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In recent years, there has been an increasing number of frameworks developed for biomedical entity and relation extraction. This research effort aims to address the accelerating growth in biomedical publications and the intricate nature of…

Computation and Language · Computer Science 2024-08-14 Minh Nguyen , Phuong Le

To extract the structured representations of open-domain events, Bayesian graphical models have made some progress. However, these approaches typically assume that all words in a document are generated from a single event. While this may be…

Computation and Language · Computer Science 2019-08-27 Rui Wang , Deyu Zhou , Yulan He

Over the recent years, the emergence of large language models (LLMs) has given rise to a proliferation of domain-specific models that are intended to reflect the particularities of linguistic context and content as a correlate of the…

Computation and Language · Computer Science 2024-02-20 Chris von Csefalvay

The increased adoption of Electronic Health Records(EHRs) has brought changes to the way the patient care is carried out. The rich heterogeneous and temporal data space stored in EHRs can be leveraged by machine learning models to capture…

Machine Learning · Computer Science 2019-04-11 Maria Bampa

Large language models (LLMs) are increasingly applied in biomedical domains, yet their reliability in drug-safety prediction remains underexplored. In this work, we investigate whether LLMs incorporate socio-demographic information into…

Computation and Language · Computer Science 2025-10-17 Siying Liu , Shisheng Zhang , Indu Bala

FDA Medical Device recalls are critical and time-sensitive events, requiring swift identification of impacted devices to inform the public of a recall event and ensure patient safety. The OpenFDA device recall dataset contains valuable…

Computation and Language · Computer Science 2024-06-11 Miriam Farrington

The surging amount of biomedical literature & digital clinical records presents a growing need for text mining techniques that can not only identify but also semantically relate entities in unstructured data. In this paper we propose a text…

Computation and Language · Computer Science 2021-12-28 Hasham Ul Haq , Veysel Kocaman , David Talby

A biomedical relation statement is commonly expressed in multiple sentences and consists of many concepts, including gene, disease, chemical, and mutation. To automatically extract information from biomedical literature, existing biomedical…

Computation and Language · Computer Science 2021-01-13 Po-Ting Lai , Zhiyong Lu

Adverse drug interactions are a critical concern in pharmacovigilance, as both clinical trials and spontaneous reporting systems often lack the breadth to detect complex drug interactions. This study introduces a computational framework for…

Applications · Statistics 2025-04-02 Jules Bangard , Einar Holsbø , Kristian Svendsen , Vittorio Perduca , Etienne Birmelé

The rapidly growth of biomedical literature creates challenges acquiring specific medical information. Current biomedical question-answering systems primarily focus on short-form answers, failing to provide comprehensive explanations…

Computation and Language · Computer Science 2026-01-05 Lovely Yeswanth Panchumarthi , Sumalatha Saleti , Sai Prasad Gudari , Atharva Negi , Praveen Raj Budime , Harsit Upadhya

Timely and accurate extraction of Adverse Drug Events (ADE) from biomedical literature is paramount for public safety, but involves slow and costly manual labor. We set out to improve drug safety monitoring (pharmacovigilance, PV) through…

Long-sequence transformers are designed to improve the representation of longer texts by language models and their performance on downstream document-level tasks. However, not much is understood about the quality of token-level predictions…

Computation and Language · Computer Science 2023-03-15 Kamil Bujel , Andrew Caines , Helen Yannakoudakis , Marek Rei

Biomedical entity linking and event extraction are two crucial tasks to support text understanding and retrieval in the biomedical domain. These two tasks intrinsically benefit each other: entity linking disambiguates the biomedical…

Computation and Language · Computer Science 2023-05-25 Xiaochu Li , Minqian Liu , Zhiyang Xu , Lifu Huang

The mining of adverse drug events (ADEs) is pivotal in pharmacovigilance, enhancing patient safety by identifying potential risks associated with medications, facilitating early detection of adverse events, and guiding regulatory…

Artificial Intelligence · Computer Science 2024-10-04 Pranab Sahoo , Ayush Kumar Singh , Sriparna Saha , Aman Chadha , Samrat Mondal

Event linking connects event mentions in text with relevant nodes in a knowledge base (KB). Prior research in event linking has mainly borrowed methods from entity linking, overlooking the distinct features of events. Compared to the…

Computation and Language · Computer Science 2024-06-07 I-Hung Hsu , Zihan Xue , Nilay Pochh , Sahil Bansal , Premkumar Natarajan , Jayanth Srinivasa , Nanyun Peng

Post--marketing pharmacovigilance is essential for identifying adverse drug reactions (ADRs) that elude detection during pre--marketing clinical trials. This study explores a novel approach that integrates an adverse event (AE) ontology…

Adverse Drug Reactions (ADRs) are a leading cause of morbidity and mortality. Existing prediction methods rely mainly on chemical similarity, machine learning on structured databases, or isolated target profiles, but often fail to integrate…

Biomolecules · Quantitative Biology 2026-03-03 David Jackson , Michael Gertz , Jürgen Hesser

We extend BeamAttack, an adversarial attack algorithm designed to evaluate the robustness of text classification systems through word-level modifications guided by beam search. Our extensions include support for word deletions and the…

Computation and Language · Computer Science 2025-07-04 Arnisa Fazla , Lucas Krauter , David Guzman Piedrahita , Andrianos Michail

With the advancements in Artificial intelligence (AI) and the accumulation of healthrelated big data, it has become increasingly feasible and commonplace to leverage machine learning technologies to analyze clinical and omics metadata to…

Genomics · Quantitative Biology 2022-04-14 Attayeb Mohsen , Lokesh P. Tripathi , Kenji Mizuguchi

In this work, we present a manually annotated corpus for Adverse Event (AE) extraction from discharge summaries of elderly patients, a population often underrepresented in clinical NLP resources. The dataset includes 14 clinically…

Computation and Language · Computer Science 2025-06-19 Imane Guellil , Salomé Andres , Atul Anand , Bruce Guthrie , Huayu Zhang , Abul Hasan , Honghan Wu , Beatrice Alex