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The advancement of the neuroscientific imaging techniques has produced an unprecedented size of neural cell imaging data, which calls for automated processing. In particular, identification of cells from two photon images demands…

Image and Video Processing · Electrical Eng. & Systems 2019-09-26 Si-Baek Seong , Hae-Jeong Park

Pattern recognition and image classification are essential tasks in machine vision. Autonomous vehicles, for example, require being able to collect the complex information contained in a changing environment and classify it in real time.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Aisha Kanwal , Graeme E. Johnstone , Fahimeh Dehkhoda , Johannes H. Herrnsdorf , Robert K. Henderson , Martin D. Dawson , Xavier Porte , Michael J. Strain

This paper presents an unsupervised algorithm for nonlinear unmixing of hyperspectral images. The proposed model assumes that the pixel reflectances result from a nonlinear function of the abundance vectors associated with the pure spectral…

Machine Learning · Statistics 2015-06-05 Yoann Altmann , Nicolas Dobigeon , Steve McLaughlin , Jean-Yves Tourneret

Vision foundation models (FMs) are accelerating the development of digital pathology algorithms and transforming biomedical research. These models learn, in a self-supervised manner, to represent histological features in highly…

In this paper, we present a graph-based semi-supervised framework for hyperspectral image classification. We first introduce a novel superpixel algorithm based on the spectral covariance matrix representation of pixels to provide a better…

Computer Vision and Pattern Recognition · Computer Science 2019-05-16 Philip Sellars , Angelica Aviles-Rivero , Nicolas Papadakis , David Coomes , Anita Faul , Carola-Bibane Schönlieb

Investigation of cell structure is hardly imaginable without bright-field microscopy. Numerous modifications such as depth-wise scanning or videoenhancement make this method being state-of-the-art. This raises a question what maximal…

Image and Video Processing · Electrical Eng. & Systems 2020-10-29 Kirill Lonhus , Renata Rychtarikova , Ganna Platonova , Dalibor Stys

Results: We present an application that enables the quantitative analysis of multichannel 5-D (x, y, z, t, channel) and large montage confocal fluorescence microscopy images. The image sequences show stem cells together with blood vessels,…

Subspace clustering is a powerful unsupervised approach for hyperspectral image (HSI) analysis, but its high computational and memory costs limit scalability. Superpixel segmentation can improve efficiency by reducing the number of data…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Xianlu Li , Nicolas Nadisic , Shaoguang Huang , Aleksandra Pizurica

When it is polarised, a cell develops an asymmetric distribution of specific molecular markers, cytoskeleton and cell membrane shape. Polarisation can occur spontaneously or be triggered by external signals, like gradients of signalling…

Analysis of PDEs · Mathematics 2013-01-18 Vincent Calvez , Nicolas Meunier , Nicolas Muller , Raphael Voituriez

Fungal simulation and control are considered crucial techniques in Bio-Art creation. However, coding algorithms for reliable fungal simulations have posed significant challenges for artists. This study equates fungal morphology simulation…

Graphics · Computer Science 2024-09-10 Kexin Wang , Ivy He , Jinke Li , Ali Asadipour , Yitong Sun

Fluorescence lifetime imaging microscopy (FLIM) is a powerful quantitative technique that provides metabolic and molecular contrast, offering strong translational potential for label-free, real-time diagnostics. However, its clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Paloma Casteleiro Costa , Parnian Ghapandar Kashani , Xuhui Liu , Alexander Chen , Ary Portes , Julien Bec , Laura Marcu , Aydogan Ozcan

Current biological and medical research is aimed at obtaining a detailed spatiotemporal map of a live cell's interior to describe and predict cell's physiological state. We present here an algorithm for complete 3-D modelling of cellular…

Quantitative Methods · Quantitative Biology 2017-04-03 Renata Rychtarikova , Tomas Nahlik , Kevin Shi , Daria Malakhova , Petr Machacek , Rebecca Smaha , Jan Urban , Dalibor Stys

The necessity of large amounts of labeled data to train deep models, especially in medical imaging creates an implementation bottleneck in resource-constrained settings. In Insite (labelINg medical imageS usIng submodular funcTions and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Akshat Gautam , Anurag Shandilya , Akshit Srivastava , Venkatapathy Subramanian , Ganesh Ramakrishnan , Kshitij Jadhav

Pixel and superpixel classifiers have become essential tools for EM segmentation algorithms. Training these classifiers remains a major bottleneck primarily due to the requirement of completely annotating the dataset which is tedious,…

Computer Vision and Pattern Recognition · Computer Science 2014-06-17 Toufiq Parag , Stephen Plaza , Louis Scheffer

Studying the growth and metabolism of microbes provides critical insights into their evolutionary adaptations to harsh environments, which are essential for microbial research and biotechnology applications. In this study, we developed an…

Image and Video Processing · Electrical Eng. & Systems 2025-05-06 Shuang Zhang , Carleton Coffin , Karyn L. Rogers , Catherine Ann Royer , Ge Wang

Disease progression simulation is a crucial area of research that has significant implications for clinical diagnosis, prognosis, and treatment. One major challenge in this field is the lack of continuous medical imaging monitoring of…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Kaizhao Liang , Xu Cao , Kuei-Da Liao , Tianren Gao , Wenqian Ye , Zhengyu Chen , Jianguo Cao , Tejas Nama , Jimeng Sun

This paper describes a new algorithm for hyperspectral image unmixing. Most of the unmixing algorithms proposed in the literature do not take into account the possible spatial correlations between the pixels. In this work, a Bayesian model…

Methodology · Statistics 2012-09-05 Olivier Eches , Nicolas Dobigeon , Jean-Yves Tourneret

We are interested in inferring object segmentation by leveraging only object class information, and by considering only minimal priors on the object segmentation task. This problem could be viewed as a kind of weakly supervised segmentation…

Computer Vision and Pattern Recognition · Computer Science 2015-04-27 Pedro O. Pinheiro , Ronan Collobert

Single cell segmentation is critical and challenging in live cell imaging data analysis. Traditional image processing methods and tools require time-consuming and labor-intensive efforts of manually fine-tuning parameters. Slight variations…

Quantitative Methods · Quantitative Biology 2019-04-24 Weikang Wang , David A. Taft , Yi-Jiun Chen , Jingyu Zhang , Callen T. Wallace , Min Xu , Simon C. Watkins , Jianhua Xing

This paper proposes an unsupervised anomaly detection technique for image-based plant disease diagnosis. The construction of large and publicly available datasets containing labeled images of healthy and diseased crop plants led to growing…

Computer Vision and Pattern Recognition · Computer Science 2021-09-09 Ryoya Katafuchi , Terumasa Tokunaga