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Cells can often choose among several stably heritable phenotypes. Examples are the expression of genes in eukaryotic cells where long chromosomal regions can adopt persistent and heritable silenced or active states, that may be associated…
Many single-cell observables are highly heterogeneous. A part of this heterogeneity stems from age-related phenomena: the fact that there is a nonuniform distribution of cells with different ages. This has led to a renewed interest in…
The evolution of antimicrobial resistance generally occurs in an environment where antimicrobial concentration is variable, which has dramatic consequences on the microorganisms' fitness landscape, and thus on the evolution of resistance.…
Many areas of agriculture rely on honey bees to provide pollination services and any decline in honey bee numbers can impact on global food security. In order to understand the dynamics of honey bee colonies we present a discrete time…
When predicting the fate and consequences of recurring deleterious mutations in self-fertilising populations most models developed make the assumption that populations have discrete non-overlapping generations. This makes them biologically…
Fixed tree topologies are widely used in phylodynamic analyses to reduce computational burden, yet the consequences of this assumption remain insufficiently understood. Here, we systematically assess the impact of various fixed-topology…
The problem of finding optimal set of users for influencing others in the social network has been widely studied. Because it is NP-hard, some heuristics were proposed to find sub-optimal solutions. Still, one of the commonly used assumption…
Crop yield is affected by various soil and environmental parameters and can vary significantly. Therefore, a crop yield estimation model which can predict pre-harvest yield is required for food security. The study is conducted on tea forms…
This paper presents an integrated modelling assessment that estimated the sensitivities of five endogenous factors in commercial rangelands, i.e. number of active farmers, profits, stocking rate, standing herbage biomass, and soil erosion,…
Building sustainable food systems that are resilient to climate change will require improved agricultural management and policy. One common practice that is well-known to benefit crop yields is crop rotation, yet there remains limited…
Previous evolutionary studies demonstrated how evaluating evolving agents in variable environmental conditions enable them to develop solutions that are robust to environmental variation. We demonstrate how the robustness of the agents can…
In this paper we study a model of age-structured ecological populations in continuous interaction with a community of harvesters. We propose an individual-based model for this feedback interactions and prove its convergence to a system of…
The magnitude and variability of Earth's biodiversity have puzzled scientists ever since paleontologic fossil databases became available. We identify and study a model of interdependent species where both endogenous and exogenous impacts…
More than 95% of the crop genetic erosion articles analyzed in [9] reported changes in diversity, with nearly 80% providing evidence of loss. The lack of diversity presents a severe risk to the security of global food systems. Without seed…
Microbial populations in the natural environment are likely to experience growth conditions very different from those of a typical laboratory xperiment. In particular, removal rates of biomass and substrate are unlikely to be balanced under…
Changing base composition during the evolution of biological sequences can mislead some of the phylogenetic inference techniques in current use. However, detecting whether such a process has occurred may be difficult, since convergent…
We present a modified water-vegetation model to investigate the mechanistic relationship between infiltration-soil moisture feedback and vegetation pattern in arid/semi-arid ecosystems. Employing Turing pattern formation theory, we drive…
Bacteria populations rely on mechanisms such as quorum sensing to coordinate complex tasks that cannot be achieved by a single bacterium. Quorum sensing is used to measure the local bacteria population density, and it controls cooperation…
Predictions from machine learning algorithms can vary across random seeds, inducing instability in downstream debiased machine learning estimators. We formalize random seed stability via a concentration condition and prove that subbagging…
We develop a model for investigating the impact of rainstorm variability on the formation of banded vegetation patterns in dryland ecosystems. Water input, during rare rainstorms, is modeled as an instantaneous kick to the soil water. The…