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This work explores a new approach for optimization in the field of microfluidics, using the combination of CFD (Computational Fluid Dynamics), and Machine Learning techniques. The objective of this combination is to enable global…

This paper presents a method for simultaneous optimization of the outer shape and internal topology of aircraft wings, with the objective of minimizing drag subject to lift and compliance constraints for multiple load cases. The physics are…

Computational Engineering, Finance, and Science · Computer Science 2023-05-01 Lukas C. Høghøj , Cian Conlan-Smith , Ole Sigmund , Casper Schousboe Andreasen

Highly-optimized complex transport networks serve crucial functions in many man-made and natural systems such as power grids and plant or animal vasculature. Often, the relevant optimization functional is non-convex and characterized by…

Biological Physics · Physics 2016-09-23 Henrik Ronellenfitsch , Eleni Katifori

Inertial fluid flow deformation around pillars in a microchannel is a new method for controlling fluid flow. Sequences of pillars have been shown to produce a rich phase space with a wide variety of flow transformations. Previous work has…

The protein folding problem must ultimately be solved on all length scales from the atomic up through a hierarchy of complicated structures. By analyzing the stability of the folding process using physics and mathematics, this paper shows…

Biological Physics · Physics 2015-05-28 Walter Simmons , Joel L. Weiner

Uniform flow distribution across parallel channels directly impacts the performance and efficiency of many fluid and energy systems. However, designing efficient flow manifolds that ensure uniform flow distribution remains a challenge. This…

Fluid Dynamics · Physics 2025-10-06 Sanjay Vermani , Nitish Anand

Soft robotics has emerged as the standard solution for grasping deformable objects, and has proven invaluable for mobile robotic exploration in extreme environments. However, despite this growth, there are no widely adopted computational…

Robotics · Computer Science 2024-07-11 Yue Xie , Josh Pinskier , Lois Liow , David Howard , Fumiya Iida

We consider the problem of finding optimal shapes of fluid domains. The fluid obeys the Navier--Stokes equations. Inside a holdall container we use a phase field approach using diffuse interfaces to describe the domain of free flow. We…

Optimization and Control · Mathematics 2014-05-15 Harald Garcke , Claudia Hecht , Michael Hinze , Christian Kahle

Structural optimization (topology, shapes, sizing) is an important tool for facilitating the emergence of new concepts in structural design. Normally, topology optimization is carried out at the early stage of design and then shape and…

Optimization and Control · Mathematics 2021-03-16 Ghislain Raze , Joseph Morlier

We derive general depth-integrated model equations for overland flows featuring the evolution of suspended sediment that may be eroded from or deposited onto the underlying topography ('morphodynamics'). The resulting equations include…

Fluid Dynamics · Physics 2023-06-29 Jake Langham , Mark J. Woodhouse , Andrew J. Hogg , Luke T. Jenkins , Jeremy C. Phillips

Biofilms pose significant problems for engineers in diverse fields, such as marine science, bioenergy, and biomedicine, where effective biofilm control is a long-term goal. The adhesion and surface mechanics of biofilms play crucial roles…

Biological Physics · Physics 2022-12-22 Hanfeng Zhai , Jingjie Yeo

This work concerns a structural topology optimisation problem for 4D printing based on the phase field approach. The concept of 4D printing as a targeted evolution of 3D printed structures can be realised in a two-step process. One first…

Optimization and Control · Mathematics 2023-05-03 Harald Garcke , Kei Fong Lam , Robert Nürnberg , Andrea Signori

The problem of maneuvering a vehicle through a race course in minimum time requires computation of both longitudinal (brake and throttle) and lateral (steering wheel) control inputs. Unfortunately, solving the resulting nonlinear optimal…

Robotics · Computer Science 2019-02-05 Nitin R. Kapania , John Subosits , J Christian Gerdes

Resource-intensive computations are a major factor that limits the effectiveness of automated machine learning solutions. In the paper, we propose a modular approach that can be used to increase the quality of evolutionary optimization for…

Machine Learning · Computer Science 2023-01-13 Nikolay O. Nikitin , Sergey Teryoshkin , Valerii Pokrovskii , Sergey Pakulin , Denis Nasonov

Shear stress is an important physical factor that regulates proliferation, migration and morphogenesis. In particular, the homeostasis of blood vessels is dependent on shear stress. To mimic this process ex vivo, efforts have been made to…

Soft Condensed Matter · Physics 2013-01-15 K. Youssef , J. J. Mack , M. L. Iruela-Arispe , L. -S. Bouchard

Trajectory tracking for microswimmers remains a key challenge in microrobotics, where low-Reynolds-number dynamics make control design particularly complex. In this work, we formulate the trajectory tracking problem as an optimal control…

Robotics · Computer Science 2026-02-11 Lucas Palazzolo , Mickaël Binois , Laëtitia Giraldi

Additive manufacturing is a free-form manufacturing technique in which parts are built in a layer-by-layer manner. Laser powder bed fusion is one of the popular techniques used to fabricate metal parts. However, it induces residual stress…

Computational Engineering, Finance, and Science · Computer Science 2021-05-07 Takao Miki , Takayuki Yamada

Microfiltration technology is a widely used engineering strategy for fresh water production and water treatment. The major concern in many applications is the formation of a biological fouling layer leading to increased hydraulic resistance…

Biological Physics · Physics 2021-04-12 V. Luongo , M. R. Mattei , L. Frunzo , B. D'Acunto , K. Gupta , S. Chellam , N. G. Cogan

Fluidic devices are crucial components in many industrial applications involving fluid mechanics. Computational design of a high-performance fluidic system faces multifaceted challenges regarding its geometric representation and physical…

Graphics · Computer Science 2022-09-27 Yifei Li , Tao Du , Sangeetha Grama Srinivasan , Kui Wu , Bo Zhu , Eftychios Sifakis , Wojciech Matusik

The effect of substrate topography on the settlement of coral larvae in wave-driven oscillatory flow is investigated using computational fluid dynamics coupled to a 2D agent-based simulation of individual larvae. Substrate topography…

Fluid Dynamics · Physics 2025-05-30 Daniel Gysbers , Mark A. Levenstein , Gabriel Juarez