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Antibiotic resistance constitutes a major health threat. Predicting bacterial causes of infections is key to reducing antibiotic misuse, a leading driver of antibiotic resistance. We train a machine learning algorithm on administrative and…

General Economics · Economics 2019-06-10 Michael Allan Ribers , Hannes Ullrich

AI systems increasingly support human decision-making. In many cases, despite the algorithm's superior performance, the final decision remains in human hands. For example, an AI may assist doctors in determining which diagnostic tests to…

Artificial Intelligence · Computer Science 2026-02-20 Gali Noti , Kate Donahue , Jon Kleinberg , Sigal Oren

The rise and spread of antibiotic resistance causes worsening medical cost and mortality especially for life-threatening bacteria infections, thereby posing a major threat to global health. Prescribing behavior of physicians is one of the…

Populations and Evolution · Quantitative Biology 2018-10-23 Xingru Chen , Feng Fu

AI has the potential to augment human decision making. However, even high-performing models can produce inaccurate predictions when deployed. These inaccuracies, combined with automation bias, where humans overrely on AI predictions, can…

Human-Computer Interaction · Computer Science 2025-08-12 Sarah Jabbour , David Fouhey , Nikola Banovic , Stephanie D. Shepard , Ella Kazerooni , Michael W. Sjoding , Jenna Wiens

When an algorithm provides risk assessments, we typically think of them as helpful inputs to human decisions, such as when risk scores are presented to judges or doctors. However, a decision-maker may react not only to the information…

Machine Learning · Computer Science 2025-11-04 Bryce McLaughlin , Jann Spiess

Antibiotic resistance, which is a serious healthcare issue, emerges due to uncontrolled and repeated antibiotic use that causes bacteria to mutate and develop resistance to antibiotics. The Antibiotics Time Machine Problem aims to come up…

Optimization and Control · Mathematics 2025-01-22 Deniz Tuncer , Burak Kocuk

The use of machine learning to guide clinical decision making has the potential to worsen existing health disparities. Several recent works frame the problem as that of algorithmic fairness, a framework that has attracted considerable…

Machine Learning · Statistics 2021-06-16 Stephen R. Pfohl , Agata Foryciarz , Nigam H. Shah

Algorithms learned from data are increasingly used for deciding many aspects in our life: from movies we see, to prices we pay, or medicine we get. Yet there is growing evidence that decision making by inappropriately trained algorithms may…

Artificial Intelligence · Computer Science 2017-08-03 Indre Zliobaite

When machine-learning algorithms are used in high-stakes decisions, we want to ensure that their deployment leads to fair and equitable outcomes. This concern has motivated a fast-growing literature that focuses on diagnosing and addressing…

Computers and Society · Computer Science 2023-09-26 Talia Gillis , Bryce McLaughlin , Jann Spiess

People's decision-making abilities often fail to improve or may even erode when they rely on AI for decision-support, even when the AI provides informative explanations. We argue this is partly because people intuitively seek contrastive…

Human-Computer Interaction · Computer Science 2025-03-20 Zana Buçinca , Siddharth Swaroop , Amanda E. Paluch , Finale Doshi-Velez , Krzysztof Z. Gajos

Scientific publications about machine learning in healthcare are often about implementing novel methods and boosting the performance - at least from a computer science perspective. However, beyond such often short-lived improvements, much…

We introduce a novel framework for incorporating human expertise into algorithmic predictions. Our approach leverages human judgment to distinguish inputs which are algorithmically indistinguishable, or "look the same" to predictive…

Machine Learning · Computer Science 2024-10-31 Rohan Alur , Manish Raghavan , Devavrat Shah

Mathematical models are increasing adopted for setting targets for disease prevention and control. As model-informed policies are implemented, however, the inaccuracies of some forecasts become apparent, for example overprediction of…

Timely transition from intravenous (IV) to oral antibiotic therapy shortens hospital stays, reduces catheter-related infections, and lowers healthcare costs, yet one in five patients in England remain on IV antibiotics despite meeting…

Machine Learning · Computer Science 2026-03-10 Magnus Ross , Nel Swanepoel , Akish Luintel , Emma McGuire , Ingemar J. Cox , Steve Harris , Vasileios Lampos

Bacteria develop resistance to antibiotics through various mechanisms, with the specific mechanism depending on the drug-bacteria pair. It remains unclear, however, which resistance mechanism best supports favorable treatment outcomes,…

Populations and Evolution · Quantitative Biology 2025-11-06 Ailin Zhang , Shigui Ruan , Xi Huo

Large language models are increasingly used in decision-making tasks that require them to process information from a variety of sources, including both human experts and other algorithmic agents. How do LLMs weigh the information provided…

Artificial Intelligence · Computer Science 2026-02-26 Jessica Y. Bo , Lillio Mok , Ashton Anderson

Policy learning algorithms are widely used in areas such as personalized medicine and advertising to develop individualized treatment regimes. However, most methods force a decision even when predictions are uncertain, which is risky in…

Machine Learning · Computer Science 2026-01-30 Ayush Sawarni , Jikai Jin , Justin Whitehouse , Vasilis Syrgkanis

In this work, we empirically examine human-AI decision-making in the presence of explanations based on predicted outcomes. This type of explanation provides a human decision-maker with expected consequences for each decision alternative at…

Human-Computer Interaction · Computer Science 2022-08-31 Johannes Jakubik , Jakob Schöffer , Vincent Hoge , Michael Vössing , Niklas Kühl

Most clinical AI systems operate as prediction engines -- producing labels or risk scores -- yet real clinical reasoning is a time-bounded, sequential control problem under uncertainty. Clinicians interleave information gathering with…

Artificial Intelligence · Computer Science 2026-01-21 Dipayan Sengupta , Saumya Panda

In the emerging era of big data, larger available clinical datasets and computational advances have sparked a massive interest in machine learning-based approaches. The number of manuscripts related to machine learning or artificial…

Machine Learning · Statistics 2020-06-29 Julius M. Kernbach , Victor E. Staartjes
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