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We propose a solution to the weight transport problem, which questions the biological plausibility of the backpropagation algorithm. We derive our method based upon a theoretical analysis of the (approximate) dynamics of leaky…

Neurons and Cognition · Quantitative Biology 2021-08-12 Nasir Ahmad , Luca Ambrogioni , Marcel A. J. van Gerven

The backpropagation algorithm has experienced remarkable success in training large-scale artificial neural networks; however, its biological plausibility has been strongly criticized, and it remains an open question whether the brain…

Neural and Evolutionary Computing · Computer Science 2026-03-27 Bariscan Bozkurt , Cengiz Pehlevan , Alper T Erdogan

Training deep neural networks with the error backpropagation algorithm is considered implausible from a biological perspective. Numerous recent publications suggest elaborate models for biologically plausible variants of deep learning,…

Neural and Evolutionary Computing · Computer Science 2019-07-16 Bernd Illing , Wulfram Gerstner , Johanni Brea

Artificial neural networks, one of the most successful approaches to supervised learning, were originally inspired by their biological counterparts. However, the most successful learning algorithm for artificial neural networks,…

Machine Learning · Computer Science 2020-06-18 Matilde Tristany Farinha , Sérgio Pequito , Pedro A. Santos , Mário A. T. Figueiredo

Neuroscientists have long criticised deep learning algorithms as incompatible with current knowledge of neurobiology. We explore more biologically plausible versions of deep representation learning, focusing here mostly on unsupervised…

Machine Learning · Computer Science 2016-08-10 Yoshua Bengio , Dong-Hyun Lee , Jorg Bornschein , Thomas Mesnard , Zhouhan Lin

The way how recurrently connected networks of spiking neurons in the brain acquire powerful information processing capabilities through learning has remained a mystery. This lack of understanding is linked to a lack of learning algorithms…

Neural and Evolutionary Computing · Computer Science 2019-02-22 Guillaume Bellec , Franz Scherr , Elias Hajek , Darjan Salaj , Robert Legenstein , Wolfgang Maass

The backpropagation (BP) algorithm is often thought to be biologically implausible in the brain. One of the main reasons is that BP requires symmetric weight matrices in the feedforward and feedback pathways. To address this "weight…

Machine Learning · Computer Science 2018-12-24 Will Xiao , Honglin Chen , Qianli Liao , Tomaso Poggio

Understanding how the brain learns may be informed by studying biologically plausible learning rules. These rules, often approximating gradient descent learning to respect biological constraints such as locality, must meet two critical…

Neural and Evolutionary Computing · Computer Science 2025-06-10 Yuhan Helena Liu , Guangyu Robert Yang , Christopher J. Cueva

Humans excel at continually acquiring, consolidating, and retaining information from an ever-changing environment, whereas artificial neural networks (ANNs) exhibit catastrophic forgetting. There are considerable differences in the…

Neural and Evolutionary Computing · Computer Science 2023-04-17 Fahad Sarfraz , Elahe Arani , Bahram Zonooz

Spiking neural networks (SNNs) are a viable alternative to conventional artificial neural networks when resource efficiency and computational complexity are of importance. A major advantage of SNNs is their binary information transfer…

Neural and Evolutionary Computing · Computer Science 2023-10-18 Daniel Gerlinghoff , Tao Luo , Rick Siow Mong Goh , Weng-Fai Wong

Despite remarkable technological advances, AI systems may still benefit from biological principles, such as recurrent connectivity and energy-efficient mechanisms. Drawing inspiration from the brain, we present a biologically plausible…

The problem of training spiking neural networks (SNNs) is a necessary precondition to understanding computations within the brain, a field still in its infancy. Previous work has shown that supervised learning in multi-layer SNNs enables…

Neural and Evolutionary Computing · Computer Science 2018-03-12 Amirhossein Tavanaei , Anthony S. Maida

Bio-inspired neural networks are attractive for their adversarial robustness, energy frugality, and closer alignment with cortical physiology, yet they often lag behind back-propagation (BP) based models in accuracy and ability to scale. We…

Neural and Evolutionary Computing · Computer Science 2025-07-21 Imane Hamzaoui , Riyadh Baghdadi

Hebbian plasticity is a powerful principle that allows biological brains to learn from their lifetime experience. By contrast, artificial neural networks trained with backpropagation generally have fixed connection weights that do not…

Neural and Evolutionary Computing · Computer Science 2016-10-20 Thomas Miconi

In a physical neural system, where storage and processing are intimately intertwined, the rules for adjusting the synaptic weights can only depend on variables that are available locally, such as the activity of the pre- and post-synaptic…

Machine Learning · Computer Science 2016-10-25 Pierre Baldi , Peter Sadowski

We propose a novel local learning rule for spiking neural networks in which spike propagation times undergo activity-dependent plasticity. Our plasticity rule aligns pre-synaptic spike times to produce a stronger and more rapid response.…

Neural and Evolutionary Computing · Computer Science 2022-11-16 Jørgen Jensen Farner , Ola Huse Ramstad , Stefano Nichele , Kristine Heiney

The plasticity of the conduction delay between neurons plays a fundamental role in learning. However, the exact underlying mechanisms in the brain for this modulation is still an open problem. Understanding the precise adjustment of…

Neural and Evolutionary Computing · Computer Science 2020-11-19 Alireza Nadafian , Mohammad Ganjtabesh

Spiking neural networks (SNNs) possess energy-efficient potential due to event-based computation. However, supervised training of SNNs remains a challenge as spike activities are non-differentiable. Previous SNNs training methods can be…

Neural and Evolutionary Computing · Computer Science 2019-10-08 Yunzhe Hao , Xuhui Huang , Meng Dong , Bo Xu

Artificial Neural Network (ANN)-based inference on battery-powered devices can be made more energy-efficient by restricting the synaptic weights to be binary, hence eliminating the need to perform multiplications. An alternative, emerging,…

Machine Learning · Computer Science 2020-12-16 Hyeryung Jang , Nicolas Skatchkovsky , Osvaldo Simeone

It is widely believed that the backpropagation algorithm is essential for learning good feature detectors in early layers of artificial neural networks, so that these detectors are useful for the task performed by the higher layers of that…

Machine Learning · Computer Science 2019-08-30 Dmitry Krotov , John Hopfield