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Many biological populations exhibit diversity in their strategy for survival and reproduction in a given environment, and microbes are an example. We explore the fate of different strategies under sustained environmental change by…

Populations and Evolution · Quantitative Biology 2025-09-24 Ruixi Huang , David Waxman

The number of fixed mutations accumulated in an evolving population often displays a variance that is significantly larger than the mean (the overdispersed molecular clock). By examining a generic evolutionary process on a neutral network…

Populations and Evolution · Quantitative Biology 2009-11-13 Alpan Raval

Inspired by Fisher's geometric approach to study beneficial mutations, we analyse probabilities of beneficial mutation and crossover recombination of strings in a general Hamming space with arbitrary finite alphabet. Mutations and…

Populations and Evolution · Quantitative Biology 2025-06-18 Roman V. Belavkin

The aim of our work is to study the effect of geometry variation on nucleation times and to address its role in the context of eukaryotic chemotaxis (i.e. the process which allows cells to identify and follow a gradient of chemical…

Statistical Mechanics · Physics 2010-02-10 Carla Bosia , Michele Caselle , Davide Corá

The pattern of radiation energy deposition in substances at the microscopic level of lattice, molecule size, or the cell's nucleus is not uniform. The energy of radiation is transferred to the substance medium in the form of discrete,…

Medical Physics · Physics 2022-10-14 Elsayed K. Elmaghraby , Mohamed Bahaaeldin-Afifi

Time-resolved analysis of periodically excited luminescence decays by the phasor method in the presence of time-gating or binning is revisited. Analytical expressions for discrete configurations of square gates are derived and the locus of…

Quantitative Methods · Quantitative Biology 2023-07-19 Xavier Michalet

Evolutionary game dynamics is one of the most fruitful frameworks for studying evolution in different disciplines, from Biology to Economics. Within this context, the approach of choice for many researchers is the so-called replicator…

Populations and Evolution · Quantitative Biology 2009-11-14 Carlos P. Roca , José A. Cuesta , Angel Sánchez

Cancer cell mutations occur when cells undergo multiple cell divisions, and these mutations can be spontaneous or environmentally-induced. The mechanisms that promote and sustain these mutations are still not fully understood. This study…

Dynamical Systems · Mathematics 2021-10-27 Maher Alwuthaynani , Raluca Eftimie , Dumitru Trucu

We introduce a use of the \(M\)-cover (or \(M\)-layer) transform for machine learning. The method replicates a model \(M\) times, but instead of coupling the copies through parameter averaging or an explicit attractive force, as in…

Machine Learning · Computer Science 2026-05-12 Shuhei Kashiwamura , Timothee Leleu

The outcomes of evolution are determined by which mutations occur and fix. In rapidly adapting microbial populations, this process is particularly hard to predict because lineages with different beneficial mutations often spread…

Populations and Evolution · Quantitative Biology 2014-02-17 Evgeni M. Frenkel , Benjamin H. Good , Michael M. Desai

The inevitable existence of static internal imperfections and residual interactions in some quantum computer architectures result in internal decoherence, dissipation, and destructive unitary shifts of active algorithms. By exact numerical…

Quantum Physics · Physics 2009-11-13 Murat Cetinbas , Joshua Wilkie

In the framework of the crystal basis model of the genetic code, where each codon is assigned to an irreducible representation of $U_{q \to 0}(sl(2) \oplus sl(2))$, single base mutation matrices are introduced. The strength of the mutation…

Mathematical Physics · Physics 2007-05-23 Antonino Sciarrino

We study the fraction $f$ of nucleotides involved in the formation of a cactus--like secondary structure of random heteropolymer RNA--like molecules. In the low--temperature limit we study this fraction as a function of the number $c$ of…

Genomics · Quantitative Biology 2013-05-30 O. V. Valba , M. V. Tamm , S. K. Nechaev

When involution affects individuals, their efforts do not augment resources but merely compete for limited resources. From entrance exams to company overtime, such efforts lead to unnecessary costs, undermining group welfare. Meanwhile, the…

Statistical Mechanics · Physics 2023-12-13 Chaochao Huang , Chaoqian Wang

Modified quark fragmentation functions in deeply inelastic $eA$ collisions and their QCD evolution equations are derived for the first time in the framework of multiple parton scattering. Induced radiation gives rise to additional terms in…

High Energy Physics - Phenomenology · Physics 2008-11-26 Xiaofeng Guo , Xin-Nian Wang

Any process in which competing solutions replicate with errors and numbers of their copies depend on their respective fitnesses is the evolutionary optimization process. As during carcinogenesis mutated genomes replicate according to their…

Populations and Evolution · Quantitative Biology 2009-12-15 B. Brutovsky , D. Horvath

A matrix network is a family of matrices, with relatedness modeled by a weighted graph. We consider the task of completing a partially observed matrix network. We assume a novel sampling scheme where a fraction of matrices might be…

Machine Learning · Computer Science 2018-06-11 Qingyun Sun , Mengyuan Yan David Donoho , Stephen Boyd

We characterise mutations between fake weighted projective spaces, and give explicit formulas for how the weights and multiplicity change under mutation. In particular, we prove that multiplicity-preserving mutations between fake weighted…

Algebraic Geometry · Mathematics 2022-09-22 Tom Coates , Samuel Gonshaw , Alexander Kasprzyk , Navid Nabijou

Highly nonlinear behavior of a system of discrete sites on a lattice is observed when a specific feedback loop is introduced into models employing coupled map lattices, quantum cellular automata, or the real-valued analogues of the latter.…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Siegfried Fussy , Gerhard Groessing , Herbert Schwabl

Recent empirical studies have identified fixed point iteration phenomena in deep neural networks, where the hidden state tends to stabilize after several layers, showing minimal change in subsequent layers. This observation has spurred the…

Machine Learning · Computer Science 2024-10-16 Yekun Ke , Xiaoyu Li , Yingyu Liang , Zhenmei Shi , Zhao Song
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