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We show that de-focused single particle images recorded using a cryo-electron microscope (cryoEM) system may be processed like a Fresnel zone in-line hologram to obtain physically meaningful quantitative phase maps associated with…

Image and Video Processing · Electrical Eng. & Systems 2021-11-24 Apoorv Pant , Manidipa Banerjee , Kedar Khare

The CryoEM single particle imaging method has recently received broad attention in the field of structural biology for determining the structures of biological molecules. The structures can be resolved to near-atomic resolutions after…

Biomolecules · Quantitative Biology 2017-12-27 Yihua Wang , Daqi Yu , Qi Ouyang , Haiguang Liu

Image super-resolution (SR) is one of the vital image processing methods that improve the resolution of an image in the field of computer vision. In the last two decades, significant progress has been made in the field of super-resolution,…

Computer Vision and Pattern Recognition · Computer Science 2022-09-07 Syed Muhammad Arsalan Bashir , Yi Wang , Mahrukh Khan , Yilong Niu

Programmable self-assembly has recently enabled the creation of complex structures through precise control of the interparticle interactions and the particle geometries. Targeting ever more structurally complex, dynamic, and functional…

Absorption imaging is the most common probing technique in experiments with ultracold atoms. The standard procedure involves the division of two frames acquired at successive exposures, one with the atomic absorption signal and one without.…

Quantum Gases · Physics 2020-07-08 Gal Ness , Anastasiya Vainbaum , Constantine Shkedrov , Yanay Florshaim , Yoav Sagi

Image registration is a fundamental task for medical imaging. Resampling of the intensity values is required during registration and better spatial resolution with finer and sharper structures can improve the resampling performance and…

Image and Video Processing · Electrical Eng. & Systems 2022-01-03 Kaicong Sun , Sven Simon

Recently, convolutional neural networks (CNN) have been successfully applied to many remote sensing problems. However, deep learning techniques for multi-image super-resolution from multitemporal unregistered imagery have received little…

Image and Video Processing · Electrical Eng. & Systems 2020-01-16 Andrea Bordone Molini , Diego Valsesia , Giulia Fracastoro , Enrico Magli

Understanding the structure of supramolecular complexes provides insight into their functional capabilities and how they can be modulated in the context of disease. Super-resolution microscopy (SRM) excels in performing this task by…

Quantitative Methods · Quantitative Biology 2023-08-09 Afonso Mendes , Hannah S. Heil , Simao Coelho , Christophe Leterrier , Ricardo Henriques

Cryo-electron microscopy (cryo-EM) has emerged as a powerful technique for determining the three-dimensional structures of biological molecules at near-atomic resolution. However, reconstructing helical assemblies presents unique challenges…

Quantitative Methods · Quantitative Biology 2026-03-16 Guy Shapira , Yoel Shkolnisky

Recent methods for single image super-resolution (SISR) have demonstrated outstanding performance in generating high-resolution (HR) images from low-resolution (LR) images. However, most of these methods show their superiority using…

Computer Vision and Pattern Recognition · Computer Science 2022-08-25 Jun-Sang Yoo , Dong-Wook Kim , Yucheng Lu , Seung-Won Jung

The central problem in cryo-electron microscopy (cryo-EM) is to recover the 3D structure from noisy 2D projection images which requires estimating the missing projection angles (poses). Recent methods attempted to solve the 3D…

Computer Vision and Pattern Recognition · Computer Science 2023-02-15 Lin Yao , Ruihan Xu , Zhifeng Gao , Guolin Ke , Yuhang Wang

This paper presents deep unfolding neural networks to handle inverse problems in photothermal radiometry enabling super resolution (SR) imaging. Photothermal imaging is a well-known technique in active thermography for nondestructive…

Computer Vision and Pattern Recognition · Computer Science 2021-04-22 Samim Ahmadi , Linh Kästner , Jan Christian Hauffen , Peter Jung , Mathias Ziegler

Scanning Electron Microscopes (SEMs) are widely renowned for their ability to analyze the surface structures of microscopic objects, offering the capability to capture highly detailed, yet only grayscale, images. To create more expressive…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Takuma Nishimura , Andreea Dogaru , Martin Oeggerli , Bernhard Egger

Cryo-electron tomography (cryo-ET) is an emerging technology for the 3D visualization of structural organizations and interactions of subcellular components at near-native state and sub-molecular resolution. Tomograms captured by cryo-ET…

Quantitative Methods · Quantitative Biology 2020-11-02 Xiangrui Zeng , Min Xu

A common task in cryo-electron microscopy (cryo-EM) data processing is to compare three-dimensional density maps of macromolecules. In this paper, we propose an algorithm for aligning three-dimensional density maps that exploits common…

Image and Video Processing · Electrical Eng. & Systems 2023-02-27 Yael Harpaz , Yoel Shkolnisky

Image Super Resolution (SR) finds applications in areas where images need to be closely inspected by the observer to extract enhanced information. One such focused application is an offline forensic analysis of surveillance feeds. Due to…

Computer Vision and Pattern Recognition · Computer Science 2021-07-12 Muhammad Ali Farooq , Ammar Ali Khan , Ansar Ahmad , Rana Hammad Raza

Deep learning-based super-resolution models have the potential to revolutionize biomedical imaging and diagnoses by effectively tackling various challenges associated with early detection, personalized medicine, and clinical automation.…

Medical Physics · Physics 2023-06-27 Yuanzheng Ma , Xinyue Wang , Benqi Zhao , Ying Xiao , Shijie Deng , Jian Song , Xun Guan

Super-resolution is the process of obtaining a high-resolution image from one or more low-resolution images. Single image super-resolution (SISR) and multi-frame super-resolution (MFSR) methods have been evolved almost independently for…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Mohammad Mahdi Afrasiabi , Reshad Hosseini , Aliazam Abbasfar

Cryo-electron tomography (cryo-ET) enables 3D visualization of cellular structures. Accurate reconstruction of high-resolution volumes is complicated by the very low signal-to-noise ratio and a restricted range of sample tilts. Recent…

Image and Video Processing · Electrical Eng. & Systems 2026-03-03 Vinith Kishore , Valentin Debarnot , AmirEhsan Khorashadizadeh , Ricardo D. Righetto , Benjamin D. Engel , Ivan Dokmanić

We introduce DiffFit, a differentiable algorithm for fitting protein atomistic structures into an experimental reconstructed Cryo-Electron Microscopy (cryo-EM) volume map. In structural biology, this process is necessary to…

Quantitative Methods · Quantitative Biology 2025-01-09 Deng Luo , Zainab Alsuwaykit , Dawar Khan , Ondřej Strnad , Tobias Isenberg , Ivan Viola