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Last years have been characterized by an upsurge of opaque automatic decision support systems, such as Deep Neural Networks (DNNs). Although they have great generalization and prediction skills, their functioning does not allow obtaining…

Artificial intelligence has become pervasive across disciplines and fields, and biomedical image and signal processing is no exception. The growing and widespread interest on the topic has triggered a vast research activity that is…

Machine Learning · Computer Science 2022-07-12 Guang Yang , Arvind Rao , Christine Fernandez-Maloigne , Vince Calhoun , Gloria Menegaz

With the broader and highly successful usage of machine learning in industry and the sciences, there has been a growing demand for Explainable AI. Interpretability and explanation methods for gaining a better understanding about the problem…

Machine Learning · Computer Science 2021-02-26 Wojciech Samek , Grégoire Montavon , Sebastian Lapuschkin , Christopher J. Anders , Klaus-Robert Müller

Artificial intelligence (AI) continues to transform data analysis in many domains. Progress in each domain is driven by a growing body of annotated data, increased computational resources, and technological innovations. In medicine, the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Ahmad Chaddad , Qizong lu , Jiali Li , Yousef Katib , Reem Kateb , Camel Tanougast , Ahmed Bouridane , Ahmed Abdulkadir

With the increasing availability of structured and unstructured data and the swift progress of analytical techniques, Artificial Intelligence (AI) is bringing a revolution to the healthcare industry. With the increasingly indispensable role…

Machine Learning · Computer Science 2020-11-09 Devam Dave , Het Naik , Smiti Singhal , Pankesh Patel

Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

In recent years, AI systems in the medical domain have advanced significantly. However, despite outperforming humans, they are rarely used in practice since it is often not clear how they make their decisions. Optimal explanation and…

Human-Computer Interaction · Computer Science 2026-05-06 Julia Wagner , Tim Schlippe

Artificial Intelligence (AI) is rapidly integrating into various aspects of our daily lives, influencing decision-making processes in areas such as targeted advertising and matchmaking algorithms. As AI systems become increasingly…

Artificial Intelligence · Computer Science 2025-03-11 Md. Tanzib Hosain , Mehedi Hasan Anik , Sadman Rafi , Rana Tabassum , Khaleque Insia , Md. Mehrab Siddiky

Advances in computing power, deep learning architectures, and expert labelled datasets have spurred the development of medical imaging artificial intelligence systems that rival clinical experts in a variety of scenarios. The National…

Image and Video Processing · Electrical Eng. & Systems 2021-11-18 Rohan Shad , John P. Cunningham , Euan A. Ashley , Curtis P. Langlotz , William Hiesinger

As artificial intelligence (AI) becomes increasingly embedded in healthcare delivery, this chapter explores the critical aspects of developing reliable and ethical Clinical Decision Support Systems (CDSS). Beginning with the fundamental…

Artificial Intelligence · Computer Science 2025-02-18 Muhammet Alkan , Idris Zakariyya , Samuel Leighton , Kaushik Bhargav Sivangi , Christos Anagnostopoulos , Fani Deligianni

Explanations for artificial intelligence (AI) systems are intended to support the people who are impacted by AI systems in high-stakes decision-making environments, such as doctors, patients, teachers, students, housing applicants, and many…

Human-Computer Interaction · Computer Science 2025-04-16 Gennie Mansi , Naveena Karusala , Mark Riedl

Digital pathology is not only one of the most promising fields of diagnostic medicine, but at the same time a hot topic for fundamental research. Digital pathology is not just the transfer of histopathological slides into digital…

Artificial Intelligence · Computer Science 2017-12-20 Andreas Holzinger , Bernd Malle , Peter Kieseberg , Peter M. Roth , Heimo Müller , Robert Reihs , Kurt Zatloukal

The past years have seen a considerable increase in cancer cases. However, a cancer diagnosis is often complex and depends on the types of images provided for analysis. It requires highly skilled practitioners but is often time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2022-10-24 Solene Bechelli

Artificial intelligence (AI) generally and machine learning (ML) specifically demonstrate impressive practical success in many different application domains, e.g. in autonomous driving, speech recognition, or recommender systems. Deep…

Artificial Intelligence · Computer Science 2018-01-02 Andreas Holzinger , Chris Biemann , Constantinos S. Pattichis , Douglas B. Kell

Artificial intelligence (AI) algorithms using deep learning have advanced the classification of skin disease images; however these algorithms have been mostly applied "in silico" and not validated clinically. Most dermatology AI algorithms…

Computer Vision and Pattern Recognition · Computer Science 2021-05-24 Roxana Daneshjou , Carrie Kovarik , Justin M Ko

There has recently been a surge of work in explanatory artificial intelligence (XAI). This research area tackles the important problem that complex machines and algorithms often cannot provide insights into their behavior and thought…

Artificial Intelligence · Computer Science 2019-02-05 Leilani H. Gilpin , David Bau , Ben Z. Yuan , Ayesha Bajwa , Michael Specter , Lalana Kagal

Artificial Intelligence (AI) is poised to transform healthcare delivery through revolutionary advances in clinical decision support and diagnostic capabilities. While human expertise remains foundational to medical practice, AI-powered…

We are witnessing the emergence of an AI economy and society where AI technologies are increasingly impacting health care, business, transportation and many aspects of everyday life. Many successes have been reported where AI systems even…

Machine Learning · Computer Science 2022-12-27 D. Petkovic

In medical imaging, particularly in early disease detection and prognosis tasks, discerning the rationale behind an AI model's predictions is crucial for evaluating the reliability of its decisions. Conventional explanation methods face…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Yingying Fang , Zihao Jin , Xiaodan Xing , Simon Walsh , Guang Yang

The recent enthusiasm for artificial intelligence (AI) is due principally to advances in deep learning. Deep learning methods are remarkably accurate, but also opaque, which limits their potential use in safety-critical applications. To…