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Inspired by concepts developed for fermionic systems in the framework of condensed matter physics, topology and topological states are recently being explored also in bosonic systems. The possibility of engineering systems with…

A low-cost device for registration-free quantitative phase microscopy (QPM) based on the transport of intensity equation (TIE) of cells in continuous flow is presented. The method uses acoustic focusing to align cells into a single plane…

We theoretically propose a new method in cavity- and surface-enhanced Raman spectroscopy (SERS) with improved temporal resolution in the measurement of stochastic Raman spectral fluctuations. Our approach combines Fourier spectroscopy and…

Optics · Physics 2025-07-02 Colburn Cobb-Bruno , Hendrik Utzat

Time-domain sampling of arbitrary electric fields with sub-cycle resolution enables a complete time-frequency analysis of a system's response to electromagnetic illumination. This provides access to dynamic information that is not provided…

Identifying pathogens in complex samples such as blood, urine, and wastewater is critical to detect infection and inform optimal treatment. Surface-enhanced Raman spectroscopy (SERS) and machine learning (ML) can distinguish among multiple…

We propose a two-step pulse observation method to enhance frequency stability for coherent population trapping (CPT) atomic clocks. The proposed method is a Raman-Ramsey scheme with low light intensity at resonance observation, and provides…

Atomic Physics · Physics 2014-12-15 Yuichiro Yano , Shigeyoshi Goka , Masatoshi Kajita

Background These last decades have seen the emergence and development of cell-based therapies, notably those based on mesenchymal stromal cells (MSCs). The advancement of these promising treatments requires increasing the throughput of…

The chaotic nature of x-ray free-electron-laser pulses is a major bottleneck that has limited the joint temporal and spectral resolution of spectroscopic measurements. We show how to use the stochastic x-ray field statistics to overcome…

Optics · Physics 2021-02-15 Stefano M. Cavaletto , Daniel Keefer , Shaul Mukamel

Confocal Raman spectroscopy is a versatile, non-invasive investigation tool and a major workhorse for graphene characterization. Here we show that the experimentally observed Raman 2D line width is a measure of nanometer-scale strain…

We present a flexible and efficient ultrafast time-resolved spontaneous Raman spectroscopy setup to study collective excitation and quasi-particle dynamics in quantum matter. The setup has a broad energy tuning range extending from the…

Driven by many applications in a wide span of scientific fields, a myriad of advanced ultrafastimaging techniques have emerged in the last decade, featuring record-high imaging speeds abovea trillion-frame-per-second with long sequence…

Precise manipulation of fluids and objects on the micro scale is seldom a simple task, but nevertheless crucial for many applications in life sciences and chemical engineering. We present a microfluidic chip fabricated in silicon-glass,…

We show that it is possible to realize simultaneous Raman lasing at two different frequencies using a double-$\Lambda$ system pumped by a bi-frequency field. The Raman lasers are phase-locked to one another, and the beat-frequency matches…

Quantum Physics · Physics 2018-05-30 Hadiseh Alaeian , Selim Shahriar

Over the past few decades, researchers have developed several approaches such as the Reference Phantom Method (RPM) to estimate ultrasound attenuation coefficient (AC) and backscatter coefficient (BSC). AC and BSC can help to discriminate…

Medical Physics · Physics 2017-12-12 Kajoli Banerjee Krishnan , Nithin Nagaraj , Nitin Singhal , Shalini Thapar , Komal Yadav

Integrating graphene with plasmonic nanostructures results in multifunctional hybrid systems with enhanced performance for numerous applications. In this work, we take advantage of the remarkable mechanical properties of graphene to combine…

Multiplexed immuno-fluorescence tissue imaging, allowing simultaneous detection of molecular properties of cells, is an essential tool for characterizing the complex cellular mechanisms in translational research and clinical practice. New…

A fluorescence correlation spectroscopy (FCS) system based on two independent measurement volumes is presented. The optical setup and data acquisition hardware are detailed, as well as a complete protocol to control the location, size and…

Optics · Physics 2009-08-26 P. Ferrand , M. Pianta , A. Kress , A. Aillaud , H. Rigneault , D. Marguet

State-of-the-art microscopes use intense lasers that can severely disturb biological processes, function and viability. This introduces hard limits on performance that only quantum photon correlations can overcome. Here we demonstrate this…

A broadband sound absorption attained by a deep-subwavelength structure is of great interest to the noise control community especially for extremely low frequencies (20-100 Hz) in room acoustics. Coupling multiple different resonant unit…

Applied Physics · Physics 2021-01-12 Jun Ji , Dongting Li , Yong Li , Yun Jing

We introduce the first method to enable an optical amplification of a coherent Raman spectroscopy signal called radio frequency Doppler Raman spectroscopy. Doppler Raman measurements amplify the optical signals in coherent Raman…