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We consider a population of haploid individuals reproducing sexually, i.e. for which the genome of each individual is a random mixture of the genome of its two parents. We assume that initially one individual carries a mutation at one…

Probability · Mathematics 2022-10-06 Camille Coron , Yves Le Jan

This paper deals with simultaneously fast and in-place algorithms for formulae where the result has to be linearly accumulated: some of the output variables are also input variables, linked by a linear dependency. Fundamental examples…

Symbolic Computation · Computer Science 2024-07-02 Jean-Guillaume Dumas , Bruno Grenet

We introduce a mathematical model that combines the concepts of complex contagion with payoff-biased imitation, to describe how social behaviors spread through a population. Traditional models of social learning by imitation are based on…

Physics and Society · Physics 2025-01-13 Hiroaki Chiba-Okabe , Joshua B. Plotkin

Natural selection explains how life has evolved over millions of years from more primitive forms. The speed at which this happens, however, has sometimes defied formal explanations when based on random (uniformly distributed) mutations.…

Neural and Evolutionary Computing · Computer Science 2018-06-22 Santiago Hernández-Orozco , Narsis A. Kiani , Hector Zenil

We study a stochastic model based on a modified fragmentation of a finite interval. The mechanism consists in cutting the interval at a random location and substituting a unique fragment on the right of the cut to regenerate and preserve…

Statistical Mechanics · Physics 2018-04-25 Jean-Yves Fortin

The rotation induced inhomogeneous problem is non-trivial and inevitable. In this paper a generic framework is developed to investigate the inhomogeneous condensate in a system of fermions under the presence of rotation. It is a…

Nuclear Theory · Physics 2019-09-11 Lingxiao Wang , Yin Jiang , Lianyi He , Pengfei Zhuang

We study the emergency of mutual cooperation in evolutionary prisoner's dilemma games when the players are located on a square lattice. The players can choose one of the three strategies: cooperation (C), defection (D) or "tit for tat" (T),…

Statistical Mechanics · Physics 2015-06-24 Gyorgy Szabo , Tibor Antal , Peter Szabo , Michel Droz

We consider the evolution of populations under the joint action of mutation and differential reproduction, or selection. The population is modelled as a finite-type Markov branching process in continuous time, and the associated…

Populations and Evolution · Quantitative Biology 2009-02-23 Ellen Baake , Hans-Otto Georgii

Templated copying is the central operation by which biology produces complex molecules. Cells copy sequence information from DNA to RNA and on into proteins, which are the molecules responsible for the function and regulation of cellular…

Biological Physics · Physics 2021-04-13 Jenny Poulton

Modern biomedicine is challenged to predict the effects of genetic variation. Systematic functional assays of point mutants of proteins have provided valuable empirical information, but vast regions of sequence space remain unexplored.…

Biomolecules · Quantitative Biology 2017-01-18 Thomas A. Hopf , John B. Ingraham , Frank J. Poelwijk , Michael Springer , Chris Sander , Debora S. Marks

Discrete dynamical systems defined by the iteration of a polynomial map of the unit simplex to itself appear in the context of population genetic systems evolving under mutation, recombination and weak selection. Although exceptional…

Dynamical Systems · Mathematics 2013-07-15 Sergio Lukic

Motivated by mutation processes occurring in in-vivo DNA-storage applications, a channel that mutates stored strings by duplicating substrings as well as substituting symbols is studied. Two models of such a channel are considered: one in…

Information Theory · Computer Science 2020-07-01 Yuanyuan Tang , Yonatan Yehezkeally , Moshe Schwartz , Farzad Farnoud

The adaptation process of a species to a new environment is a significant area of study in biology. As part of natural selection, adaptation is a mutation process which improves survival skills and reproductive functions of species. Here,…

Populations and Evolution · Quantitative Biology 2017-10-27 Maria Kleshnina , Jerzy A. Filar , Vladimir Ejov , Jody C. McKerral

We consider a population of N individuals, whose dynamics through time is represented by a biparental Moran model with two types: an advantaged type and a disadvantaged type. The advantage is due to a mutation, transmitted in a Mendelian…

Probability · Mathematics 2024-05-15 Camille Coron , Yves Le Jan

The existence of complex (multiple-step) genetic adaptations that are "irreducible" (i.e., all partial combinations are less fit than the original genotype) is one of the longest standing problems in evolutionary biology. In standard…

Populations and Evolution · Quantitative Biology 2014-10-17 Meredith V. Trotter , Daniel B. Weissman , Grant I. Peterson , Kayla M. Peck , Joanna Masel

Granular convergence is a property of a granular pack as it is repeatedly sheared in a cyclic, quasistatic fashion, as the packing configuration changes via discrete events. Under suitable conditions the set of microscopic configurations…

Soft Condensed Matter · Physics 2023-08-25 Anna Movsheva , Thomas A. Witten

We investigate the effect of spatial range expansions on the evolution of fitness when beneficial and deleterious mutations co-segregate. We perform individual-based simulations of a uniform linear habitat and complement them with…

Populations and Evolution · Quantitative Biology 2013-06-10 Stephan Peischl , Isabelle Dupanloup , Mark Kirkpatrick , Laurent Excoffier

The Moran process is a classic stochastic process that models the rise and takeover of novel traits in network-structured populations. In biological terms, a set of mutants, each with fitness $m\in(0,\infty)$ invade a population of…

Data Structures and Algorithms · Computer Science 2024-05-14 Petros Petsinis , Andreas Pavlogiannis , Josef Tkadlec , Panagiotis Karras

Immunological systems have been an abundant inspiration to contemporary computer scientists. Problem solving strategies, stemming from known immune system phenomena, have been successfully applied to challenging problems of modern computing…

Cell Behavior · Quantitative Biology 2017-05-24 Alexandre de Castro , Carlos Frederico Fronza , Domingos Alves

Surprise-based learning allows agents to rapidly adapt to non-stationary stochastic environments characterized by sudden changes. We show that exact Bayesian inference in a hierarchical model gives rise to a surprise-modulated trade-off…

Machine Learning · Statistics 2020-09-25 Vasiliki Liakoni , Alireza Modirshanechi , Wulfram Gerstner , Johanni Brea