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Testing is a crucial control mechanism in the beginning phase of an epidemic when the vaccines are not yet available. It enables the public health authority to detect and isolate the infected cases from the population, thereby limiting the…

We find UK 'local lockdowns' of cities and small regions, focused on limiting how many people a household can interact with and in what settings, are effective in turning the tide on rising positive COVID-19 cases. Yet, by focusing on…

General Economics · Economics 2021-02-05 John Gathergood , Benedict Guttman-Kenney

If we can lower the number of people needed to vaccinate for a community to be immune against contagious diseases, we can save resources and life. A key to reach such a lower threshold of immunization is to find and vaccinate people who,…

Populations and Evolution · Quantitative Biology 2012-10-10 Sungmin Lee , Luis E. C. Rocha , Fredrik Liljeros , Petter Holme

The COVID-19 crisis highlighted the importance of non-medical interventions, such as testing and isolation of infected individuals, in the control of epidemics. Here, we show how to minimize testing needs while maintaining the number of…

Systems and Control · Electrical Eng. & Systems 2024-07-04 D. Acemoglu , A. Fallah , A. Giometto , D. Huttenlocher , A. Ozdaglar , F. Parise , S. Pattathil

This work focuses on optimal controls of a class of stochastic SIS epidemic models under regime switching. By assuming that a decision maker can either influence the infectivity period or isolate infected individuals, our aim is to minimize…

Optimization and Control · Mathematics 2021-01-12 Ky Tran , George Yin

We point out that a simple and generic strategy to lower the risk for extinction consists in the developing a dormant stage in which the organism is unable to multiply but may die. The dormant organism is protected against the poisonous…

Populations and Evolution · Quantitative Biology 2010-02-25 Tomas Alarcon , Henrik Jeldtoft Jensen

How much and when should we limit economic and social activity to ensure that the health-care system is not overwhelmed during an epidemic? We study a setting where ICU resources are constrained while suppression is costly (e.g., limiting…

Theoretical Economics · Economics 2020-05-05 Laurent Miclo , Daniel Spiro , Jörgen Weibull

Connectivity - or the lack thereof - is crucial for the function of many man-made systems, from financial and economic networks over epidemic spreading in social networks to technical infrastructure. Often, connections are deliberately…

Disordered Systems and Neural Networks · Physics 2017-12-13 Malte Schröder , Nuno A. M. Araújo , Didier Sornette , Jan Nagler

We study the critical effect of an intermittent social distancing strategy on the propagation of epidemics in adaptive complex networks. We characterize the effect of our strategy in the framework of the susceptible-infected-recovered…

Physics and Society · Physics 2012-04-02 L. D. Valdez , P. A. Macri , L. A. Braunstein

We use analytical methods to investigate a continuous vaccination strategy effects on the infectious disease dynamics in a closed population and a demographically open population. The methodology and key assumptions are based on Breda et al…

Populations and Evolution · Quantitative Biology 2020-09-24 Aubain Nzokem , Neal Madras

This paper presents a study on a compartmental epidemic model for COVID-19, examining the stability of its equilibrium points upon the introduction of vaccination as a strategy to mitigate the spread of the disease. Initially, the SIQR…

Numerical Analysis · Mathematics 2024-05-29 Leonardo R. S. Rodrigues , Felipe Gabrielli

The decision of whether or not to vaccinate is a complex one. It involves the contribution both to a social good -- herd immunity -- and to one's own well being. It is informed by social influence, personal experience, education, and mass…

Populations and Evolution · Quantitative Biology 2022-02-15 Soya Miyoshi , Marko Jusup , Petter Holme

Given multiple new COVID-19 variants are continuously emerging, non-pharmaceutical interventions are still primary control strategies to curb the further spread of coronavirus. However, implementing strict interventions over extended…

Populations and Evolution · Quantitative Biology 2022-03-01 Xiao Zhou , Xiaohu Zhang , Paolo Santi , Carlo Ratti

During epidemic outbreaks, information dissemination enhances individual protection, while social institutions influence the transmission through measures like government interventions, media campaigns, and hospital resource allocation.…

Physics and Society · Physics 2025-06-03 Mengshou Wang , Liangrong Peng , Baoguo Jia , Liu Hong

This study presents a seasonally forced cholera model that incorporates imperfect vaccination as a control strategy. The model captures the temporal dynamics of susceptible, vaccinated, infected, and recovered individuals, as well as the…

Populations and Evolution · Quantitative Biology 2025-07-15 Eric Herrison Gyamfi

The current COVID-19 pandemic and subsequent lockdowns have highlighted the close and delicate relationship between a country's public health and economic health. Macroeconomic models that use preexisting epidemic models to calculate the…

Physics and Society · Physics 2020-07-01 Erhan Bayraktar , Asaf Cohen , April Nellis

Contact tracing has been extensively studied from different perspectives in recent years. However, there is no clear indication of why this intervention has proven effective in some epidemics (SARS) and mostly ineffective in some others…

Social and Information Networks · Computer Science 2021-03-01 Quyu Kong , Manuel Garcia-Herranz , Ivan Dotu , Manuel Cebrian

Containing an epidemic at its origin is the most desirable mitigation. Epidemics have often originated in rural areas, with rural communities among the first affected. Disease dynamics in rural regions have received limited attention, and…

With a two-layer contact-dispersion model and data in China, we analyze the cost-effectiveness of three types of antiepidemic measures for COVID-19: regular epidemiological control, local social interaction control, and inter-city travel…

In this article, we construct an age-structured model for COVID-19 with vaccination and analyze it from multiple perspectives. We derive the unique disease-free equilibrium point and the basic reproduction number $ \mathscr{R}_0 $, then we…

Populations and Evolution · Quantitative Biology 2024-07-09 Ruiyang Zhou , Fengying Wei