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Increasing emphasis on data and quantitative methods in the biomedical sciences is making biological research more computational. Collecting, curating, processing, and analysing large genomic and imaging data sets poses major computational…

Quantitative Methods · Quantitative Biology 2021-09-22 Elisabeth Roesch , Joe G. Greener , Adam L. MacLean , Huda Nassar , Christopher Rackauckas , Timothy E. Holy , Michael P. H. Stumpf

In this paper we present BilevelJuMP, a new Julia package to support bilevel optimization within the JuMP framework. The package is a Julia library that enables the user to describe both upper and lower-level optimization problems using the…

Optimization and Control · Mathematics 2022-12-21 Joaquim Dias Garcia , Guilherme Bodin , Alexandre Street

JuMP is an open-source modeling language that allows users to express a wide range of optimization problems (linear, mixed-integer, quadratic, conic-quadratic, semidefinite, and nonlinear) in a high-level, algebraic syntax. JuMP takes…

Optimization and Control · Mathematics 2017-05-08 Iain Dunning , Joey Huchette , Miles Lubin

Biological systems with intertwined feedback loops pose a challenge to mathematical modeling efforts. Moreover, rare events, such as mutation and extinction, complicate system dynamics. Stochastic simulation algorithms are useful in…

Quantitative Methods · Quantitative Biology 2018-12-10 Alfonso Landeros , Timothy Stutz , Kevin L. Keys , Alexander Alekseyenko , Janet S. Sinsheimer , Kenneth Lange , Mary Sehl

The Julia programming language has evolved into a modern alternative to fill existing gaps in scientific computing and data science applications. Julia leverages a unified and coordinated single-language and ecosystem paradigm and has a…

The Julia programming language was designed to fill the needs of scientific computing by combining the benefits of productivity and performance languages. Julia allows users to write untyped scripts easily without needing to worry about…

Programming Languages · Computer Science 2023-10-27 Benjamin Chung

We introduce the Scheduling.jl Julia package, which is intended for collaboratively conducting scheduling research and for sharing implementations of algorithms. It provides the fundamental building blocks for implementing scheduling…

Data Structures and Algorithms · Computer Science 2020-03-12 Sascha Hunold , Bartłomiej Przybylski

We present MultiObjectiveAlgorithms.jl, an open-source Julia library for solving multi-objective optimization problems written in JuMP. MultiObjectiveAlgorithms.jl implements a number of different solution algorithms, which all rely on an…

Optimization and Control · Mathematics 2026-05-26 Oscar Dowson , Xavier Gandibleux , Gökhan Kof

Dynamic languages have become popular for scientific computing. They are generally considered highly productive, but lacking in performance. This paper presents Julia, a new dynamic language for technical computing, designed for performance…

Programming Languages · Computer Science 2012-09-25 Jeff Bezanson , Stefan Karpinski , Viral B. Shah , Alan Edelman

This year marks the consolidation of Julia (https://julialang.org/), a programming language designed for scientific computing, as the first stable version (1.0) has been released, in August 2018. Among its main features, expressiveness and…

Instrumentation and Methods for Astrophysics · Physics 2018-12-05 Maurizio Tomasi , Mosè Giordano

Sequential sampling models (SSMs) are a widely used framework describing decision-making as a stochastic, dynamic process of evidence accumulation. SSMs popularity across cognitive science has driven the development of various software…

Mathematical Software · Computer Science 2025-12-17 Kianté Fernandez , Dominique Makowski , Christopher Fisher

JuMP is an algebraic modeling language embedded in the Julia programming language. JuMP allows users to model optimization problems of a variety of kinds, including linear programming, integer programming, conic optimization, semidefinite…

Programming Languages · Computer Science 2023-03-21 Miles Lubin , Oscar Dowson , Joaquim Dias Garcia , Joey Huchette , Benoît Legat , Juan Pablo Vielma

Machine learning is driving development across many fields in science and engineering. A simple and efficient programming language could accelerate applications of machine learning in various fields. Currently, the programming languages…

Machine Learning · Computer Science 2020-05-19 Kaifeng Gao , Gang Mei , Francesco Piccialli , Salvatore Cuomo , Jingzhi Tu , Zenan Huo

We present StochasticPrograms.jl, a user-friendly and powerful open-source framework for stochastic programming written in the Julia language. The framework includes both modeling tools and structure-exploiting optimization algorithms.…

Optimization and Control · Mathematics 2022-09-07 Martin Biel , Mikael Johansson

Motivation: This paper presents libRoadRunner 2.0, an extensible, high-performance, cross-platform, open-source software library for the simulation and analysis of models expressed using Systems Biology Markup Language SBML). Results:…

Quantitative Methods · Quantitative Biology 2022-03-03 Ciaran Welsh , Jin Xu , Lucian Smith , Matthias König , Kiri Choi , Herbert M. Sauro

Julia is a mature general-purpose programming language, with a large ecosystem of libraries and more than 12000 third-party packages, which specifically targets scientific computing. As a language, Julia is as dynamic, interactive, and…

We present BSTModelKit.jl, an open-source Julia package for constructing, solving, and analyzing Biochemical Systems Theory (BST) models of biochemical networks. The package implements S-system representations, a canonical power-law…

Molecular Networks · Quantitative Biology 2026-03-20 Sandra Vadhin , Jeffrey D. Varner

Julia has been heralded as a potential successor to Python for scientific machine learning and numerical computing, boasting ergonomic and performance improvements. Since Julia's inception in 2012 and declaration of language goals in 2017,…

Machine Learning · Computer Science 2024-12-23 Edward Berman , Jacob Ginesin

Satisfiability modulo theories (SMT) is a core tool in formal verification. While the SMT-LIB specification language can be used to interact with theorem proving software, a high-level interface allows for faster and easier specifications…

Logic in Computer Science · Computer Science 2024-12-05 Emiko Soroka , Mykel J. Kochenderfer , Sanjay Lall

Advances in bioengineering and biomedicine demand a deep understanding of the dynamic behavior of biological systems, ranging from protein pathways to complex cellular processes. Biological networks like gene regulatory networks and protein…

Biomolecules · Quantitative Biology 2023-10-31 Mayalen Etcheverry , Michael Levin , Clément Moulin-Frier , Pierre-Yves Oudeyer
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