chinh D. La , Quang H. Nguyen , Kok-Seng Wong , Anh Tuan Tran , Chee Seng Chan , Khoa D. Doan

Access to genomic data is highly regulated due to its sensitive nature. While safeguards are essential, cumbersome data access processes pose a significant barrier to the development of AI methods for genomics. Synthetic data generation can…

Cryptography and Security · Computer Science 2026-05-01 Daniil Filienko , Martine De Cock , Sikha Pentyala

In this work, we investigate the concept of biometric backdoors: a template poisoning attack on biometric systems that allows adversaries to stealthily and effortlessly impersonate users in the long-term by exploiting the template update…

Cryptography and Security · Computer Science 2020-11-06 Giulio Lovisotto , Simon Eberz , Ivan Martinovic

The rapid adoption of generative artificial intelligence (GenAI) in the biosciences is transforming biotechnology, medicine, and synthetic biology. Yet this advancement is intrinsically linked to new vulnerabilities, as GenAI lowers the…

The design of genetic networks with specific functions is one of the major goals of synthetic biology. However, constructing biological devices that work "as required" remains challenging, while the cost of uncovering flawed designs…

Systems and Control · Computer Science 2011-11-10 Boyan Yordanov , Calin Belta

This article uses Deep Learning technologies to safeguard DNA sequencing against Bio-Cyber attacks. We consider a hybrid attack scenario where the payload is encoded into a DNA sequence to activate a Trojan malware implanted in a software…

Synthetic biology is a growing interdisciplinary field, with far-reaching applications, which aims to design biochemical systems that behave in a desired manner. With the advancement of strand-displacement DNA computing, a large class of…

Molecular Networks · Quantitative Biology 2017-06-21 Tomislav Plesa , Konstantinos C. Zygalakis , David F. Anderson , Radek Erban

Cybersecurity is a crucial step in data protection to ensure user security and personal data privacy. In this sense, many companies have started to control and restrict access to their data using authentication systems. However, these…

Cryptography and Security · Computer Science 2022-12-19 Idoia Eizaguirre-Peral , Lander Segurola-Gil , Francesco Zola

Deep neural networks (DNNs) are vulnerable to backdoor attack, which does not affect the network's performance on clean data but would manipulate the network behavior once a trigger pattern is added. Existing defense methods have greatly…

Machine Learning · Computer Science 2025-04-08 Min Liu , Alberto Sangiovanni-Vincentelli , Xiangyu Yue

Artificial synthesis of DNA molecules is an essential part of the study of biological mechanisms. The design of a synthetic DNA molecule usually involves many objectives. One of the important objectives is to eliminate short sequence…

Biomolecules · Quantitative Biology 2021-08-13 Zehavit Leibovich , Ilan Gronau

Living in the age of the digital media explosion, the amount of data that is being stored increases dramatically. However, even if existing storage systems suggest efficiency in capacity, they are lacking in durability. Hard disks, flash,…

Image and Video Processing · Electrical Eng. & Systems 2019-04-08 Melpomeni Dimopoulou , Marc Antonini , Pascal Barbry , Raja Appuswamy

Malware attacks have a significant negative impact on organizations of varied scales in the field of cybersecurity. Recently, malware researchers have increasingly turned to machine learning techniques to combat sophisticated obfuscation…

Machine Learning · Computer Science 2026-04-27 Tiffany Bao , Kylie Trousil , Quang Duy Tran , Fabio Di Troia , Younghee Park

In the realm of IoT/CPS systems connected over mobile networks, traditional intrusion detection methods analyze network traffic across multiple devices using anomaly detection techniques to flag potential security threats. However, these…

Cryptography and Security · Computer Science 2024-10-07 Anantaa Kotal , Brandon Luton , Anupam Joshi

The DNA cryptography is a new and very promising direction in cryptography research. DNA can be used in cryptography for storing and transmitting the information, as well as for computation. Although in its primitive stage, DNA cryptography…

Cryptography and Security · Computer Science 2012-03-07 Kang Ning

DNA, encoding genetic instructions for almost all living organisms, fuels groundbreaking advances in genomics and synthetic biology. Recently, DNA Foundation Models have achieved success in designing synthetic functional DNA sequences, even…

Cryptography and Security · Computer Science 2025-06-02 Zaixi Zhang , Zhenghong Zhou , Ruofan Jin , Le Cong , Mengdi Wang

We analyze security aspects of the SecureDNA system regarding its system design, engineering, and implementation. This system enables DNA synthesizers to screen order requests against a database of hazards. By applying novel cryptography,…

Cryptography and Security · Computer Science 2025-12-11 Alan T. Sherman , Jeremy J. Romanik Romano , Edward Zieglar , Enis Golaszewski , Jonathan D. Fuchs , William E. Byrd

Synthetic Data Generation (SDG) can be used to facilitate privacy-preserving data sharing. However, most existing research focuses on privacy attacks where the adversary is the recipient of the released synthetic data and attempts to infer…

Cryptography and Security · Computer Science 2026-05-21 Qinyi Liu , Dong Liu , Sam Urmian , Mohammad Khalil , Pedro P. Vergara Barrios

When machine learning training is outsourced to third parties, $backdoor$ $attacks$ become practical as the third party who trains the model may act maliciously to inject hidden behaviors into the otherwise accurate model. Until now, the…

Cryptography and Security · Computer Science 2022-11-16 Sanghyun Hong , Nicholas Carlini , Alexey Kurakin

The availability of genomic data is essential to progress in biomedical research, personalized medicine, etc. However, its extreme sensitivity makes it problematic, if not outright impossible, to publish or share it. As a result, several…

Genomics · Quantitative Biology 2022-01-19 Bristena Oprisanu , Georgi Ganev , Emiliano De Cristofaro
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