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In clinical trials, minimum clinically important difference (MCID) has attracted increasing interest as an important supportive clinical and statistical inference tool. Many estimation methods have been developed based on various…

Methodology · Statistics 2013-12-02 A. S. Hedayat , Junhui Wang , Tu Xu

Introduction: For COVID-19 patients accurate prediction of disease severity and mortality risk would greatly improve care delivery and resource allocation. There are many patient-related factors, such as pre-existing comorbidities that…

When modeling the demand in revenue management systems, a natural approach is to focus on a canonical interval of time, such as a week, so that we forecast the demand over each week in the selling horizon. Ideally, we would like to use…

Optimization and Control · Mathematics 2024-09-09 Weiyuan Li , Paat Rusmevichientong , Huseyin Topaloglu

We present an empirical algorithm to forecast the evolution of the number of COVID-19 symptomatic patients in the early stages of the pandemic spread and after strict social distancing interventions. The algorithm is based on a low…

Populations and Evolution · Quantitative Biology 2020-11-20 Luis Alvarez

Epidemic forecasts are only as good as the accuracy of epidemic measurements. Is epidemic data, particularly COVID-19 epidemic data, clean and devoid of noise? Common sense implies the negative answer. While we cannot evaluate the…

Populations and Evolution · Quantitative Biology 2023-04-25 Long MA , Piet Van Mieghem , Maksim Kitsak

Comparing how different populations have suffered under COVID-19 is a core part of ongoing investigations into how public policy and social inequalities influence the number of and severity of COVID-19 cases. But COVID-19 incidence can vary…

Populations and Evolution · Quantitative Biology 2022-11-17 Ryan Wilkinson , Marcus Roper

Since the beginning of the COVID-19 pandemic, many dashboards have emerged as useful tools to monitor the evolution of the pandemic, inform the public, and assist governments in decision making. Our goal is to develop a globally applicable…

Intent of this research is to explore how mathematical models, specifically Susceptible-Infected-Removed (SIR) model, can be utilized to forecast peak outbreak timeline of COVID-19 epidemic amongst a population of interest starting from the…

Populations and Evolution · Quantitative Biology 2020-09-14 Amit Tewari

Forecasting infectious disease outbreaks is hard. Forecasting emerging infectious diseases with limited historical data is even harder. In this paper, we investigate ways to improve emerging infectious disease forecasting under operational…

The unprecedented global crisis brought about by the COVID-19 pandemic has sparked numerous efforts to create predictive models for the detection and prognostication of SARS-CoV-2 infections with the goal of helping health systems allocate…

Infectious disease modeling and forecasting have played a key role in helping assess and respond to epidemics and pandemics. Recent work has leveraged data on disease peak infection and peak hospital incidence to fit compartmental models…

Difference-in-differences (DiD) is one of the most popular approaches for empirical research in economics, political science, and beyond. Identification in these models is based on the conditional parallel trends assumption: In the absence…

Econometrics · Economics 2025-10-13 Philipp Bach , Sven Klaassen , Jannis Kueck , Mara Mattes , Martin Spindler

The COVID-19 disease has forced countries to make a considerable collaborative effort between scientists and governments to provide indicators to suitable follow-up the pandemic's consequences. Mathematical modeling plays a crucial role in…

Populations and Evolution · Quantitative Biology 2020-12-29 Patricio Cumsille , Oscar Rojas-Díaz , Pablo Moisset de Espanés

There is increasing interest in comparing institutions delivering healthcare in terms of disease-specific quality indicators (QIs) that capture processes or outcomes showing variations in the care provided. Such comparisons can be framed in…

Methodology · Statistics 2020-09-07 Bo Chen , Keith A. Lawson , Antonio Finelli , Olli Saarela

Epidemic forecasting has become an integral part of real-time infectious disease outbreak response. While collaborative ensembles composed of statistical and machine learning models have become the norm for real-time forecasting,…

Early and timely prediction of patient care demand not only affects effective resource allocation but also influences clinical decision-making as well as patient experience. Accurately predicting patient care demand, however, is a…

Machine Learning · Computer Science 2024-04-30 Annie Hu , Samuel Stockman , Xun Wu , Richard Wood , Bangdong Zhi , Oliver Y. Chén

Sustaining regular and infectious care during an infectious outbreak requires adequate management support for capacity allocation for regular and infectious patients. During the COVID-19 pandemic, hospitals faced severe challenges,…

Optimization and Control · Mathematics 2024-10-17 Stef Baas , Sander Dijkstra , Richard J. Boucherie , Anne Zander

Importance: Alternative methods for hospital utilization forecasting, essential information in hospital crisis planning, are necessary in a novel pandemic when traditional data sources such as disease testing are limited. Objective:…

Introduction: The aim of our retrospective study was to quantify the impact of Covid-19 on the temporal distribution of Emergency Medical Services (EMS) demand in Travis County, Austin, Texas and propose a robust model to forecast Covid-19…

Applications · Statistics 2021-10-05 Yangxinyu Xie , David Kulpanowski , Joshua Ong , Evdokia Nikolova , Ngoc Mai Tran

The COVID-19 pandemic has posed a heavy burden to the healthcare system worldwide and caused huge social disruption and economic loss. Many deep learning models have been proposed to conduct clinical predictive tasks such as mortality…

Machine Learning · Computer Science 2024-01-24 Junyi Gao , Yinghao Zhu , Wenqing Wang , Yasha Wang , Wen Tang , Ewen M. Harrison , Liantao Ma