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When an epidemic spreads into a population, it is often unpractical or impossible to have a continuous monitoring of all subjects involved. As an alternative, algorithmic solutions can be used to infer the state of the whole population from…

Populations and Evolution · Quantitative Biology 2021-05-12 Abhishek Tomy , Matteo Razzanelli , Francesco Di Lauro , Daniela Rus , Cosimo Della Santina

The outbreak of COVID-19, beginning in 2019 and continuing through the time of writing, has led to renewed interest in the mathematical modeling of infectious disease. Recent works have focused on partial differential equation (PDE) models,…

Populations and Evolution · Quantitative Biology 2022-10-26 Malú Grave , Alex Viguerie , Gabriel F. Barros , Alessandro Reali , Roberto F. S. Andrade , Alvaro L. G. A. Coutinho

The global spread of the COVID-19 pandemic has followed complex pathways, largely attributed to the high virus infectivity, human travel patterns, and the implementation of multiple mitigation measures. The resulting geographic patterns…

Physics and Society · Physics 2021-06-29 Troy McMahon , Adrian Chan , Shlomo Havlin , Lazaros K. Gallos

Motivated by the increasing number of COVID-19 cases that have been observed in many countries after the vaccination and relaxation of non-pharmaceutical interventions, we propose a mathematical model on time-varying networks for the spread…

Dynamical Systems · Mathematics 2022-03-09 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

The spread of COVID-19 has been greatly impacted by regulatory policies and behavior patterns that vary across counties, states, and countries. Population-level dynamics of COVID-19 can generally be described using a set of ordinary…

Applications · Statistics 2022-04-11 Joshua P. Keller , Tianjian Zhou , Andee Kaplan , G. Brooke Anderson , Wen Zhou

Epidemic modeling is an essential tool to understand the spread of the novel coronavirus and ultimately assist in disease prevention, policymaking, and resource allocation. In this article, we establish a state of the art interface between…

Applications · Statistics 2020-12-17 Li Wang , Guannan Wang , Lei Gao , Xinyi Li , Shan Yu , Myungjin Kim , Yueying Wang , Zhiling Gu

Many countries have experienced at least two waves of the COVID-19 pandemic. The second wave is far more dangerous as distinct strains appear more harmful to human health, but it stems from the complacency about the first wave. This paper…

Populations and Evolution · Quantitative Biology 2022-06-29 Edilson F. Arruda , Tarun Sharma , Rodrigo e A. Alexandre , Sinnu Susan Thomas

Throughout the course of an epidemic, the rate at which disease spreads varies with behavioral changes, the emergence of new disease variants, and the introduction of mitigation policies. Estimating such changes in transmission rates can…

Methodology · Statistics 2022-11-29 Jenny Huang , Raphaël Morsomme , David Dunson , Jason Xu

The analysis of contagion-diffusion processes in metapopulations is a powerful theoretical tool to study how mobility influences the spread of communicable diseases. Nevertheless, many metapopulation approaches use indistinguishable agents…

Physics and Society · Physics 2022-04-20 Pablo Valgañón , David Soriano-Paños , Alex Arenas , Jesús Gómez-Gardeñes

Deterministic models are developed for the spatial spread of epidemic diseases in geographical settings. The models are focused on outbreaks that arise from a small number of infected hosts imported into sub-regions of the geographical…

Populations and Evolution · Quantitative Biology 2018-01-08 Pierre Magal , Glenn F. Webb , Yixiang Wu

Our chances to halt epidemic outbreaks rely on how accurately we represent the population structure underlying the disease spread. When analyzing global epidemics this force us to consider metapopulation models taking into account intra-…

Populations and Evolution · Quantitative Biology 2007-12-10 Alexei Vazquez

In a world being hit by waves of COVID-19, vaccination is a light on the horizon. However, the roll-out of vaccination strategies and their influence on the pandemic are still open problems. In order to compare the effect of various…

Physics and Society · Physics 2021-04-23 N. L. Barreiro , C. I. Ventura , T. Govezensky , M. Núñez , P. G. Bolcatto , R. A. Barrio

We develop a minimalist compartmental model to study the impact of mobility restrictions in Italy during the Covid-19 outbreak. We show that an early lockdown shifts the epidemic in time, while that beyond a critical value of the lockdown…

To forecast the time dynamics of an epidemic, we propose a discrete stochastic model that unifies and generalizes previous approaches to the subject. Viewing a given population of individuals or groups of individuals with given health state…

Tracking the spread of infectious disease during a pandemic has posed a great challenge to the governments and health sectors on a global scale. To facilitate informed public health decision-making, the concerned parties usually rely on…

Methodology · Statistics 2023-06-05 Tejasv Bedi , Yanxun Xu , Qiwei Li

Network--based epidemic models that account for heterogeneous contact patterns are extensively used to predict and control the diffusion of infectious diseases. We use census and survey data to reconstruct a geo--referenced and…

Social and Information Networks · Computer Science 2026-05-19 Alessandro Celestini , Francesca Colaiori , Stefano Guarino , Enrico Mastrostefano , Lena Rebecca Zastrow

Mathematical models of SARS-CoV-2 spread are used for guiding the design of mitigation steps aimed at containing and decelerating the contagion, and at identifying impending breaches of health care system surge capacity. The challenges of…

Populations and Evolution · Quantitative Biology 2020-06-17 Daniela Calvetti , Alexander Hoover , Johnie Rose , Erkki Somersalo

In this paper we introduce a space-dependent multiscale model to describe the spatial spread of an infectious disease under uncertain data with particular interest in simulating the onset of the COVID-19 epidemic in Italy. While virus…

Populations and Evolution · Quantitative Biology 2021-08-31 Giulia Bertaglia , Walter Boscheri , Giacomo Dimarco , Lorenzo Pareschi

Since the beginning of the COVID-19 spreading, the number of studies on the epidemic models increased dramatically. It is important for policymakers to know how the disease will spread and what are the effects of the policies and…

Physics and Society · Physics 2022-01-06 Hao Liao , Ziqiang Wu , Alexandre Vidmer , Mingyang Zhou , Wei Chen

We propose a compartmental model for epidemiology wherein the population is split into groups with either comply or refuse to comply with protocols designed to slow the spread of a disease. Parallel to the disease spread, we assume that…

Dynamical Systems · Mathematics 2025-11-27 Christian Parkinson , Weinan Wang