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Advancement in digital pathology and artificial intelligence has enabled deep learning-based computer vision techniques for automated disease diagnosis and prognosis. However, WSIs present unique computational and algorithmic challenges.…
Out-of-focus microscopy lens in digital pathology is a critical bottleneck in high-throughput Whole Slide Image (WSI) scanning platforms, for which pixel-level automated Focus Quality Assessment (FQA) methods are highly desirable to help…
Histopathological analysis of Whole Slide Images (WSIs) has seen a surge in the utilization of deep learning methods, particularly Convolutional Neural Networks (CNNs). However, CNNs often fall short in capturing the intricate spatial…
The field of digital pathology has seen a proliferation of deep learning models in recent years. Despite substantial progress, it remains rare for other researchers and pathologists to be able to access models published in the literature…
Convolutional neural networks (CNNs) have been recently used for a variety of histology image analysis. However, availability of a large dataset is a major prerequisite for training a CNN which limits its use by the computational pathology…
Despite great advances, molecular cancer pathology is often limited to the use of a small number of biomarkers rather than the whole transcriptome, partly due to computational challenges. Here, we introduce a novel architecture of Deep…
The microscopic examination of surgical tissue remains a cornerstone of disease classification but relies on subjective interpretations and access to highly specialized experts, which can compromise accuracy and clinical care. While…
Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…
Histopathological images contain rich phenotypic information that can be used to monitor underlying mechanisms contributing to diseases progression and patient survival outcomes. Recently, deep learning has become the mainstream…
Deep Convolutional Neural Networks (CNNs) are the state of the art systems for image classification and scene understating. However, such techniques are computationally intensive and involve highly regular parallel computation. CNNs can…
Image analysis tasks in computational pathology are commonly solved using convolutional neural networks (CNNs). The selection of a suitable CNN architecture and hyperparameters is usually done through exploratory iterative optimization,…
Convolutional Neural Networks (CNNs) are currently adopted to solve an ever greater number of problems, ranging from speech recognition to image classification and segmentation. The large amount of processing required by CNNs calls for…
Recent advances in whole slide imaging (WSI) technology have led to the development of a myriad of computer vision and artificial intelligence (AI) based diagnostic, prognostic, and predictive algorithms. Computational Pathology (CPath)…
With the development of deep learning, the performance of hyperspectral image (HSI) classification has been greatly improved in recent years. The shortage of training samples has become a bottleneck for further improvement of performance.…
Tissue characterization has long been an important component of Computer Aided Diagnosis (CAD) systems for automatic lesion detection and further clinical planning. Motivated by the superior performance of deep learning methods on various…
Digital pathology offers a groundbreaking opportunity to transform clinical practice in histopathological image analysis, yet faces a significant hurdle: the substantial file sizes of pathological Whole Slide Images (WSI). While current…
Convolutional neural networks (CNNs) define the current state-of-the-art for image recognition. With their emerging popularity, especially for critical applications like medical image analysis or self-driving cars, confirmability is…
Convolutional Neural Network (CNN) based Deep Learning (DL) has achieved great progress in many real-life applications. Meanwhile, due to the complex model structures against strict latency and memory restriction, the implementation of CNN…
Deep Learning (DL) approaches have been providing state-of-the-art performance in different modalities in the field of medical imagining including Digital Pathology Image Analysis (DPIA). Out of many different DL approaches, Deep…
To increase the objectivity and accuracy of pathologists' work, artificial neural network(ANN) methods have been generally needed in the segmentation, classification, and detection of histopathological WSI. In this paper, WSI analysis…