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Antimicrobial protocols - using substances such as antibiotics or disinfectants - remain the preferred option for preventing the spread of pathogenic bacteria. However, bacteria can develop mechanisms to reduce their antimicrobial…

Populations and Evolution · Quantitative Biology 2026-02-17 Nerea Martínez-López , Niclas Nordholt , Frank Schreiber , Míriam R. García

There is significant interest in deploying machine learning algorithms for diagnostic radiology, as modern learning techniques have made it possible to detect abnormalities in medical images within minutes. While machine-assisted diagnoses…

Data Structures and Algorithms · Computer Science 2022-12-21 Woo-Hyung Cho , Shane Henderson , David Shmoys

In robust decision-making under non-Bayesian uncertainty, different robust optimization criteria, such as maximin performance, minimax regret, and maximin ratio, have been proposed. In many problems, all three criteria are well-motivated…

Optimization and Control · Mathematics 2024-03-20 Jerry Anunrojwong , Santiago R. Balseiro , Omar Besbes

This paper extends my research applying statistical decision theory to treatment choice with sample data, using maximum regret to evaluate the performance of treatment rules. The specific new contribution is to study as-if optimization…

Econometrics · Economics 2021-10-05 Charles F. Manski

Predictive modelling is vital to guide preventive efforts. Whilst large-scale prospective cohort studies and a diverse toolkit of available machine learning (ML) algorithms have facilitated such survival task efforts, choosing the…

Undesired bias afflicts both human and algorithmic decision making, and may be especially prevalent when information processing trade-offs incentivize the use of heuristics. One primary example is \textit{statistical discrimination} --…

Decisions in organizations are about evaluating alternatives and choosing the one that would best serve organizational goals. To the extent that the evaluation of alternatives could be formulated as a predictive task with appropriate…

Human-Computer Interaction · Computer Science 2022-06-30 Charles Wan , Rodrigo Belo , Leid Zejnilović

One of the key challenges when developing a predictive model is the capability to describe the domain knowledge and the cause-effect relationships in a simple way. Decision rules are a useful and important methodology in this context,…

Machine Learning · Computer Science 2021-10-19 Francisco Valente , Jorge Henriques , Simão Paredes , Teresa Rocha , Paulo de Carvalho , João Morais

Estimation of individual treatment effects is commonly used as the basis for contextual decision making in fields such as healthcare, education, and economics. However, it is often sufficient for the decision maker to have estimates of…

Machine Learning · Computer Science 2020-08-13 Maggie Makar , Fredrik D. Johansson , John Guttag , David Sontag

The integration of users and experts in machine learning is a widely studied topic in artificial intelligence literature. Similarly, human-computer interaction research extensively explores the factors that influence the acceptance of AI as…

Human-Computer Interaction · Computer Science 2024-08-05 Jaroslaw Kornowicz , Kirsten Thommes

Motivation: HIV is difficult to treat because its virus mutates at a high rate and mutated viruses easily develop resistance to existing drugs. If the relationships between mutations and drug resistances can be determined from historical…

Quantitative Methods · Quantitative Biology 2019-07-08 Li Xing , Mary Lesperance , Xuekui Zhang

As artificial intelligence becomes more powerful and a ubiquitous presence in daily life, it is imperative to understand and manage the impact of AI systems on our lives and decisions. Modern ML systems often change user behavior (e.g.…

Artificial Intelligence · Computer Science 2022-03-31 Matija Franklin , Hal Ashton , Rebecca Gorman , Stuart Armstrong

Machine Learning (ML) algorithms are vital for supporting clinical decision-making in biomedical informatics. However, their predictive performance can vary across demographic groups, often due to the underrepresentation of historically…

Machine Learning · Computer Science 2025-03-04 Ioannis Bilionis , Ricardo C. Berrios , Luis Fernandez-Luque , Carlos Castillo

Machine learning models are increasingly integrated into societally critical applications such as recidivism prediction and medical diagnosis, thanks to their superior predictive power. In these applications, however, full automation is…

Human-Computer Interaction · Computer Science 2020-03-18 Vivian Lai , Samuel Carton , Chenhao Tan

Uncertainty in artificial intelligence (AI) predictions poses urgent legal and ethical challenges for AI-assisted decision-making. We examine two algorithmic interventions that act as guardrails for human-AI collaboration: selective…

Computers and Society · Computer Science 2025-08-12 Holli Sargeant , Mackenzie Jorgensen , Arina Shah , Adrian Weller , Umang Bhatt

We introduce a novel framework for human-AI collaboration in prediction and decision tasks. Our approach leverages human judgment to distinguish inputs which are algorithmically indistinguishable, or "look the same" to any feasible…

Machine Learning · Computer Science 2024-10-21 Rohan Alur , Loren Laine , Darrick K. Li , Dennis Shung , Manish Raghavan , Devavrat Shah

Strong empirical evidence that one machine-learning algorithm A outperforms another one B ideally calls for multiple trials optimizing the learning pipeline over sources of variation such as data sampling, data augmentation, parameter…

Machine learning algorithms enable advanced decision making in contemporary intelligent systems. Research indicates that there is a tradeoff between their model performance and explainability. Machine learning models with higher performance…

Machine Learning · Computer Science 2022-06-23 Lukas-Valentin Herm , Kai Heinrich , Jonas Wanner , Christian Janiesch

Model multiplicity refers to the existence of multiple machine learning models that describe the data equally well but may produce different predictions on individual samples. In medicine, these models can admit conflicting predictions for…

The research area of algorithms with predictions has seen recent success showing how to incorporate machine learning into algorithm design to improve performance when the predictions are correct, while retaining worst-case guarantees when…

Machine Learning · Computer Science 2022-12-06 Michael Dinitz , Sungjin Im , Thomas Lavastida , Benjamin Moseley , Sergei Vassilvitskii