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This article introduces a highly parallel algorithm for molecular dynamics simulations with short-range forces on single node multi- and many-core systems. The algorithm is designed to achieve high parallel speedups for strongly…

Computational Physics · Physics 2013-11-20 R. Meyer

Large-scale simulations of plasmas are essential for advancing our understanding of fusion devices, space, and astrophysical systems. Particle-in-Cell (PIC) codes have demonstrated their success in simulating numerous plasma phenomena on…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-07-05 Steven W. D. Chien , Jonas Nylund , Gabriel Bengtsson , Ivy B. Peng , Artur Podobas , Stefano Markidis

The increasing availability of GPUs for scientific computing has prompted interest in accelerating quantum chemical calculations through their use. The complexity of integral kernels for high angular momentum basis functions however often…

Matrix multiplication is a fundamental kernel in large-scale artificial intelligence and scientific computing, but its performance on conventional electronic accelerators is increasingly constrained by memory bandwidth and energy…

Emerging Technologies · Computer Science 2026-04-15 Hailong Gong , Haibo Zhang , Amanda S. Barnard , Mahbub Hassan , Matt Woolley , Rajkumar Buyya

High-performance computing (HPC) is reshaping computational drug discovery by enabling large-scale, time-efficient molecular simulations. In this work, we explore HPC-driven pipelines for Alzheimer's disease drug discovery, focusing on…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-03 Paul Ruiz Alliata , Diana Rubaga , Daniel Kumlin , Alberto Puliga

Mesoscopic numerical simulations provide a unique approach for the quantification of the chemical influences on red blood cell functionalities. The transport Dissipative Particles Dynamics (tDPD) method can lead to such effective multiscale…

Computational Physics · Physics 2017-06-07 Ansel L. Blumers , Yu-Hang Tang , Zhen Li , Xuejin Li , George E. Karniadakis

Numerical studies of shock waves in large scale systems via kinetic simulations with millions of particles are too computationally demanding to be processed in serial. In this work we focus on optimizing the parallel performance of a…

Computational Physics · Physics 2015-07-10 Jim Howell , Wolfgang Bauer , Dirk Colbry , Rodney Pickett , Alec Staber , Irina Sagert , Terrance Strother

This study presents advanced neural network architectures including Convolutional Neural Networks (CNN), Recurrent Neural Networks (RNN), Long Short-Term Memory Networks (LSTMs), and Deep Belief Networks (DBNs) for enhanced ECG signal…

Hardware Architecture · Computer Science 2023-07-18 Kayode Inadagbo , Baran Arig , Nisanur Alici , Murat Isik

The structural dynamics of biological macromolecules, such as proteins, DNA/RNA, or their complexes, are strongly influenced by protonation changes of their typically many titratable groups, which explains their pH sensitivity. In turn,…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-06 Bartosz Kohnke , Eliane Briand , Carsten Kutzner , Helmut Grubmüller

The Event Horizon Telescope (EHT) has recently released high-resolution images of accretion flows onto two supermassive black holes. Our physical understanding of these images depends on accuracy and precision of numerical models of plasma…

Instrumentation and Methods for Astrophysics · Physics 2023-03-08 Monika Moscibrodzka , Aristomenis Yfantis

This article presents an optimized algorithm and implementation for calculating resolution-of-the-identity Hartree-Fock (RI-HF) energies and analytic gradients using multiple Graphics Processing Units (GPUs). The algorithm is especially…

Computational Physics · Physics 2024-07-31 Ryan Stocks , Elise Palethorpe , Giuseppe M. J. Barca

The introduction of accelerator devices such as graphics processing units (GPUs) has had profound impact on molecular dynamics simulations and has enabled order-of-magnitude performance advances using commodity hardware. To fully reap these…

Computational Physics · Physics 2020-10-28 Szilárd Páll , Artem Zhmurov , Paul Bauer , Mark Abraham , Magnus Lundborg , Alan Gray , Berk Hess , Erik Lindahl

With large-scale Integral Field Spectroscopy (IFS) surveys of thousands of galaxies currently under-way or planned, the astronomical community is in need of methods, techniques and tools that will allow the analysis of huge amounts of data.…

Instrumentation and Methods for Astrophysics · Physics 2015-12-22 Georgios Bekiaris , Karl Glazebrook , Christopher J. Fluke , Roberto Abraham

We present a GPU-accelerated cosmological simulation code, PhotoNs-GPU, based on algorithm of Particle Mesh Fast Multipole Method (PM-FMM), and focus on the GPU utilization and optimization. A proper interpolated method for truncated…

Instrumentation and Methods for Astrophysics · Physics 2021-12-28 Qiao Wang , Chen Meng

We introduce FastPM, a highly-scalable approximated particle mesh N-body solver, which implements the particle mesh (PM) scheme enforcing correct linear displacement (1LPT) evolution via modified kick and drift factors. Employing a…

Cosmology and Nongalactic Astrophysics · Physics 2017-09-14 Yu Feng , Man-Yat Chu , Uros Seljak , Patrick McDonald

Cryptographic schemes like Fully Homomorphic Encryption (FHE) and Zero-Knowledge Proofs (ZKPs), while offering powerful privacy-preserving capabilities, are often hindered by their computational complexity. Polynomial multiplication, a core…

Cryptography and Security · Computer Science 2024-10-04 Rabimba Karanjai , Sangwon Shin , and Wujie Xiong , Xinxin Fan , Lin Chen , Tianwei Zhang , Taeweon Suh , Weidong Shi , Veronika Kuchta , Francesco Sica , Lei Xu

As fusion energy devices advance, plasma simulations are crucial for reactor design. Our work extends BIT1 hybrid parallelization by integrating MPI with OpenMP and OpenACC, focusing on asynchronous multi-GPU programming. Results show…

As an important application of spatial databases in pathology imaging analysis, cross-comparing the spatial boundaries of a huge amount of segmented micro-anatomic objects demands extremely data- and compute-intensive operations, requiring…

Databases · Computer Science 2012-08-02 Kaibo Wang , Yin Huai , Rubao Lee , Fusheng Wang , Xiaodong Zhang , Joel H. Saltz

A finite-difference Micromagnetic simulation code written in MATLAB is presented with Graphics Processing Unit (GPU) acceleration. The high performance of Graphics Processing Unit (GPU) is demonstrated compared to a typical Central…

Computational Engineering, Finance, and Science · Computer Science 2015-01-30 Ru Zhu

This research delves into sophisticated neural network frameworks like Convolutional Neural Networks (CNN), Recurrent Neural Networks (RNN), Long Short-Term Memory Networks (LSTMs), and Deep Belief Networks (DBNs) for improved analysis of…

Machine Learning · Computer Science 2023-11-22 Nisanur Alici , Kayode Inadagbo , Murat Isik