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We analyze an approach to managing the COVID-19 pandemic without shutting down the economy while staying within the capacity of the healthcare system. We base our analysis on a detailed heterogeneous epidemiological model, which takes into…

Populations and Evolution · Quantitative Biology 2020-05-12 David Gershon , Alexander Lipton , Hagai Levine

Epidemics of infectious diseases have accompanied humans for a long time and, depending on the scale, cause various undesirable social and economic consequences. During the ongoing COVID-19 pandemic, governments of many countries impose…

Physics and Society · Physics 2020-05-07 Andrzej Szymkowiak , Piotr Kulawik , Kishokanth Jeganathan , Paulina Guzik

During the ongoing COVID-19 pandemic, mathematical models of epidemic spreading have emerged as powerful tools to produce valuable predictions of the evolution of the pandemic, helping public health authorities decide which intervention…

Dynamical Systems · Mathematics 2021-11-18 Lorenzo Zino , Ming Cao

Epidemic spread in a population is traditionally modeled via compartmentalized models which represent the free evolution of disease in absence of any intervention policies. In addition, these models assume full observability of disease…

Populations and Evolution · Quantitative Biology 2021-06-16 Nitin Kamra , Yizhou Zhang , Sirisha Rambhatla , Chuizheng Meng , Yan Liu

We present a local spread model of disease transmission on a regular network and compare different control options ranging from treating the whole population to local control in a well-defined neighborhood of an infectious individual.…

Biological Physics · Physics 2015-05-30 Katarzyna Oles , Ewa Gudowska-Nowak , Adam Kleczkowski

When considering airborne epidemic spreading in social systems, a natural connection arises between mobility and epidemic contacts. As individuals travel, possibilities to encounter new people either at the final destination or during the…

Physics and Society · Physics 2024-05-10 Jesús A. Moreno López , Sandro Meloni , Jose J. Ramasco

While many efforts are currently devoted to vaccines development and administration, social distancing measures, including severe restrictions such as lockdowns, remain fundamental tools to contain the spread of COVID-19. A crucial point…

Systems and Control · Electrical Eng. & Systems 2021-09-03 Mauro Bisiacco , Gianluigi Pillonetto

Almost every country in the world is battling to limit the spread of COVID-19. As the world strives to get an effective medication to control the disease, appropriate intervention measures, for now, remains one of the effective methods to…

Populations and Evolution · Quantitative Biology 2022-05-13 Samuel Okyere , Joseph Ackora-Prah , Ebenezer Bonyah , Kwaku Forkuoh Darkwah

Pandemic influenza has the epidemic potential to kill millions of people. While various preventive measures exist (i.a., vaccination and school closures), deciding on strategies that lead to their most effective and efficient use remains…

Machine Learning · Computer Science 2018-06-18 Pieter Libin , Timothy Verstraeten , Diederik M. Roijers , Jelena Grujic , Kristof Theys , Philippe Lemey , Ann Nowé

In the context of the ongoing Covid-19 pandemic, several reports and studies have attempted to model and predict the spread of the disease. There is also intense debate about policies for limiting the damage, both to health and to the…

Physics and Society · Physics 2020-05-04 Harshad Khadilkar , Tanuja Ganu , Deva P Seetharam

The detection and management of diseases become quite complicated when pathogens contain asymptomatic phenotypes amongst their ranks, as evident during the recent COVID-19 pandemic. Spreading of diseases has been studied extensively under…

Physics and Society · Physics 2021-10-27 Saptarshi Sinha , Deep Nath , Soumen Roy

This study explores the application of Pontryagin's Maximum Principle to derive optimal strategies for controlling the spread of COVID-19, leveraging a novel compartmental model to capture the disease dynamics. We prioritize three key…

Despite extensive work on the interplay between traffic dynamics and epidemic spreading, the control of epidemic spreading by routing strategies has not received adequate attention. In this paper, we study the impact of efficient routing…

Physics and Society · Physics 2016-11-23 Han-Xin Yang , Zhi-Xi Wu

We devise a theoretical model for the optimal dynamical control of an infectious disease whose diffusion is described by the SVIR compartmental model. The control is realized through implementing social rules to reduce the disease's spread,…

Optimization and Control · Mathematics 2022-08-10 Alessandro Ramponi , Maria Elisabetta Tessitore

The main focus of this chapter is on public health control strategies which are currently the main way to mitigate COVID-19 pandemic. We introduce and compare compartmental models of increasing complexity for COVID-19 transmission to…

Populations and Evolution · Quantitative Biology 2020-12-14 Redouane Qesmi , Aayah Hammoumi

We study variants of the SEIR model for interpreting some qualitative features of the statistics of the Covid-19 epidemic in France. Standard SEIR models distinguish essentially two regimes: either the disease is controlled and the number…

Populations and Evolution · Quantitative Biology 2020-06-25 Jean Dolbeault , Gabriel Turinici

The death toll for Covid-19 may be reduced by dividing the population into two classes, the vulnerable and the fit, with different lockdown regimes. Instead of one reproduction number there now are four parameters. These make it possible to…

Populations and Evolution · Quantitative Biology 2020-10-05 Guus Balkema

The design of an efficient curing policy, able to stem an epidemic process at an affordable cost, has to account for the structure of the population contact network supporting the contagious process. Thus, we tackle the problem of…

Optimization and Control · Mathematics 2017-12-04 Stefania Ottaviano , Francesco De Pellegrini , Stefano Bonaccorsi , Piet Van Mieghem

The process of contagiousness spread modelling is well-known in epidemiology. However, the application of spread modelling to banking market is quite recent. In this work, we present a system of ordinary differential equations, simulating…

Optimization and Control · Mathematics 2018-02-19 Olena Kostylenko , Helena Sofia Rodrigues , Delfim F. M. Torres

Ever since the outbreak of the COVID-19 epidemic, various public health control strategies have been proposed and tested against the coronavirus SARS-CoV-2. We study three specific COVID-19 epidemic control models: the susceptible, exposed,…

Systems and Control · Electrical Eng. & Systems 2021-06-09 Zhe Xu , Bo Wu , Ufuk Topcu